Protein Alignment CG8773 and npepps

DIOPT Version :10

• Sequence 1: NP_650273.2
• Gene: CG8773 / 41634
• FlyBaseID: FBgn0038135
• Length: 994
• Species: Drosophila melanogaster
• Sequence 2: NP_001072690.1
• Gene: npepps / 780147
• XenbaseID: XB-GENE-1008338
• Length: 875
• Species: Xenopus tropicalis
• Alignment Length: 893
• Identity: 287/893 - (32%)
• Similarity: 460/893 - (51%)
• Gaps: 61/893 - (6%)

  Fly   122 RLPGTLKPTHYDLYLFPNIETGEFSGQETITITVEEATDQIVLHSLNLNISSVSIMNTGSDTLEI 186
            |||..::|.:|.|.|.|::....|.|:...|:.|:.||:|||::..:::|.:.|....|.:.:..
 Frog     9 RLPTDVRPVNYGLCLKPDLIDFTFEGKLEATVEVQNATNQIVMNCADIDIITASYAPEGDEEIHA 73

  Fly   187 LETTVDAVREFLIFQLNEPLTKGRTVRLHIGFEGSMANKIVGLYSSSYVKEDETRKWIATSKFEP 251
            .........|.:.......|.||..: |.|.|.|.:.:|:.|.|.|.|.......::.|.::||.
 Frog    74 TGFNYQNEDEKVTLSFPSTLQKGAGM-LKIDFVGELNDKMKGFYRSKYATATGEVRYAAVTQFEA 137

  Fly   252 TYARQAFPCFDEPALKAEFTITLVHPSGEDYHALSNMNV--------DSSVSQGAFQEVTFAKSV 308
            |.||:||||:||||:||.|.:.|:.|  :|..||||||:        |.::     .||.||::.
 Frog   138 TDARRAFPCWDEPAIKATFDVILIVP--KDRVALSNMNLIDRKPYPDDENL-----VEVKFARTP 195

  Fly   309 PMSTYLACFIVSDFAYKQVSIDTKGIGETFSMSVYATPEQLDKVDLAVTIGKGVIEYYIDYFQIA 373
            .|||||..|:|.::.:    ::|:. .:...:.||....:.::...|:.:....:.:|.|||.:.
 Frog   196 IMSTYLVAFVVGEYDF----VETRS-SDGVLVRVYTPVGKAEQGKFALEVAAKTLPFYKDYFNVP 255

  Fly   374 YPLPKLDMAAIPDFVSGAMEHWGLVTYRETSLLYDEATSSATNKQRIASVIAHEFAHMWFGNLVT 438
            |||||:|:.||.||.:||||:|||||||||:||.|...|.::::|.:|.|:.||.||.|||||||
 Frog   256 YPLPKIDLIAIADFAAGAMENWGLVTYRETALLIDPKNSCSSSRQWVALVVGHELAHQWFGNLVT 320

  Fly   439 MNWWNDLWLNEGFASFVEYLGVDAVYPEWKMRDQFTVSTLHSVLTLDGTLGSHPIIQTVENPDQI 503
            |.||..|||||||||::|||.||..:||:.:..||..:.......||....||||..:|.:|.::
 Frog   321 MEWWTHLWLNEGFASWIEYLCVDHCFPEYDIWTQFVSADYTRAQELDALENSHPIEVSVGHPSEV 385

  Fly   504 TEIFDTITYSKGSSLVRMLEDFLGETTFRQAVTNYLNEYKYSTAETGNFFTEIDKLELGYNVTEI 568
            .||||.|:||||:|::|||.|::|:..||:.:..||.:::...|.|.:.:..:::.. |..:..:
 Frog   386 DEIFDAISYSKGASVIRMLHDYIGDEDFRKGMNQYLTKFQEKNAATEDLWESLEQAS-GKPIAAV 449

  Fly   569 MLTWTVQMGLPVVTIE---KVSDTEYKLTQKRFLSN--PNDYDADHEPSEFNYRWSIPITYFTSS 628
            |.|||.|||.|::.:|   |......||:||:|.::  ||        |:.:|:|.:||:..||.
 Frog   450 MNTWTKQMGFPLICVESEQKEDSVVLKLSQKKFCASGAPN--------SDDSYQWMVPISICTSE 506

  Fly   629 DSVVQRLWFYHDQSEITVTVPAAV--EWIKFNADQVGYYRVNYDTDLWNDLAD---QLVVQPSAF 688
            ......:....|:.|:||.:....  :|:|.|...||:||..|.|.:...|..   .|.:||
 Frog   507 SPASATVKILMDKPEMTVVLEGVKPHQWVKLNPGTVGFYRTQYSTTMLESLLPGIRDLSLQP--- 568

  Fly   689 GSVDRAHLLNDAFALADSTQLPYATAFELTRYLDKETDYVPWSVAASRLTSLKRTLYYTSTYAKY 753
              |||..|.||.|:||.:..:..|...::......|.:|..||..:..|..|...|.:|..:.:.
 Frog   569 --VDRLGLQNDLFSLARAGMINTAEVLKVMEAFVNEPNYTVWSDLSCNLGILSTLLSHTDFHEEI 631

  Fly   754 KKYATALIEPIYTALTW--TVGEDHLDNRLRVTALSAACSLGLESCLTEAGEQFNAWLAKPEDRP 816
            :.:...:..||...|.|  ..||.|||..||...|......|.:..|.||..:|...:   :.|.
 Frog   632 QCFVRDVFSPIGQRLGWDPKPGEGHLDALLRGLVLGKLGKAGHQPTLEEARRRFKEHV---DGRN 693

  Fly   817 --KADVRETVYYYGIQSVGSQEDWDAVWELFVNESDASEKSKLMYGLSAIQIPWILQRYIDLAWN 879
              .||:|..||...::. |.....:.:.:|........||:::...|.||....::::.:..:.:
 Frog   694 VLSADLRSPVYVTVLKH-GDNSTLETMMKLHKQADMQEEKNRIERVLGAIAEQDLIKKVLSFSLS 757

  Fly   880 EEYVRGQDYFTCLTYIS-ANPVGESLVWDYVRENWQRLVDRF--GLNERYLGNLIPSITARFSTQ 941
            |: ||.||....:..:: .:.:|....|::|::||:.|.:|:  |.   .:..||......|::.
 Frog   758 ED-VRPQDTVCVIGGVAGGSKLGRKCAWNFVKDNWEELYNRYQGGF---LISRLIKLSLDGFASD 818

  Fly   942 TKLEEMEQFFAKYPEAGAGTAARVRALETVKNNIVWLAENLEGVDAWL 989
            ....|::.||..:|...|....: :..|.:..|..||..:.|.:..:|
 Frog   819 KMAAEIKAFFDAHPAPSAERTVQ-QCCENILLNAGWLKRDAEAIHHYL 865

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8773	NP_650273.2	KLF9_13_N-like	<17..118	CDD:425361
		M1_APN-Q_like	130..573	CDD:341064	169/450 (38%)
		ERAP1_C	654..973	CDD:463368	83/328 (25%)
npepps	NP_001072690.1	M1_APN-Q_like	17..455	CDD:341064	170/451 (38%)
		ERAP1_C	534..847	CDD:463368	83/326 (25%)