Protein Alignment CG8774 and trhde.1

DIOPT Version :10

• Sequence 1: NP_650274.2
• Gene: CG8774 / 41635
• FlyBaseID: FBgn0038136
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: XP_001345457.3
• Gene: trhde.1 / 100006808
• ZFINID: ZDB-GENE-170406-2
• Length: 994
• Species: Danio rerio
• Alignment Length: 982
• Identity: 304/982 - (30%)
• Similarity: 499/982 - (50%)
• Gaps: 92/982 - (9%)

  Fly     9 QVVLSWAVVAFATATVVVAVQ---KAQLERDLRDVQDKIDVFEEWSGESRTRMKR--------ED 62
            ::||.:| ::..|..:|.|:.   ....||...:....:..    :|.|.::.|:        .|
Zfish    38 RLVLGFA-ISILTLIIVTAIAITLSVSFERCAAESSGALAA----NGSSNSKWKQSRDGNISHRD 97

  Fly    63 TTD-------YRLPTNLVPTHYELYWHPDLETGNFTGQQRISIKVVEATNQIILHSYLLDITSVY 120
            :.|       .|||..|.|.||:|.....:|..:|:|:..|..:.|.:|..|:|||..|::..|.
Zfish    98 SEDGQQPWRHLRLPATLRPRHYDLRLTVHMENFSFSGEVNIEFECVNSTKLIVLHSDRLELDKVL 162

  Fly   121 VLNREVEKFELEEERQF-------LIITLTEELAVDASITLGIIFGGQMKDKLVGLYSSTY-LNE 177
            |.:...:...:..:|:|       .:|.|..|:....:..:.|.|...::.:|:|.:.|:| ||
Zfish   163 VFSDSKKAGAMRIQRRFHYQPKQVYVIALHREMKPLRTYKINITFTAHIEHELLGFFRSSYMLN- 226

  Fly   178 AGATRTISTTKFEPTYARQAFPCFDEPAMKATFAITVVHPSGSYHAVSNM--QQTESNYLGDYTE 240
             |..|.::.|:|.||:||:||||||||..||||.:::.|.| ||.::|||  :.|.|:..|..|.
Zfish   227 -GERRFLAVTQFSPTHARKAFPCFDEPIYKATFRVSLKHES-SYQSLSNMPVEATTSDEDGWVTN 289

  Fly   241 AIFETSVSMSTYLVCIIVSDFASQSTTVKANGIGEDFSMQAYA--TSHQINKVEFALEFGQAVTE 303
            . |..:..||||.:...|.:| :....|..||:    .::.||  .:.|....::||...:.:.:
Zfish   290 H-FSRTPRMSTYYLAWAVCNF-TYKEAVADNGV----LIRLYARPDAIQSGSGDYALRITKRLLQ 348

  Fly   304 YYIQYYKVPYPLTKLDMAAIPDFASGAMEHWGLVTYRETALLYDPSYSSTANKQSIAGTLAHEIA 368
            :|..|:||.|.|.|||:.|:|.....|||:|||..:.|..:|.||..||.:.:..:...:.|||.
Zfish   349 FYQDYFKVKYSLPKLDLLAVPKHPYSAMENWGLSVFVEQKILLDPEVSSFSYQMELTVVVVHEIC 413

  Fly   369 HQWFGNLVTMKWWNDLWLNEGFARYMQYKGVNAVHPDWGMLEQ-FQIVALQPVLLYDAKLSSHPI 432
            |||||:|||..||.|:||.||||.|.:|.|.:.:.|.|.|.:| |....|..|:|.|...|||||
Zfish   414 HQWFGDLVTPVWWEDVWLKEGFAHYFEYIGADFLFPKWNMEKQRFLTDVLHEVMLLDGLASSHPI 478

