Protein Alignment CG8773 and Enpep

DIOPT Version :10

• Sequence 1: NP_650273.2
• Gene: CG8773 / 41634
• FlyBaseID: FBgn0038135
• Length: 994
• Species: Drosophila melanogaster
• Sequence 2: NP_071587.2
• Gene: Enpep / 64017
• RGDID: 621228
• Length: 945
• Species: Rattus norvegicus
• Alignment Length: 932
• Identity: 366/932 - (39%)
• Similarity: 540/932 - (57%)
• Gaps: 46/932 - (4%)

  Fly    80 TAEPGSTAEPGSTASPGSTVTPGSTASTSEPGTTASPEKIDYRLPGTLKPTHYDLYLFPNIETGE 144
            :.|||:|..|.:.....||..|....:........|.|..::|||..::|.||||.:...:|...
  Rat    42 SCEPGTTPAPSNPPPHTSTALPPQDQNVCPDSDDESGEWKNFRLPDFIQPVHYDLEVKVLMEEDR 106

  Fly   145 FSGQETITITVEEATDQIVLHSLNLNISSV-SIMNTGSDTLEILETTVDAVREFLIFQLNEPL-- 206
            ::|..:|::.:.:.|..:.||.....|:.: .:.....:.:.|........:|:::.|..|.|
  Rat   107 YTGIVSISVNLSKDTRDLWLHIRETRITKLPELRRPSGEQVPIRRCFEYKKQEYVVIQAEEDLAA 171

  Fly   207 TKGRTV-RLHIGFEGSMANKIVGLYSSSYVKEDETRKWIATSKFEPTYARQAFPCFDEPALKAEF 270
            |.|.:| ||.|.|||.:...:||.|.::|.::.:| |.||.:..|||.||::|||||||..||.:
  Rat   172 TSGDSVYRLTIEFEGWLNGSLVGFYRTTYTEDGQT-KSIAATDHEPTDARKSFPCFDEPNKKATY 235

  Fly   271 TITLVHPSGEDYHALSNMNVDSSVS-QGAFQEVTFAKSVPMSTYLACFIVSDFAYKQVSIDTKGI 334
            .|:|:||  ::|.|||||.|:...: ...:::.||.|||||||||.||.|..|...|   .|...
  Rat   236 NISLIHP--KEYSALSNMPVEKEETLDNDWKKTTFMKSVPMSTYLVCFAVHQFTSIQ---RTSRS 295

  Fly   335 GETFSMSVYATPEQLDKVDLAVTIGKGVIEYYIDYFQIAYPLPKLDMAAIPDFVSGAMEHWGLVT 399
            |:  .::||..|.|....:.|..|.|.|.:::.|||.:.|.|||||..|||||.:||||:|||||
  Rat   296 GK--PLTVYVQPNQKQTAEYAANITKAVFDFFEDYFAMEYSLPKLDKIAIPDFGTGAMENWGLVT 358

  Fly   400 YRETSLLYDEATSSATNKQRIASVIAHEFAHMWFGNLVTMNWWNDLWLNEGFASFVEYLGVDAVY 464
            ||||:||||...|:::|:||:|||:|||..|.||||:|||:||:|||||||||||.|:|||:...
  Rat   359 YRETNLLYDPLLSASSNQQRVASVVAHELVHQWFGNIVTMDWWDDLWLNEGFASFFEFLGVNHAE 423

  Fly   465 PEWKMRDQFTVSTLHSVLTLDGTLGSHPIIQTVENPDQITEIFDTITYSKGSSLVRMLEDFLGET 529
            .:|:|..|..:..:..|...|..:.|||::.||..|.:||.:||.|:||||:|::|||:|::...
  Rat   424 ADWQMLSQVLLEDVLPVQEDDSLMSSHPVVVTVSTPAEITSVFDGISYSKGASILRMLQDWITPE 488

