Protein Alignment CG8773 and anpepb

DIOPT Version :9

• Sequence 1: NP_650273.2
• Gene: CG8773 / 41634
• FlyBaseID: FBgn0038135
• Length: 994
• Species: Drosophila melanogaster
• Sequence 2: NP_001082794.1
• Gene: anpepb / 322533
• ZFINID: ZDB-GENE-030131-1253
• Length: 965
• Species: Danio rerio
• Alignment Length: 1029
• Identity: 356/1029 - (34%)
• Similarity: 543/1029 - (52%)
• Gaps: 116/1029 - (11%)

  Fly     4 TAKLVAIGLGLALTAFTVSTIVLAVQKANLKSDLRDAQEKLDLLEAGYTSTAAPTTASTANPGST 68
            |..:|.|.:|....|..::..|:..|:.:..:::.:.|.         |:|..|||
Zfish    10 TLGIVGIVIGAGAVATIIALSVVYSQEKSKNNEIENQQT---------TTTKGPTT--------- 56

  Fly    69 ASPGSTAEPGSTAEPGSTAEPGSTASPGSTVTPGSTASTSEPGTTASPEKID-YRLPGTLKPTHY 132
                                             ...|:|:.|.|..|.|..| :|||.||.|..|
Zfish    57 ---------------------------------NVPATTNIPTTVPSNEPWDQWRLPQTLSPETY 88

  Fly   133 DLYLFPNIETGE-----FSGQETITITVEEATDQIVLHSLNLNISSVSIMNT--GSDTLEILETT 190
            .:.|:|.::...     |:|..::.....|.||.|::||..|.|...:.:..  |:....|:.|.
Zfish    89 KVTLWPRLQKNAEGLYIFTGDSSVVFRCVENTDLILIHSNKLTIKDSTTLKALGGNPAPNIVSTK 153

  Fly   191 VDAVREFLIFQLNEPLTKGRTVRLHIGFEGSMANKIVGLYSSSYVKEDETRKWIATSKFEPTYAR 255
            :....:::...|:..||.|.:..|:..|.|.:::.:.|.|.|.|..|:...|.:||::.:.|.||
Zfish   154 MYPKTQYMAIWLDRELTAGESYELYTEFVGELSDDLGGFYRSEYYDENGVLKVVATTQMQATDAR 218

  Fly   256 QAFPCFDEPALKAEFTITLVHPSGEDYHALSN----MNVDSSVSQGAFQEVTFAKSVPMSTYLAC 316
            :|||||||||:||.|.|.|:|..|.  .||||    ..:..:|...:..:.|||.:..|||||..
Zfish   219 KAFPCFDEPAMKAVFNIVLLHDPGT--VALSNGVVIEEIPVTVDGISLTKTTFAPTEKMSTYLLA 281

  Fly   317 FIVSDFAYKQVSIDTKGIGETFSMSVYATPEQLD--KVDLAVTIGKGVIEYYIDYFQIAYPLPKL 379
            ||||:|.|.:..:|      ...:.::|..|.:|  :.:.|:::...::.::.:|:..:|||||.
Zfish   282 FIVSEFTYIEQKLD------DLQIRIFARKEAIDANQGEYALSVTGKILRFFEEYYNSSYPLPKS 340

  Fly   380 DMAAIPDFVSGAMEHWGLVTYRETSLLYDEATSSATNKQRIASVIAHEFAHMWFGNLVTMNWWND 444
            |..|:|||.:||||:|||:|||||:|||||..||..||:|:.:|||||.||.|||||||:.||||
Zfish   341 DQIALPDFNAGAMENWGLITYRETALLYDEEMSSNGNKERVVTVIAHELAHQWFGNLVTIRWWND 405

  Fly   445 LWLNEGFASFVEYLGVDAVYPEWKMRDQFTVSTLHSVLTLDGTLGSHPII---QTVENPDQITEI 506
            |||||||||:|||||.|...|.|.::|...::.:|.|..:|....|||:.   :.|:.|:||:|:
Zfish   406 LWLNEGFASYVEYLGADEAEPLWNIKDLIVLNDVHRVFAIDALASSHPLSSKEEDVQRPEQISEV 470