  Fly   433 VQKVESPDEITAIFDTISYEKGGSVIRMLETLVGAEKFEEAVTNYLVKHQFNNTVTDDFLTEVEA 497
            .|:|....:|..:||.|:|:||.::||||..::|...|:.|:.:||:.|.:.|...||...::..
Zfish   479 SQQVFEATDIDRVFDWIAYKKGAALIRMLANVMGQTLFQRALNDYLMTHMYGNAARDDLWNKLSE 543

  Fly   498 VV----TDLDIKKLMLTWTEQMGYPVLNVSK--VADGSFKVTQQRF-------LSNPASYEEAPS 549
            .:    .|::|.::|..||.||||||:.:||  ..|.|..::|:.|       :.||..:.::
Zfish   544 AMQREGKDINITQVMDRWTLQMGYPVVTISKNDSLDNSITISQEHFVYDTDAKIQNPELFNKS-- 606

  Fly   550 DSAYGYKWSVPITWFADDGSE---NSFIY---DYDVDSVGIAVPSEVQWIKLNVNQTGYYRVNYE 608
                 ::|.:|:|....:.|.   .:.|:   ..:...||..|..  .|:..|:|||||:||||:
Zfish   607 -----FQWQIPLTLAVGNASHISTETIIWVTNKSEAHRVGHMVGE--TWLLGNINQTGYFRVNYD 664

  Fly   609 ESLWALLIQQLTTSPARFEIADRGHLLNDAFALADANQLSYKIPLDMTAYLAQERDFVPWYVASN 673
            ...|.||||||.::|....:.:|..|::|.|.||.|..|...:||.|.:||:||.:|:||:.||.
Zfish   665 LHNWKLLIQQLMSNPTIISVGNRAGLIDDVFNLARAGYLPQNVPLQMISYLSQEPEFLPWHAASR 729

  Fly   674 KLRSLHRSLMFSEGYVSYLTYARSLIAGVYEEVGWTVDADN-------HLKNRLRVSILTAACAL 731
            .|..|.:.|..:..:..:..|....:...|.::||...:.:       :....|:..::..||:.
Zfish   730 ALYQLDKLLDRTLDHSLFSDYVLRQVEPKYHKLGWPATSPDGSFMHSAYQTEELQREVIMLACSF 794

  Fly   732 GVPDCLQQASERFSTFLENPTTRPSPDLREIVYYYGMQQSTSQSSWDQLFQLFVAETDASEKLKL 796
            |...|.:||....|.::.:...|..|::|:|||..|: ....:..|:.::..|.:.|..|||..|
Zfish   795 GNKHCHRQAVSLISDWISSNKNRIPPNVRDIVYCTGV-SLMDEDVWEFIWMKFHSSTAVSEKKVL 858

  Fly   797 MYGLSGVRNSQYLFDFLAQASSDESIVRSQDYFTCVQYIAANPVGEPVVWEFYREQWPQLTTRFG 861
            :..|: ..::.:|.:.|...|....:|..||....:.::|.||:|..:.|.::||:|..|.:|:|
Zfish   859 LEALT-CSDNIFLLNRLLNLSLTSDLVPDQDVIDVIIHVARNPLGRHLAWRYFREKWDILNSRYG 922

  Fly   862 ----LNNRNFGRLIAQITANFASSVKLEEVQHFFSKYPESGAGANSRLEAVETIKYNIEWLSRNE 922
                :|:    :||:.:|....:..:|.|::.|.  ....|..|.:...|||.::.|::|....:
Zfish   923 EALFMNS----KLISGVTEFLNTEAELNELKEFI--LTSGGESAPAFARAVEIVQANVKWHILFQ 981

  Fly   923 ADITDWL 929
            .....||
Zfish   982 EQFYQWL 988

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8774	NP_650274.2	M1_APN-Q_like	75..513	CDD:341064	161/454 (35%)
		ERAP1_C	592..912	CDD:463368	98/330 (30%)
trhde.1	XP_001345457.3	M1_APN-Q_like	118..563	CDD:341064	161/453 (36%)
		ERAP1_C	648..975	CDD:463368	99/334 (30%)