Protein Alignment CG8773 and Lta4h

DIOPT Version :10

• Sequence 1: NP_650273.2
• Gene: CG8773 / 41634
• FlyBaseID: FBgn0038135
• Length: 994
• Species: Drosophila melanogaster
• Sequence 2: NP_001025202.1
• Gene: Lta4h / 299732
• RGDID: 1311333
• Length: 611
• Species: Rattus norvegicus
• Alignment Length: 642
• Identity: 138/642 - (21%)
• Similarity: 235/642 - (36%)
• Gaps: 193/642 - (30%)

  Fly   150 TITITVEEATDQIVLHSLNLNISSVSIMNTGSDTLEILETTVDAVREF----LIFQLNEPLTKGR 210
            |..:||:...|.  |.||.|:...::|.....:..|: :.|:...:.:    :...|...|:|.:
  Rat    38 TAALTVQSQEDN--LRSLTLDTKDLTIEKVVINGQEV-KYTLGESQGYKGSPMEISLPIALSKNQ 99

  Fly   211 TVRLHIGFEGSMANKIVGLYSSSYVKEDETRKWIAT------------SKFEPTYARQAFPCFDE 263
            .|.:.|.||.|              .:....:|:..            |:.:..:.|...||.|.
  Rat   100 EVVIEISFETS--------------PKSSALQWLTPEQTSGKQHPYLFSQCQAIHCRAILPCQDT 150

  Fly   264 PALKAEFTITLVHPSGEDYHALSNMNVDSSVSQGAFQE--------VTFAKSVPMSTYLACFIVS 320
            |::|..:|..:..|  ::..||.     |::..|...:        ..|.:.||:..||...:|.
  Rat   151 PSVKLTYTAEVSVP--KELVALM-----SAIRDGEAPDPEDPSRKIYRFNQRVPIPCYLIALVVG 208

  Fly   321 DFAYKQVSIDTKGIG---------ETFSMSVYATPEQLDKVDLAVTIGKGVIEYYIDYFQIAYPL 376
                   :::::.||         |....|.|...|....:.:|..:|...:  :..|..:..|
  Rat   209 -------ALESRQIGPRTLVWSEKEQVEKSAYEFSETESMLKIAEDLGGPYV--WGQYDLLVLP- 263

  Fly   377 PKLDMAAIPDFVSGAMEHWGLVTYRETSLLYDEATSSATNKQRIASVIAHEFAHMWFGNLVTMNW 441
                    |.|..|.||:..|.....|.|..|::         :::|||||.:|.|.|||||...
  Rat   264 --------PSFPYGGMENPCLTFVTPTLLAGDKS---------LSNVIAHEISHSWTGNLVTNKT 311

  Fly   442 WNDLWLNEGFASFVEYLGVDAVYPEWKMRDQFTVSTLHSVLTLDGTLG-SHPIIQTV-----ENP 500
            |:..|||||...::|......::.| |.|....:.....:.....|.| |||..:.|     .:|
  Rat   312 WDHFWLNEGHTVYLERHICGRLFGE-KFRHFHALGGWGELQNTIKTFGESHPFTKLVVDLKDVDP 375

  Fly   501 DQITEIFDTITYSKGSSLVRMLEDFL-GETTFRQAVTNYLNEYKYSTAET--------GNFFTEI 556
            |   ..:.:|.|.||.:|:..||..| |...|...:..|:.::.|.:..|        .:|..::
  Rat   376 D---VAYSSIPYEKGFALLFYLEQLLGGPEVFLGFLKAYVEKFSYQSVTTDDWKSFLYAHFKDKV 437

  Fly   557 DKL-ELGYNVTEIMLTWTVQMGLPVV------------------------------TIEKVSD-T 589
            |.| ::.:|      .|....|||.|                              :||.:.| :
  Rat   438 DLLNQVDWN------AWLYAPGLPPVKPNYDVTLTNACIALSQRWVTAKEEDLNSFSIEDLKDLS 496

  Fly   590 EYKLTQ----------------KRFLSNPNDYDADHEPSEFNYRWSIPITYFTSSDSVVQRLWFY 638
            .::|.:                || :....:::|.:. ||..:||              .||..
  Rat   497 SHQLNEFLAQVLQKAPLPLGHIKR-MQEVYNFNAINN-SEIRFRW--------------LRLCI- 544

  Fly   639 HDQSEITVTVPAAVEWIKFNADQVGYYRVNYDTDLWNDLADQLVVQPSAFGSVDRAH 695
              ||:....:|.|::.    |.:.|  |:.:...|:.|||        ||   |::|
  Rat   545 --QSKWEEAIPLALKM----ATEQG--RMKFTRPLFKDLA--------AF---DKSH 582

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8773	NP_650273.2	KLF9_13_N-like	<17..118	CDD:425361
		M1_APN-Q_like	130..573	CDD:341064	105/471 (22%)
		ERAP1_C	654..973	CDD:463368	11/42 (26%)
Lta4h	NP_001025202.1	leuko_A4_hydro	6..608	CDD:274120	138/642 (21%)