Protein Alignment CG8773 and Trhde

DIOPT Version :10

• Sequence 1: NP_650273.2
• Gene: CG8773 / 41634
• FlyBaseID: FBgn0038135
• Length: 994
• Species: Drosophila melanogaster
• Sequence 2: NP_001102461.1
• Gene: Trhde / 366894
• RGDID: 728895
• Length: 1066
• Species: Rattus norvegicus
• Alignment Length: 1048
• Identity: 339/1048 - (32%)
• Similarity: 516/1048 - (49%)
• Gaps: 116/1048 - (11%)

  Fly     4 TAKLVAIGLGLALTAFTVSTI-VLAVQKANLKSDLRDAQEKLDLLEAGYTSTAAPTTASTANPGS 67
            |.:.:|:...|.| ||.||.: :|||....:...||     .|  |.|         ||.|.||:
  Rat    71 TERHIAVHKRLVL-AFAVSIVALLAVTMLAVLLSLR-----FD--ECG---------ASAAMPGT 118

  Fly    68 TASPGSTAEPGSTAEPGSTAEPGSTASPGSTVTPGSTASTSEPGTTASPEK-------------- 118
            ....|...|.|     |:::.|||...........|.....|.||..:|..
  Rat   119 DGGLGGFPERG-----GNSSYPGSARRNHHAGEESSQREIGEVGTAGTPSAHPPSEEEQEQWQPW 178

  Fly   119 IDYRLPGTLKPTHYDLYLFPNIETGEFSGQETITITVEEATDQIVLHSLNLNISSVSIMNTGSDT 183
            ...||.|.|||.||:|.|...:|...|||:..:.|..:.||..:|||:..:.:..|.:..
  Rat   179 TQLRLSGHLKPLHYNLMLTAFMENFTFSGEVNVEIACQNATRYVVLHASRVAVEKVQVAE----- 238

  Fly   184 LEILETTVDAV----------REFLIFQLNEPLTKGRTVRLHIGFEGSMANKIVGLYSSSYVKED 238
                :....||          .:.|:..||..|...|...|.|.:...:.|:::|.:.||||...
  Rat   239 ----DRAFGAVPVAGFFLYPQTQVLVVVLNRTLDAQRHYNLKIIYNALIENELLGFFRSSYVIHG 299

  Fly   239 ETRKWIATSKFEPTYARQAFPCFDEPALKAEFTITLVHPSGEDYHALSNMNVDSSVSQGAFQE-- 301
            | |:::..::|.||:||:||||||||..||.|.|::.|.:  .|.:||||.|::||    |:|
  Rat   300 E-RRFLGVTQFSPTHARKAFPCFDEPIYKATFKISIKHQA--TYLSLSNMPVETSV----FEEDG 357

  Fly   302 -VT--FAKSVPMSTYLACFIVSDFAYKQVSIDTK-GIGETFSMSVYATPEQLDK--VDLAVTIGK 360
             ||  |:::..||||...:.:.:|.|::.:  || |:    .:.:||.|:.:.:  .|.|:.|.|
  Rat   358 WVTDHFSQTPLMSTYYLAWAICNFTYRETT--TKSGV----VVRLYARPDAIRRGSGDYALHITK 416

  Fly   361 GVIEYYIDYFQIAYPLPKLDMAAIPDFVSGAMEHWGLVTYRETSLLYDEATSSATNKQRIASVIA 425
            .:||:|.|||::.|.|||||:.|:|.....|||:|||..:.|..:|.|.:.||.:....:..||.
  Rat   417 RLIEFYEDYFKVPYSLPKLDLLAVPKHPYAAMENWGLSIFVEQRILLDPSVSSISYLLDVTMVIV 481

  Fly   426 HEFAHMWFGNLVTMNWWNDLWLNEGFASFVEYLGVDAVYPEWKMRDQ-FTVSTLHSVLTLDGTLG 489
            ||..|.|||:|||..||.|:||.||||.:.|::|.|.:||.|.|..| |....||.|:.|||...
  Rat   482 HEICHQWFGDLVTPVWWEDVWLKEGFAHYFEFVGTDYLYPSWNMEKQRFLTDVLHEVMLLDGLAS 546

