Protein Alignment CG8773 and CG4467

DIOPT Version :9

• Sequence 1: NP_650273.2
• Gene: CG8773 / 41634
• FlyBaseID: FBgn0038135
• Length: 994
• Species: Drosophila melanogaster
• Sequence 2: NP_001036747.1
• Gene: CG4467 / 42747
• FlyBaseID: FBgn0039064
• Length: 1125
• Species: Drosophila melanogaster
• Alignment Length: 1091
• Identity: 270/1091 - (24%)
• Similarity: 452/1091 - (41%)
• Gaps: 192/1091 - (17%)

  Fly    46 LLEAGYTSTAAPTTA---STANPGSTASPGSTAEPGSTAEPGSTAEPGSTASPGSTVTPGSTAST 107
            ||.||....:...||   :.|.|.:..|.||....|...:..:..:|.:           ..|:.
  Fly    74 LLVAGIVLGSLLLTAIIIAYAGPQNDCSCGSKTVSGYETDEENNTQPFN-----------PIATN 127

  Fly   108 SEPGTTASPEKIDYRLPGTLKPTHYDLYLFPNIETGEFSGQETITITVEEATDQIVLHSLNLNIS 172
            .||...     ::..||.:::|..|.:.:.||:.|.:..||.||.:.||:.|:.||||..:||::
  Fly   128 GEPFPW-----LEKMLPTSVRPLRYMVTIHPNLTTLDVKGQVTIDLHVEKETNFIVLHIQDLNVT 187

  Fly   173 SVSIMNTGSD--TLEILETTVDAVREFLIFQLNEPLTKGRTVRLHIGFEGSMANKIVGLYSSSYV 235
            ..:|:..|..  .|:|::......|:.|..::.|.|.|.....|::.:...:..:..|.|...|.
  Fly   188 EKAIVTPGPKGYALKIVKVLEFPPRQQLYIEVKERLKKKSNYTLNLRWYSKLNPEPEGFYVDQYE 252

  Fly   236 KEDETRKWIATSKFEPTYARQAFPCFDEPALKAEFTITLVHPSGEDYH-ALSNMNVDSSVSQGAF 299
            ..:...:.:|.:.|.|..||:||||||||.::|.|.|::..   :.:| .|||..|.::...|.:
  Fly   253 SSNGVERLLAATVFRPNGARRAFPCFDEPHVRAPFRISVFR---DRFHIGLSNSIVHTTEDVGFY 314

  Fly   300 QEV-----TFAKSVPMSTYLACFIVSDFAYKQVS-----IDT------KGIGE------------ 336
            ...     .|.::.|:......::||||..:.:.     |.|      .|:|.
  Fly   315 MGTGLLRDDFIETPPLPADAVAWVVSDFQRESLQPSAAYIPTTPAPPGSGVGGKKSAQLNNYTQL 379

  Fly   337 -------------TFSMSVYATPEQ---------------------------------------- 348
                         |.|::|..||.|
  Fly   380 KGKNPPVRNITALTHSLNVNLTPRQNLTVVQPTTTTAWPVNLNGNGKPSNLTSLSQSTGSSIKRA 444

  Fly   349 -----------LDKVDLAVTIGKGVIEYYIDYFQIAYPLPKLDMAAIPDFVSGAMEHWGLVTYRE 402
                       |.:....:...:.|:||...:..|:|||.|:|..|:|......:...||||.:
  Fly   445 PSYTFYAPRDLLIRSSFILHTSRDVLEYLQTWLDISYPLTKVDFVALPSLDRNMISSLGLVTLK- 508

  Fly   403 TSLLYDEATSSATNKQ------RIASVIAHEFAHMWFGNLVTMNWWNDLWLNEGFASFVEYLGVD 461
            ||.|.|  .||.|::|      |||..:..:|    ||.:.:.....|:||.||   .::|||:.
  Fly   509 TSFLTD--PSSITSEQYQFSALRIAEAMVRQF----FGGITSRKVLKDVWLWEG---LIQYLGIH 564

  Fly   462 AVYP---EWKMRDQFTVSTLHSVLTLDGTLGSHPIIQTVENPDQITEIFDTITYSKGSSLVRMLE 523
            |:.|   .|.:|:.:.:....:.|.:|...|...|:....:.....|.|    ..|.:::..||.
  Fly   565 ALAPLQETWPLREMYLLKMATAALDIDAIQGWDSIMNGTSHDGNNEEFF----VQKTAAIFSMLH 625

