Protein Alignment CG8773 and Rnpepl1

DIOPT Version :10

• Sequence 1: NP_650273.2
• Gene: CG8773 / 41634
• FlyBaseID: FBgn0038135
• Length: 994
• Species: Drosophila melanogaster
• Sequence 2: NP_001258106.1
• Gene: Rnpepl1 / 684035
• RGDID: 1595210
• Length: 724
• Species: Rattus norvegicus
• Alignment Length: 775
• Identity: 159/775 - (20%)
• Similarity: 259/775 - (33%)
• Gaps: 204/775 - (26%)

  Fly    77 PGSTAEPGSTAEPGSTASPGSTVTPGSTASTSEPGTTASPEKIDYRLPGTLKPTHYDLYLFPNIE 141
            ||:.|.|   |.|.....|...|...|:|..             :||      .|..|.|....|
  Rat    11 PGAEAAP---ARPPPEPPPALEVASASSAQL-------------FRL------RHLQLGLELRPE 53

  Fly   142 TGEFSGQETITI---------TVEEATDQIVLHSLNLNISSVSIMN--------TGSDTLEILET 189
            ..|.:|...:.:         .|.:|...:.|||::...:|.:..:        .||.  ..|..
  Rat    54 ARELAGCLVLELCALRPAPRALVLDAHPALRLHSVSFRRASATSESPCTFAFPAPGSG--PPLPA 116

  Fly   190 TVDAVREF-----LIFQLNEPLT---KGRTVRLHIGFEGSMANKIVGLYSSSYVKEDETRKWIAT 246
            ..||....     |.|:| :|.|   ...|:.|....:.....:::..|:|:    |....|...
  Rat   117 FADAPGAESAGCPLAFRL-DPFTDYGSSLTITLPPEVQAHQPFQVIVRYTST----DAPAIWWLD 176

  Fly   247 SKFEPTYA---------------RQAFPCFDEPALKAEFTITLVHPSGEDYHALSNMNVDSSVSQ 296
            .  |.||.               |..|||||.||:|..::..:..|||        :.|..|.:|
  Rat   177 P--ELTYGNAKPFVFTQGHSVCNRSFFPCFDTPAVKCTYSAVVKAPSG--------VQVLMSATQ 231

  Fly   297 GAFQE----VTFAKSVPMSTYLACFIVSDFAYKQVSIDTKGIGETFSMSVYATPEQLDKVDLAVT 357
            .|:.|    ..|....|:..||...:..|.  |...|..:.       .|:|.|..|   ..|.:
  Rat   232 SAYVEEEGLYHFHMEHPVPAYLVALVAGDL--KPADIGPRS-------RVWAEPCLL---PTATS 284

  Fly   358 IGKGVIEYYIDYFQIAY-PL--PKLDMAAI-PDFVSGAMEHWGLVTYRETSLLYDEATSSATNKQ 418
            ...|.:|.::...:..| |.  .:.|:..: |.|...|||: ..:|:..:|:|..:        :
  Rat   285 KLSGAVEQWLSAAERLYGPYMWGRYDIVFLPPSFPIVAMEN-PCLTFIISSILESD--------E 340

  Fly   419 RIASVIAHEFAHMWFGNLVTMNWWNDLWLNEGFASFVEYLGVDAVYPE--WKMRDQFTVSTLHSV 481
            .:...:.||.||.||||.||...|.::||:||.|::.:.......|..  ..:...|.:..||..
  Rat   341 FLVIDVIHEVAHSWFGNAVTNATWEEMWLSEGLATYAQRRITTETYGAAFTCLETAFRLDALHRQ 405

  Fly   482 LTLDGTLGSHPIIQTVE-------NPDQITEIFDTITYSKGSSLVRMLEDFLGE-TTFRQAVTNY 538
            :.|   ||....:..::       ||..:..:|   ||.||...|..|....|: ..|...:..|
  Rat   406 MRL---LGEDSPVSKLQVKLEPGVNPSHLMNLF---TYEKGYCFVYYLSQLCGDPQRFDDFLRAY 464

  Fly   539 LNEYKYSTAETG-------NFFTEIDKLELGYNVTEIMLTWTVQMGLPVVTIEKVSDTEYKLTQK 596
            :.:||:::....       :||.|:.:..:..........|....|.|:        .|..|:|.
  Rat   465 VEKYKFTSVVAQDLLDSFLSFFPELKEQSVDCRAGLEFERWLNATGPPL--------AEPDLSQG 521

  Fly   597 RFLSNPNDYDADHEPSEFNYRWSIPITYFTSSDSVVQRLWFYHDQSEITVTVPAAVEWIKFNADQ 661
            ..|:.|.:                          .:.:||......:...:..|
  Rat   522 SSLTRPVE--------------------------ALFQLWTAEPLEQAAASASA----------- 549

  Fly   662 VGYYRVNYDTDLWNDLADQLVVQPSAFGSVDRAHLLNDAFALADSTQLPYATAFELTRYLDKETD 726
                   .|...|.      ..|.:.|  :||         |.|.:.||......|::......|
  Rat   550 -------IDISKWR------TFQTALF--LDR---------LLDGSPLPQEVVMSLSKCYSSLLD 590

  Fly   727 YVPWSVAASRLTSLKRTLYYTSTYAKYKKYATALIEPIYTALTWTVGEDHLDNRLRVTAL 786
            .:...:....|..:.|..||...: :.:::....:..:||...:   ||.....|:..||
  Rat   591 SMNTEIRIRWLQIVVRNDYYPDLH-RVRRFLENQMSRMYTIPLY---EDLCTGALKSFAL 646

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8773	NP_650273.2	KLF9_13_N-like	<17..118	CDD:425361	10/40 (25%)
		M1_APN-Q_like	130..573	CDD:341064	113/507 (22%)
		ERAP1_C	654..973	CDD:463368	23/133 (17%)
Rnpepl1	NP_001258106.1	M1_LTA4H	30..507	CDD:341062	119/539 (22%)
		Leuk-A4-hydro_C	555..668	CDD:462686	22/113 (19%)