Protein Alignment CG8773 and LAP2

DIOPT Version :10

• Sequence 1: NP_650273.2
• Gene: CG8773 / 41634
• FlyBaseID: FBgn0038135
• Length: 994
• Species: Drosophila melanogaster
• Sequence 2: NP_014353.1
• Gene: LAP2 / 855682
• SGDID: S000004990
• Length: 671
• Species: Saccharomyces cerevisiae
• Alignment Length: 719
• Identity: 174/719 - (24%)
• Similarity: 266/719 - (36%)
• Gaps: 206/719 - (28%)

  Fly   116 PEKIDYRLPGTLKPTHYDLYLFPNIETGEFSGQETITITVEEATDQIVLHS-LNLNISSVSIMNT 179
            |..|:.|.|.  :...||              |.|::    ...|..|||: |||::|......:
Yeast    42 PLSIEQRRPS--RSPEYD--------------QSTLS----NYKDFAVLHTDLNLSVSFEKSAIS 86

  Fly   180 GSDT----------------------LEILETTVDAVR-EFLIFQLNEPLTKGRTVR-------- 213
            ||.|                      |::.|..:|..: :|.|.|..|||.....:.
Yeast    87 GSVTFQLKKLHEGKNKSDELHLDTSYLDVQEVHIDGSKADFQIEQRKEPLGSRLVINNASCNDNF 151

  Fly   214 -LHIGFEGSMANKIVGLYSSSYVKEDETR--KWIATSKFEPTYARQAFPCFDEPALKAEFTITLV 275
             |:|.|.  ..:|...|   .::...:|:  |....|:.|..:||..|||||.|::|:.||.::.
Yeast   152 TLNIQFR--TTDKCTAL---QWLNSKQTKGGKPYVFSQLEAIHARSLFPCFDTPSVKSTFTASIE 211

  Fly   276 HPSGEDYHALSNMNV-DSSVSQGAFQEVTFAKSVPMSTYLACFIVSDFAYKQVSIDTKGIGETFS 339
            .|...   ..|.:.: |:|.....::   |.:.||:..||......|       :.:..||.  .
Yeast   212 SPLPV---VFSGIRIEDTSKDTNIYR---FEQKVPIPAYLIGIASGD-------LSSAPIGP--R 261

  Fly   340 MSVYATPEQL---------DKVDLAVTIGKGVIEYYIDYFQIAYPLPKLDMAAIPDFVSGAMEHW 395
            .:||..|.:|         |......|..|.:.||....:.|        :..:..:..|.||..
Yeast   262 STVYTEPFRLKDCQWEFENDVEKFIQTAEKIIFEYEWGTYDI--------LVNVDSYPYGGMESP 318

  Fly   396 GLVTYRETSLLYDEATSSATNKQRIASVIAHEFAHMWFGNLVTMNWWNDLWLNEGFASFVEYLGV 460
            .:.....|.:.:|.:.         ..|||||.||.|.|||||...||..|||||:..::|...:
Yeast   319 NMTFATPTLIAHDRSN---------IDVIAHELAHSWSGNLVTNCSWNHFWLNEGWTVYLERRII 374

  Fly   461 DAVYPE----------W--------KMRDQFTVSTLHSVLTLDGTLGSHPIIQTVENPDQITEIF 507
            .|::.|          |        .|:|....|||...|. |.|           :||   :.|
Yeast   375 GAIHGEPTRHFSALIGWSDLQNSIDSMKDPERFSTLVQNLN-DNT-----------DPD---DAF 424

  Fly   508 DTITYSKGSSLVRMLEDFL-GETTFRQAVTNYLNEYKYSTAETGNFFTEIDKLELGYNVTEIML- 570
            .|:.|.||.:|:..||..| |:..|...:.:|..::...:.:|..|   :|.|...|...:.:|
Yeast   425 STVPYEKGFNLLFHLETILGGKAEFDPFIRHYFKKFAKKSLDTFQF---LDTLYEFYPEKKEILD 486

  Fly   571 -----TWTVQMGLPVVT--IEKVSDTEYKLTQK-----RFLSNPNDYDADHEPSEFNYRWSIPIT 623
                 ||..:.|:|...  |..::|..|:|..|     :.|....|:     .||||   :|.|.
Yeast   487 SVDWETWLYKPGMPPRPHFITALADNVYQLADKWVEMAQHLKTTEDF-----RSEFN---AIDIK 543

  Fly   624 YFTSSDSV--VQRLWFYHDQSEITVTVPAAVEWIKF-------------------NADQV-GYYR 666
            .|.|:..|  ::.|    .|:..:...|...:|.||                   ||:.| ..::
Yeast   544 DFNSNQLVLFLETL----TQNGHSNKKPKDFDWAKFPVASRALLDIYQDNIVKSQNAEVVFKMFK 604

  Fly   667 VNYDTDL---WNDLADQLVVQPSAFGSVDRAHLLNDAFALADST--QLPYATAFELTRYLDKETD 726
            ......|   :..|||.|       |:|.|...:...:.|.:|.  :|..||       .||..|
Yeast   605 FQIFAKLQEEYKHLADWL-------GTVGRMKFVRPGYRLLNSVDRRLALAT-------FDKFKD 655

  Fly   727 -YVP 729
             |.|
Yeast   656 TYHP 659

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8773	NP_650273.2	KLF9_13_N-like	<17..118	CDD:425361	1/1 (100%)
		M1_APN-Q_like	130..573	CDD:341064	124/512 (24%)
		ERAP1_C	654..973	CDD:463368	24/102 (24%)
LAP2	NP_014353.1	leuko_A4_hydro	57..669	CDD:274120	169/702 (24%)