  Fly   507 FDTITYSKGSSLVRMLEDFLGETTFRQAVTNYLNEYKYSTA--------------ETGNFFTEID 557
            ||||:||||:|::|||.:||.|..|.|.:..||..:|::..              |||.
Zfish   471 FDTISYSKGASVLRMLSNFLSEDVFTQGLRTYLEHFKFNNTVYTDLWDHLQMAVDETGT------ 529

  Fly   558 KLELGYNVTEIMLTWTVQMGLPVVTIEKVSDTEYKLTQKRFLSNPNDYDADHEPSEFNYRWSIPI 622
              ||..:|.:||..|.:|||.|||||..|:.   :::|:.||.:|   :...|||||||.|.:||
Zfish   530 --ELPRSVKDIMDRWVLQMGFPVVTINTVTG---QISQEHFLLDP---ETKPEPSEFNYEWFVPI 586

  Fly   623 TYFTSSDSVVQRLWFYHDQSEITVTVPAAVEWIKFNADQVGYYRVNYDTDLWNDLADQLVVQPSA 687
            |: |.::::..:.|.....::.......|.||:..|.:.|||||||||...|..|.:.|.....:
Zfish   587 TW-TKNEAIKPQYWLLQKNTQFDDMKTNANEWVLANINTVGYYRVNYDEQNWERLLNALQTSRES 650

  Fly   688 FGSVDRAHLLNDAFALADSTQLPYATAFELTRYLDKETDYVPWSVAASRL----TSLKRTLYYTS 748
            ...::||.|::|||.||.:..:....|...|.:||.||:|:||..|.:.|    ....|:..|..
Zfish   651 IPVINRAQLIDDAFNLAKAGIIKTTLALRTTEFLDVETEYMPWQSALNNLDYFYLMFDRSEVYGH 715

  Fly   749 TYAKYKKYATALIEPIYTALT-WT-VGEDHLDNRLRVTALSAACSLGLESCLTEAGEQFNAWLAK 811
            ..|..:|..|.|.| .:|.|| |. |.::|.:...:|.||..|||:||::|.......|..|:..
Zfish   716 MQAYIRKQVTPLFE-YFTELTDWQGVPDNHTEQYNQVNALRVACSIGLKNCTDLVTSWFGEWMNN 779

  Fly   812 PEDRP-KADVRETVYYYGIQSVGSQEDWDAVWELFVNESDASEKSKLMYGLSAIQIPWILQRYID 875
            .:..| .|::|.|||...| :.|..|:|:..|::|...|.||||.||...::....||:|.||::
Zfish   780 EDVNPIHANLRSTVYCSAI-AAGGAEEWEFAWKMFEKTSVASEKDKLRAAMACATQPWLLNRYLE 843

  Fly   876 LAWNEEYVRGQDYFTCLTYISANPVGESLVWDYVRENWQRLVDRFGLNERYLGNLIPSITARFST 940
            ...:...:|.||..:.:..|::|..|:||.||:||.||:.:.:::|.......|||..:|.||||
Zfish   844 YTLDANKIRKQDATSTIVSIASNVGGQSLAWDFVRANWEYIFNQYGGGSFSFSNLINGVTKRFST 908

  Fly   941 QTKLEEMEQFFA--KYPEAGAGTAARVRALETVKNNIVWLAENLEGVDAWLDKQ 992
            :.:|:::.||..  ::...|:|:.|..:::|..|.||.|:.:|...|..|...|
Zfish   909 EFELKQLMQFKEDNEHIGFGSGSLAIQQSIERTKANIKWVEQNKADVLQWFKDQ 962

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8773	NP_650273.2	Peptidase_M1	122..515	CDD:279741	166/408 (41%)
		M1_APN_2	130..579	CDD:189008	186/478 (39%)
		ERAP1_C	655..969	CDD:288671	109/322 (34%)
anpepb	NP_001082794.1	Peptidase_M1	78..479	CDD:279741	166/408 (41%)
		M1_APN_2	88..549	CDD:189008	186/476 (39%)
		ERAP1_C	618..940	CDD:288671	109/323 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	51	1.000	Domainoid score	I11553
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D110058at2759
OrthoFinder	1	1.000	-	-		FOG0000044
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100307
Panther	1	1.100	-	-	O	PTHR11533
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X67
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.920