Protein Alignment CG8773 and rnpep

DIOPT Version :9

• Sequence 1: NP_650273.2
• Gene: CG8773 / 41634
• FlyBaseID: FBgn0038135
• Length: 994
• Species: Drosophila melanogaster
• Sequence 2: NP_001002741.1
• Gene: rnpep / 437014
• ZFINID: ZDB-GENE-040718-241
• Length: 626
• Species: Danio rerio
• Alignment Length: 546
• Identity: 126/546 - (23%)
• Similarity: 220/546 - (40%)
• Gaps: 136/546 - (24%)

  Fly   149 ETITITVEEATD----------QIVLHSLNLNISSVSIMNTGSDTLEI-------LETTVD---- 192
            :|:|:..::|.|          :|....|:|.:..:....:|::|:|:       .|..:|
Zfish     5 KTLTLYSDKAEDVATSSSFRQFKIEHFHLDLKVDFLQKSISGTETIELQCIQDSQSELQLDIHPS 69

  Fly   193 -AVREFLIFQLNEPLTKGRTVRLHIGFEGSMANKIVGLYSSSYVKEDETR---KWIAT------- 246
             :|.|..:.|.....|  ||..|...|. |....::..:.:::..:|:.:   ::.||
Zfish    70 LSVHEITLSQNARDWT--RTEFLTQDFT-SYGTTLLVKFPTAFSSDDKLQLAIRYTATDGPGVCW 131

  Fly   247 -------SKFEP--------TYARQAFPCFDEPALKAEFTITLVHPSGEDYHALSNMNV-DSSVS 295
                   .|.:|        ...|..|||||.||:|:.::..:..|.|  :.|:.:.|. :...:
Zfish   132 LEPEQTAGKLKPYVFTQGQAVLNRSCFPCFDTPAVKSTYSAAVQVPDG--FTAVMSANKWEQRKA 194

  Fly   296 QGAFQEVTFAKSVPMSTYLACFIVSDFAYKQVSIDTKGIGETFSMSVYATPEQLDKV-DLAVTIG 359
            .|||   .|....|:..||....|.|....:|...|:...|...:.  |..::.|.| :..:::|
Zfish   195 DGAF---LFTMEHPIPAYLVALAVGDLQSAEVGPRTRVWTEPCLLQ--AAKQEYDNVIEDFLSVG 254

  Fly   360 KGVIEYYI--DYFQIAYPLPKLDMAAIPDFVSGAMEHWGLVTYRETSLLYDEATSSATNKQRIAS 422
            :.:...|:  .|..:..|         |.|..|.||: ..:|:....||        ...:.:|.
Zfish   255 EKLFGPYVWGRYDVLFMP---------PSFPFGGMEN-PCLTFVTPCLL--------AGDRSLAD 301

  Fly   423 VIAHEFAHMWFGNLVTMNWWNDLWLNEGFASFVEYLGVDAVYPEWKMRDQFT---VSTLHSVLT- 483
            ||.||..|.|||||||...|.|.||||||..:.:......:|.|     .:|   .:|..::|.
Zfish   302 VIVHEICHSWFGNLVTNATWGDFWLNEGFTMYAQRRVCRELYGE-----AYTCLEAATGKALLRQ 361

  Fly   484 -LDGTLGSHPI------IQTVENPDQITEIFDTITYSKGSSLVRMLEDFLGE----TTFRQAVTN 537
             :|.|...||:      |:...:||   :.::...|.||...|..|....|:    .||.:|
Zfish   362 HMDNTGEDHPLNKLRVKIEPGVDPD---DTYNETPYEKGFCFVSYLAHLTGDQSRFDTFLKA--- 420

  Fly   538 YLNEYKYST--AETG-----NFFTE-----IDKLE-LGYNVTEIMLTWTVQMGLPVV-------- 581
            |:.::|:.:  ||..     .:|.|     :.|:| |.::      :|....|.|..
Zfish   421 YVEKFKFRSVLAEDALEFYLEYFPELKERNVHKIEGLDFD------SWLNVPGWPPYVPDLSAGQ 479

  Fly   582 TIEKVSDTEYKLTQKRFLSNPNDYDA 607
            |:.|.::    |..:::||:..|.::
Zfish   480 TLMKPAE----LLAEKWLSHNLDLES 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8773	NP_650273.2	Peptidase_M1	122..515	CDD:279741	100/427 (23%)
		M1_APN_2	130..579	CDD:189008	119/508 (23%)
		ERAP1_C	655..969	CDD:288671
rnpep	NP_001002741.1	leuko_A4_hydro	16..623	CDD:274120	123/535 (23%)
		M1_LTA4H	16..464	CDD:189006	115/492 (23%)
		Leuk-A4-hydro_C	484..624	CDD:286244	4/22 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0308
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810