  Fly   530 TFRQAVTNYLNEYKYSTAETGNFFTEIDKLELGYN--VTEIMLTWTVQMGLPVVTIEKVSDTEYK 592
            .|::....||..:|:..|:|.:|:   |.||...|  |.|:|.|||.|||.||||:    ..:..
  Rat   489 KFQKGCQIYLENFKFKNAKTSDFW---DSLEKASNQPVKEVMDTWTSQMGYPVVTV----SGKQN 546

  Fly   593 LTQKRFLSNPNDYDAD--HEPSEFNYRWSIPITYFTSSDSVVQRLWFYHDQSEITVTVPAAVE-- 653
            :||||||.   ||.||  ..||...|.|:|||.:..:.:|   .:..|:..:...:|:.|.:.
  Rat   547 VTQKRFLL---DYKADPSQPPSALGYTWNIPIKWTENGNS---NITVYYRSNREGITLNANLSGD 605

  Fly   654 -WIKFNADQVGYYRVNYDTDLWNDLADQLVVQPSAFGSVDRAHLLNDAFALADSTQLPYATAFEL 717
             ::|.|.|.:|:|||||:.:.|:.:|:.|......|.|.||:..::||||||.:..|.|..|..|
  Rat   606 GFLKINPDHIGFYRVNYEAETWDWIAETLSSNHMNFSSADRSSFIDDAFALARAQLLDYEKALNL 670

  Fly   718 TRYLDKETDYVPWS---VAASRLTSL---KRTLYYTSTYAKYKKYATALIEPIYTALTWTVGEDH 776
            ||||..|.|::||.   .|.|.:.|:   .|.|     |...:.|..:.::||..:|.|.....|
  Rat   671 TRYLTSEKDFLPWERVISAVSYIISMFEDDREL-----YPLIETYFRSQVKPIADSLGWQDTGSH 730

  Fly   777 LDNRLRVTALSAACSLGLESCLTEAGEQFNAWLAKPEDRPKADVRETVYYYGIQSVGSQEDWDAV 841
            :...||.:.|..||.:|....|..|.:.|.|||...|..| .::|..||.||:|:.|::..|:..
  Rat   731 ITKLLRASVLGFACKMGAGEALGNASQLFEAWLKGNESIP-VNLRLLVYRYGMQNSGNEAAWNYT 794

  Fly   842 WELFVNESDASEKSKLMYGLSAIQIPWILQRYIDLAWNEEYVRGQDYFTCLTYISANPVGESLVW 906
            .|.:...|.|.||.||:|||::::...:|.||:::..:...::.||.||.:.|||.|..|:|:.|
  Rat   795 LEQYQKTSLAQEKEKLLYGLASVKDVTLLARYLEMLKDPNIIKTQDVFTVIRYISYNSYGKSMAW 859

  Fly   907 DYVRENWQRLVDRFGLNERYLGNLIPSITARFSTQTKLEEMEQFFAKYPEAGAGTAARVRALETV 971
            ::::.||..||:||.:|:||||.:: :|...|:|:.:|.:|:.||||||.||||...|.:.||||
  Rat   860 NWIQLNWDYLVNRFTINDRYLGRIV-TIAEPFNTELQLWQMQSFFAKYPNAGAGAKPREQVLETV 923

  Fly   972 KNNIVWLAENLEGVDAWLDKQP 993
            ||||.||..|.:.:..|....|
  Rat   924 KNNIEWLKLNRKSISEWFTSMP 945

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8773	NP_650273.2	KLF9_13_N-like	<17..118	CDD:425361	9/37 (24%)
		M1_APN-Q_like	130..573	CDD:341064	190/449 (42%)
		ERAP1_C	654..973	CDD:463368	123/324 (38%)
Enpep	NP_071587.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	45..77		7/31 (23%)
		M1_APN-Q_like	92..531	CDD:341064	190/449 (42%)
		ERAP1_C	607..925	CDD:463368	123/324 (38%)