DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8773 and AT1G63770

DIOPT Version :9

Sequence 1:	NP_650273.2	Gene:	CG8773 / 41634	FlyBaseID:	FBgn0038135	Length:	994	Species:	Drosophila melanogaster
Sequence 2:	NP_001117543.4	Gene:	AT1G63770 / 842681	AraportID:	AT1G63770	Length:	987	Species:	Arabidopsis thaliana

Alignment Length:	1032	Identity:	204/1032 - (19%)
Similarity:	350/1032 - (33%)	Gaps:	324/1032 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    98 TVTPGSTASTSEPGTTASPEKIDYRLPGTLKPTHYDLYLFPNIETGEFSGQETITIT-------- 154
            :|...|....:|.....:|::|  .|....||.:|    |..::.....|:|...::
plant    78 SVATESVPDKAEDSKMDAPKEI--FLKNYTKPDYY----FETVDLSFSLGEEKTIVSSKIKVSPR 136

  Fly   155 VEEATDQIVLHSLNLNISSVSI----MNTGSDTLEILETTVDAV--REFLIFQLNEPLTKGRTVR 213
            |:.::..:||...:|.:.||.:    :..|...|:....|:.::  .|..:.:::..:...:...
plant   137 VKGSSAALVLDGHDLKLLSVKVEGKLLKEGDYQLDSRHLTLPSLPAEESFVLEIDTEIYPHKNTS 201

  Fly   214 LHIGFEGSMANKIVGLYSSS--YVKEDETRKWIATSKFEPTYARQAFPCFDEPALKAEFTITL-- 274
            |.            |||.||  :..:.|...:...:.::           |.|.:.|::|..:
plant   202 LE------------GLYKSSGNFCTQCEAEGFRKITFYQ-----------DRPDIMAKYTCRVEG 243

  Fly   275 ---VHPSGEDYHALSNMNVDSSVSQG--------AFQEVTFAKSVPMSTYLACFIVSDFAYKQVS 328
               ::|.     .|||.|:   :|||        |..|..|.|        .|::.:..|.:.||
plant   244 DKTLYPV-----LLSNGNL---ISQGDIEGGRHYALWEDPFKK--------PCYLFALVAGQLVS 292

  Fly   329 ID---TKGIGETFSMSVYATPEQLDKVDLAVTIGKGVIEYYIDYFQIAYPLPKLDMAAIPDFVSG 390
            .|   |...|...|:.::...|.|.|...|:...|..:::..|.|.:.|.|...::.|:|||..|
plant   293 RDDTFTTRSGRQVSLKIWTPAEDLPKTAHAMYSLKAAMKWDEDVFGLEYDLDLFNIVAVPDFNMG 357

  Fly   391 AMEHWGLVTYRETSLLYDEATSSATNKQRIASVIAHEFAHMWFGNLVTMNWWNDLWLNEGFASFV 455
            |||:..|..:....:|....|::..:...|..||.||:.|.|.||.||...|..|.|.||...|
plant   358 AMENKSLNIFNSKLVLASPETATDADYAAILGVIGHEYFHNWTGNRVTCRDWFQLSLKEGLTVF- 421

  Fly   456 EYLGVDAVYPEWKMRDQ--------FTVSTLHSVLTL-------DGTLGSHPIIQTVENPDQITE 505
                          |||        .||..:..|..|       |....:||:     .|....:
plant   422 --------------RDQEFSSDMGSRTVKRIADVSKLRIYQFPQDAGPMAHPV-----RPHSYIK 467

  Fly   506 I--FDTIT-YSK------------GSSLVRMLEDFLGETTFRQAVTNYLNEYKYSTAETGNFFTE 555
            :  |.|:| |.|            |:.:|||.:..||...||:.:..|...:........:||..
plant   468 MDNFYTVTVYEKVWLFTNSVLLYAGAEVVRMYKTLLGTQGFRKGIDLYFERHDEQAVTCEDFFAA 532

  Fly   556 IDKLELGYNVTEI--MLTWTVQMGLPVVTIEKVSDTEYKLTQKRFLSN--PNDYDADHEPSEFNY 616
            :...    |..:.  .|.|..|.|.|||.:....:.:.:....:|...  |.......||:
plant   533 MRDA----NNADFANFLQWYSQAGTPVVKVVSSYNADARTFSLKFSQEIPPTPGQPTKEPT---- 589

  Fly   617 RWSIPIT--YFTSSDSVVQRLWFYHDQSEITVTVPAAVEWIKFNADQVGYYRVNYDTDLWNDLAD 679
              .||:.  ...||...:.....:||.:..|::..:.:..:....::.          :::|:.:
plant   590 --FIPVVVGLLDSSGKDITLSSVHHDGTVQTISGSSTILRVTKKEEEF----------VFSDIPE 642

  Fly   680 QLVVQPSAFGSVD-----RAHLLND--AFALADSTQLPYATAFELTRYLDKETDYVPWSVAASRL 737
            :.|  ||.|....     ...|.||  .|.||..:.       |..|          |.  |.::
plant   643 RPV--PSLFRGFSAPVRVETDLSNDDLFFLLAHDSD-------EFNR----------WE--AGQV 686

  Fly   738 TSLKRTLYYTSTYAKYKKYATALIEPIYT-ALTWTVGEDHLDNRLRVTALSAACSLGLESCLTEA 801
            .:.|..|...|.:.:.|..|   :.|.:. .|...:.:..||......|::          |...
plant   687 LARKLMLNLVSDFQQNKPLA---LNPKFVQGLGSVLSDSSLDKEFIAKAIT----------LPGE 738

  Fly   802 GEQFNAWLAKPEDRPKADVRETVYYYGIQSVGSQEDWDAVWEL--FVNESDASE----------- 853
            ||                         |..:.:..|.|||..:  ||.:..|||
plant   739 GE-------------------------IMDMMAVADPDAVHAVRKFVRKQLASELKEELLKIVEN 778

  Fly   854 -------------------KSKLMYGLSAIQIPWILQRYIDLAWNEEYVRGQ--DYFTCLTYISA 897
                               |:..:..|::::.|    .|::||.||..:...  |.|..|..:|.
plant   779 NRSTEAYVFDHSNMARRALKNTALAYLASLEDP----AYMELALNEYKMATNLTDQFAALAALSQ 839

  Fly   898 NP--VGESLVWDYVR-------------------------ENWQRLVD----------------- 918
            ||  ..:.::.|:..                         ||.::|:|
plant   840 NPGKTRDDILADFYNKWQDDYLVVNKWFLLQSTSDIPGNVENVKKLLDHPAFDLRNPNKVYSLIG 904

  Fly   919 -----------RFGLNERYLGNLI-------PSITAR----FSTQTKLEEMEQFFAK 953
                       :.|...::||:::       |.:.:|    ||...:.:|..|..||
plant   905 GFCGSPVNFHAKDGSGYKFLGDIVVQLDKLNPQVASRMVSAFSRWKRYDETRQGLAK 961

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8773	NP_650273.2	Peptidase_M1	122..515	CDD:279741	101/454 (22%)
		M1_APN_2	130..579	CDD:189008	114/512 (22%)
		ERAP1_C	655..969	CDD:288671	68/407 (17%)
AT1G63770	NP_001117543.4	pepN	92..987	CDD:237585	201/1018 (20%)
AT1G63770	NP_001117543.4	M1_APN_1	103..985	CDD:189007	198/1005 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0308
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D110058at2759
OrthoFinder	1	1.000	-	-		FOG0000044
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X67
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.820