Protein Alignment CG8773 and SP1029

DIOPT Version :9

• Sequence 1: NP_650273.2
• Gene: CG8773 / 41634
• FlyBaseID: FBgn0038135
• Length: 994
• Species: Drosophila melanogaster
• Sequence 2: NP_001263065.1
• Gene: SP1029 / 53473
• FlyBaseID: FBgn0263236
• Length: 932
• Species: Drosophila melanogaster
• Alignment Length: 924
• Identity: 302/924 - (32%)
• Similarity: 470/924 - (50%)
• Gaps: 98/924 - (10%)

  Fly   121 YRLPGTLKPTHYDLYLFPNIETGE---FSGQETITITVEEATDQIVLHSLNLNI--SSVSIMNTG 180
            ||||.:|:|..|.|.:...:|..|   |||...|.|...|.|..:.|||.||.|  |.:::...|
  Fly    32 YRLPTSLRPQKYHLRILTLLENPEDLRFSGSVKILIEALENTKNVTLHSKNLTIDESQITLRQIG 96

  Fly   181 SDTLE---ILETTVDAVREFLIFQLNEPLTKGRTVRLHIGFEGSMANKIVGLYSSSYVKED--ET 240
            .:..:   :..|.|:...:|.|....:.|..|.|..|::.|...:..::.|.|.||| |:.  ..
  Fly    97 GEGKKENCVSSTAVNPSHDFYILNTCQELLAGNTYELYMPFAADLNRQLEGYYRSSY-KDPVANL 160

  Fly   241 RKWIATSKFEPTYARQAFPCFDEPALKAEFTITLVHPSGEDYHALSNMNVDSSVSQGAFQE---V 302
            .|||:.::|||..||.||||||||..||.|.:||.:  .:.|.|:|||....:.......:   .
  Fly   161 TKWISVTQFEPASARLAFPCFDEPDFKAPFVVTLGY--HKKYTAISNMPEKETKPHETLADYIWC 223

  Fly   303 TFAKSVPMSTYLACFIVSDFAYKQVSIDTKGIGETFSMSVYATPEQLDKVDLAVTIGKGVIEYYI 367
            .|.:||||||||..:.|:||::|..::....:..|     :|.|..:|:.|.|...|..|::||.
  Fly   224 EFQESVPMSTYLVAYSVNDFSHKPSTLPNSALFRT-----WARPNAIDQCDYAAQFGPKVLQYYE 283

  Fly   368 DYFQIAYPLPKLDMAAIPDFVSGAMEHWGLVTYRETSLLYDEATSSATNKQRIASVIAHEFAHMW 432
            .:|.|.:||||:|..|:|||.:||||:||||||||.:|||..|.||..:|||:|||:|||.||.|
  Fly   284 QFFGIKFPLPKIDQIAVPDFSAGAMENWGLVTYREIALLYSAAHSSLADKQRVASVVAHELAHQW 348

  Fly   433 FGNLVTMNWWNDLWLNEGFASFVEYLGVDAVYPEWKMRDQFTVSTLHSVLTLDGTLGSHPIIQTV 497
            |||||||.||.|||||||||::|..|||:.:.|||:..:|.::|.|.::...|....||||.:.:
  Fly   349 FGNLVTMKWWTDLWLNEGFATYVASLGVENINPEWRSMEQESLSNLLTIFRRDALESSHPISRPI 413

  Fly   498 ENPDQITEIFDTITYSKGSSLVRMLEDFLGETTFRQAVTNYLNEYKYSTAETGNFFTEIDK---- 558
            :...:|:|.||.|:|.|||:::||:..||||.:||..:..||.::.|..||..|.:..:.:
  Fly   414 QMVSEISESFDQISYQKGSTVLRMMHLFLGEESFRSGLQAYLQKFSYKNAEQDNLWESLTQAAHK 478

