Protein Alignment CG8773 and npepps

DIOPT Version :10

• Sequence 1: NP_650273.2
• Gene: CG8773 / 41634
• FlyBaseID: FBgn0038135
• Length: 994
• Species: Drosophila melanogaster
• Sequence 2: NP_001157499.1
• Gene: npepps / 407726
• ZFINID: ZDB-GENE-060524-3
• Length: 872
• Species: Danio rerio
• Alignment Length: 901
• Identity: 300/901 - (33%)
• Similarity: 463/901 - (51%)
• Gaps: 65/901 - (7%)

  Fly   116 PEKIDY-RLPGTLKPTHYDLYLFPNIETGEFSGQETITITVEEATDQIVLHSLNLNISSVSIMNT 179
            ||:..: |||..:.|.:|.|.|.|::....|.|:....:.|.:.|:|||::..:::|.:.|.:..
Zfish     2 PERRPFVRLPTDVYPVNYGLRLKPDLVDFTFEGKLEAAVEVTQGTNQIVMNCADIDIITASFVPD 66

  Fly   180 GSDTLEILETTVDAVREFLIFQLNEPLTKGRTVRLHIGFEGSMANKIVGLYSSSYVKEDETRKWI 244
            |.:.:...........|.:.......|.|| :..|.|.|.|.:.:|:.|.|.|.|....|.| :.
Zfish    67 GGEEINATGFNYQNEDEKVTLCFPSTLQKG-SGSLKIDFVGELNDKMKGFYRSKYSSSGEVR-YA 129

  Fly   245 ATSKFEPTYARQAFPCFDEPALKAEFTITLVHPSGEDYHALSNMNV--------DSSVSQGAFQE 301
            |.::||.|.||:||||:||||:||.|.|||:.|  :|..|||||||        |.|:     .|
Zfish   130 AVTQFEATDARRAFPCWDEPAIKATFDITLIVP--KDRVALSNMNVVDRKPYAEDQSL-----VE 187

  Fly   302 VTFAKSVPMSTYLACFIVSDFAYKQVSIDTKGIGETFSMSVYATPEQLDKVDLAVTIGKGVIEYY 366
            |.||.:..|||||..|::.::.:.: |..:.|:    ::.||....:.::...|:.:....:.:|
Zfish   188 VKFATTPIMSTYLVAFVIGEYDFVE-SQSSDGV----TVRVYTPVGKAEQGKFALEVATKTLPFY 247

  Fly   367 IDYFQIAYPLPKLDMAAIPDFVSGAMEHWGLVTYRETSLLYDEATSSATNKQRIASVIAHEFAHM 431
            .|||.:.|||||:|:.||.||.:||||:|||||||||:||.|...|.|:::|.:|.|:.||.||.
Zfish   248 KDYFSVPYPLPKIDLIAIADFAAGAMENWGLVTYRETALLIDPKNSCASSRQWVALVVGHELAHQ 312

  Fly   432 WFGNLVTMNWWNDLWLNEGFASFVEYLGVDAVYPEWKMRDQFTVSTLHSVLTLDGTLGSHPIIQT 496
            ||||||||.||..|||||||||::|||.||..:||:.:..||..:.....|.||....||||...
Zfish   313 WFGNLVTMEWWTHLWLNEGFASWIEYLCVDHCFPEYDIWTQFVSADYTRALDLDALDNSHPIEVD 377

  Fly   497 VENPDQITEIFDTITYSKGSSLVRMLEDFLGETTFRQAVTNYLNEYKYSTAETGNFFTEIDKLEL 561
            |.:|.::.||||.|:||||:|::|||.:::|:..||:.:..||.::::..|.|.:.:..:::..
Zfish   378 VGHPSEVDEIFDAISYSKGASVIRMLHNYIGDEDFRKGMNAYLLKFQHKNASTEDLWECLEQAS- 441

  Fly   562 GYNVTEIMLTWTVQMGLPVVTIEKV---SDTEYKLTQKRF-LSNP-NDYDADHEPSEFNYRWSIP 621
            |..:..:|.:||.|||.|::.:::.   ||...|::||:| .|.| ||.|..:        |.:|
Zfish   442 GKPIAAVMNSWTKQMGFPIIVVDQEQHGSDRVLKISQKKFCASGPRNDEDCPN--------WMVP 498

  Fly   622 ITYFTSSDSVVQRLWFYHDQSEITVTVP--AAVEWIKFNADQVGYYRVNYDTDLWNDLAD---QL 681
            |:..||.|....:.....||.|.||.:.  |...|||.|...||:||:.|.:.:...|..   .|
Zfish   499 ISICTSEDPSCTKTKILLDQPETTVNITNVAPDHWIKINPGTVGFYRIQYSSAMLESLLPGIRDL 563

  Fly   682 VVQPSAFGSVDRAHLLNDAFALADSTQLPYATAFELTRYLDKETDYVPWSVAASRLTSLKRTLYY 746
            .:.|     |||..|.||.|:||.:..:......::......|.:|..||..:..|..|...|.:
Zfish   564 TLLP-----VDRLGLQNDLFSLARAGMISTVEVLKVMEAFVNEPNYTVWSDLSCNLGVLSSLLSH 623

  Fly   747 TSTYAKYKKYATALIEPIYTALTW--TVGEDHLDNRLRVTALSAACSLGLESCLTEAGEQFNAWL 809
            |..:...:::...|..||...|.|  ..||.|||..||...|......|.::.|.||..:|...:
Zfish   624 TDFHEDIQEFIRDLFTPIGMKLGWDSRTGEGHLDALLRGLVLGKLGKAGHKATLEEARRRFREHV 688

  Fly   810 AKPEDRPKADVRETVYYYGIQSVGSQEDWDAVWELFVNESDASEKSKLMYGLSAIQIPWILQRYI 874
             :.:....||:|..||...::. |.....|.:.:|........||:::...|.||..|.::||.:
Zfish   689 -EGKQILSADLRSPVYLTVLKH-GDSTTLDTMLKLHKQADMQEEKNRIERVLGAIPAPDLIQRVL 751

  Fly   875 DLAWNEEYVRGQDYFTCLTYIS-ANPVGESLVWDYVRENWQRLVDRFGLNERYLG-----NLIPS 933
            :.|.:|| ||.||..:.:..:: ::..|....|.:|::||:.      |:.||.|     .||..
Zfish   752 NFALSEE-VRPQDTVSVIGGVAGSSKQGRKAAWKFVKDNWEE------LHNRYQGGFLISRLIKL 809

  Fly   934 ITARFSTQTKLEEMEQFFAKYPEAGAGTAARVRALETVKNNIVWLAENLEGVDAWL 989
            ....|:......|::.||..: .|.|......:..|.:..|..||..:.:.:..:|
Zfish   810 TVDGFAIDKMAAEVKSFFESH-HAPAAERTVQQCCENILLNAAWLKRDADDIHQYL 864

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8773	NP_650273.2	KLF9_13_N-like	<17..118	CDD:425361	1/1 (100%)
		M1_APN-Q_like	130..573	CDD:341064	173/450 (38%)
		ERAP1_C	654..973	CDD:463368	88/329 (27%)
npepps	NP_001157499.1	M1_APN-Q_like	17..454	CDD:341064	174/451 (39%)
		ERAP1_C	533..846	CDD:463368	88/327 (27%)