  Fly   490 SHPIIQTVENPDQITEIFDTITYSKGSSLVRMLEDFLGETTFRQAVTNYLNEYKYSTA---ETGN 551
            |||:.|.|.....|.::||.|.|.||::|:|||.:|:|.:.|::.:.:||..:||..|   :..|
  Rat   547 SHPVSQEVLRATDIDKVFDWIAYKKGAALIRMLANFMGHSVFQRGLQDYLTIHKYGNAARNDLWN 611

  Fly   552 FFTEIDKLELGY-NVTEIMLTWTVQMGLPVVTI--EKVSDTEYKLTQKRFLSNPNDYDADHEPSE 613
            ..:|..|....| |:.|:|..||:|||.||:||  ...::....:||:.|:     ||...:...
  Rat   612 TLSEALKRNGKYVNIQEVMDQWTLQMGYPVITILGNMTAENRILITQQHFI-----YDIGAKTKA 671

  Fly   614 F-----NYRWSIPITYFTSSDSVVQR---LWFYHDQSEITVTVPAAVEWIKFNADQVGYYRVNYD 670
            .     :|.|.||:|....:.|.|..   :|..:......:|......||..|.:|.||:|||||
  Rat   672 LQLQNSSYLWQIPLTIVVGNRSHVSSEAIIWVSNKSEHHRITYLDKGSWILGNINQTGYFRVNYD 736

  Fly   671 TDLWNDLADQLVVQPSAFGSVDRAHLLNDAFALADSTQLPYATAFELTRYLDKETDYVPWSVAAS 735
            ...|..|.|||:.........:||.|::|||:||.:..||.....|:.|||.:|.|::||..|:.
  Rat   737 LRNWRLLIDQLIRNHEVLSVSNRAGLIDDAFSLARAGYLPQNIPLEIIRYLSEEKDFLPWHAASR 801

  Fly   736 RLTSLKRTLYYTSTYAKYKKYATALIEPIYTALTW--------TVGEDHLDNRLRVTALSAACSL 792
            .|..|.:.|.....|..:.:|....:...|:.|.|        .|...:....||...:..|||.
  Rat   802 ALYPLDKLLDRMENYNIFNEYILKQVATTYSKLGWPKNNFNGSVVQASYQHEELRREVIMLACSF 866

  Fly   793 GLESCLTEAGEQFNAWLAKPEDRPKADVRETVYYYGIQSVGSQEDWDAVWELFVNESDASEKSKL 857
            |.:.|..:|....:.|::...:|...:||:.||..|: |:..::.|:.:|..|.:.:..|||..|
  Rat   867 GNKHCHQQASTLISDWISSNRNRIPLNVRDIVYCTGV-SLLDEDVWEFIWMKFHSTTAVSEKKIL 930

  Fly   858 MYGLSAIQIPWILQRYIDLAWNEEYVRGQDYFTCLTYISANPVGESLVWDYVRENWQRLVDRFG- 921
            :..|:......:|.|.::|:.|.|.|..||....:.:::.||.|..|.|.:.|:.|:.|..|:|
  Rat   931 LEALTCSDDRNLLSRLLNLSLNSEVVLDQDAIDVIIHVARNPHGRDLAWKFFRDKWKILNTRYGE 995

  Fly   922 ---LNERYLGNLIPSITARFSTQTKLEEMEQFFAKYPEAGAGTAARVRALETVKNNIVWLAENLE 983
               :|.:    ||..:|...:|:.:|:|::.|...|.  |..:|:..||:|||:.|:.|.....:
  Rat   996 ALFMNSK----LISGVTEFLNTEGELKELKNFMKSYD--GVASASFSRAVETVEANVRWKRLYQD 1054

  Fly   984 GVDAWLDK 991
            .:..||.|
  Rat  1055 ELFQWLGK 1062

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8773	NP_650273.2	KLF9_13_N-like	<17..118	CDD:425361	29/101 (29%)
		M1_APN-Q_like	130..573	CDD:341064	170/465 (37%)
		ERAP1_C	654..973	CDD:463368	102/330 (31%)
Trhde	NP_001102461.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..43
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	117..177		13/64 (20%)
		M1_APN-Q_like	190..635	CDD:341064	171/466 (37%)
		ERAP1_C	720..1044	CDD:463368	102/330 (31%)