  Fly   559 ---LELGYNVTEIMLTWTVQMGLPVVTIEKVSDTEY-----KLTQKRFLSNPNDYDADHEPSEFN 615
               |...|::..||.:||:|.|.||:.:.:    :|     ||.|:|:|.|.....|
  Fly   479 YRSLPKSYDIKSIMDSWTLQTGYPVINVTR----DYAARTAKLNQERYLLNTQVARA-------- 531

  Fly   616 YR---WSIPITYFTSS----DSVVQRLWFY--HDQSEITVTV---PAAVEWIKFNADQVGYYRVN 668
            ||   |.:|::|.|.:    ::...:.|..  .:...:..|:   |...:|:.||......|:||
  Fly   532 YRGGCWWVPLSYTTQAVQDFNNTAPKAWMECGKNGESLPKTIQDLPGPDQWVIFNTQLSTLYKVN 596

  Fly   669 YDTDLWNDLADQLVVQPSAFGSVDRAHLLN------DAFALADSTQLPYATAFELTRYLDKETDY 727
            ||...|     :|:::....|..:|.|::|      ||..||.:.:..|..|..|..||.:|.:|
  Fly   597 YDAQNW-----KLLIETLTNGDFERIHVINRAQLIDDALYLAWTGEQDYEIAMRLIEYLQREREY 656

  Fly   728 VPWSVAASRLTSLKRTLYYTSTYAKYKKYATALIEPIYTALTWTVGEDHLDN------------- 779
            :||..|...|..:.|.:..|..:..:|:|...||.|||         :||:.
  Fly   657 LPWKSAFENLKRVGRIVRQTPDFEFFKRYMKKLILPIY---------EHLNGINDTFSAIPQQDQ 712

  Fly   780 -RLRVTALSAACSLGLESCLTEAGEQFNAWLAK--PEDRPKA--DVRETVYYYGIQSVGSQEDWD 839
             .|:...::.||...:..|:.:|...:..|.|:  |:::...  :||.|||...|:. ||..||:
  Fly   713 VLLKTMVVNWACQYQVGDCVPQALAYYRNWRAEANPDEKNPVPINVRSTVYCTSIKH-GSDSDWE 776

  Fly   840 AVWELFVNESDASEKSKLMYGLSAIQIPWILQRYIDLAWN-EEYVRGQDYFTCLTYISANPVGES 903
            .:|..:...:.|:||..::..|...:..|:||||::|.:: :|.:|.||.......::.|.||..
  Fly   777 FLWTRYKKSNVAAEKRTILTALGCSREVWLLQRYLELTFDPKEAIRKQDSMWAFQAVAFNEVGFL 841

  Fly   904 LVWDYVRENWQRLVDRFGLNERYLGNLIPSITARFSTQTKLEEMEQFFAKYPEAGAGTAARV-RA 967
            |...|..:|...:...:....:.:..|:..::.:..|.:...|.:.|.....::..|....: :.
  Fly   842 LAKKYFMDNVDFIYKFYHPLTKDMSRLLSPLSEQVITLSDFNEFKDFVNNSRQSLKGLEQAIQQT 906

  Fly   968 LETVKNNIVWLAEN 981
            ||.:..|:.|...|
  Fly   907 LEIMLTNVQWKERN 920

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8773	NP_650273.2	Peptidase_M1	122..515	CDD:279741	168/405 (41%)
		M1_APN_2	130..579	CDD:189008	188/468 (40%)
		ERAP1_C	655..969	CDD:288671	83/339 (24%)
SP1029	NP_001263065.1	Peptidase_M1	33..431	CDD:279741	168/405 (41%)
		M1_APN_2	43..502	CDD:189008	188/466 (40%)
		ERAP1_C	583..908	CDD:288671	83/339 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462025
Domainoid	1	1.000	98	1.000	Domainoid score	I364
eggNOG	1	0.900	-	-		E1_COG0308
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D110058at2759
OrthoFinder	1	1.000	-	-		FOG0000044
OrthoInspector	1	1.000	-	-		otm14800
orthoMCL	1	0.900	-	-		OOG6_100307
Panther	1	1.100	-	-	P	PTHR11533
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X67
	10	9.750