  Fly   524 DFLGETTFRQAVTNYLNEYKYSTAETGNFFTEIDKLELG-YNVTEIMLTWTVQMGLPVVTIEKVS 587
            ..:||..||..:.::|...::.|||..:.:|...|...| .|:.::|..||.|.|.|::|:.|:.
  Fly   626 TAIGEDRFRGCLGSFLKVNRFRTAEPTDLWTICTKKANGSKNIKDMMTLWTHQPGFPLLTVTKMG 690

  Fly   588 DTEYKLTQKRFLSNPNDYDADHEPS----EFN---------------------------YRWSIP 621
            :: ..::|:.|  .|.::.|.|:.|    .:|                           .:|..|
  Fly   691 NS-ISISQRPF--RPAEFLAIHDDSYDGNNYNKTTLNATDMPSTVATTTQGSKHKVAPHMKWIFP 752

  Fly   622 ITYFTSSDSVVQRLWFYHDQSEITVTVPAAVEWIKFNADQVGYYRVNYDTDLWNDLADQLVVQPS 686
            :||.|..::|.:.||.  ...::|..||..|:|||.||.|.|||||.|:.|.|..|.::|...|:
  Fly   753 VTYVTDINNVSETLWM--QNVDVTFNVPENVKWIKVNAIQNGYYRVVYNDDNWASLIEELAANPN 815

  Fly   687 AFGSVDRAHLLNDAFALADSTQLPYATAFELTRYLDKETDYVPWSVAASRLTSLKRTLYYTSTYA 751
            .|.|.||..:|:|||.|..:..||......:.:||..||.|.|.::|...|...:|.|.|:..:.
  Fly   816 RFTSEDRLGMLSDAFTLCHANLLPCEITMNMIQYLPSETHYGPMALALRHLEKWRRILKYSECFL 880

  Fly   752 KYKKYATALIEPIYTALTWTVGEDHLDNRLRVTALSAACSLGLESCLTEAGEQFNAWLAKPEDRP 816
            ...::....|..:...:.|:...|.....||...|.|:........:|:|....|.:|.......
  Fly   881 MLSEFIKMKISTVMEKVGWSDDGDVATRLLRPEVLLASVLWEDIDSITKAKNMLNQYLYYNGTAI 945

  Fly   817 KADVRETVYYYGIQSVGSQEDWDAVWELFVNESDAS----EKSKLMYGLSAIQIPWILQR---YI 874
            ..::||.||...|.| |....|...||.|||....|    |:.:|:..|...:..|:..|   ::
  Fly   946 PPNLREVVYTGSILS-GEYIYWQHCWERFVNLQRTSETFVERMQLLRALGRTKDAWLQNRLLSHV 1009

  Fly   875 DLAWNEEYVRGQDYFTCLTYISANPVGESLVWDYVRENWQRLVDRFGLNERYLGNLIPSITARFS 939
            .:...||.|:      .|..|:..|.|.::...:::..|..|..|.|........:|.:||...:
  Fly  1010 TMLPTEEVVQ------VLKAIAGTPTGGAMACRFLQAKWFELEKRLGPGTISFAKVISAITQYGA 1068

  Fly   940 TQTKLEEMEQFFAKYPEAGAGTAARVRALETVKNNIVWLAENLEGVDAWLD 990
            |:...:|::....::.. |.|.:.....|.:|.:|:.|:|.:...:..|::
  Fly  1069 TKFDYDELKSLVHRFGR-GHGMSVLNMTLSSVASNVEWVARSQTSLYKWVE 1118

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8773	NP_650273.2	Peptidase_M1	122..515	CDD:279741	119/496 (24%)
		M1_APN_2	130..579	CDD:189008	136/553 (25%)
		ERAP1_C	655..969	CDD:288671	86/320 (27%)
CG4467	NP_001036747.1	Peptidase_M1	138..593	CDD:279741	115/467 (25%)
		GluZincin	145..682	CDD:301352	136/553 (25%)
		ERAP1_C	784..1078	CDD:288671	84/300 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0308
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D110058at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11533
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.920