Protein Alignment CG8773 and R03G8.6

DIOPT Version :9

• Sequence 1: NP_650273.2
• Gene: CG8773 / 41634
• FlyBaseID: FBgn0038135
• Length: 994
• Species: Drosophila melanogaster
• Sequence 2: NP_510175.1
• Gene: R03G8.6 / 181438
• WormBaseID: WBGene00011000
• Length: 747
• Species: Caenorhabditis elegans
• Alignment Length: 617
• Identity: 188/617 - (30%)
• Similarity: 311/617 - (50%)
• Gaps: 60/617 - (9%)

  Fly   121 YRLPGTLKPTHYDLYL---FPNI--ETGE----FSGQETITITVEEATDQIVLHSLNLNISSVSI 176
            ||||..:.|:|||:::   .|..  :..|    |.|...|.:.::|.||::||||.:|||.|.:
 Worm    30 YRLPRHVSPSHYDIHIKTYLPGYGWKADENKITFEGNVNILLDIKETTDKLVLHSSSLNIISAT- 93

  Fly   177 MNTGSDTLEILETTVDAVREFLIFQLNEPLTKGRTVRLHIGFEGSMANKIVGLYSSSYVKEDETR 241
            ..:....:.|....|....:||.|.||..:....:..:.|.|:|.:....:||::::..:||.|.
 Worm    94 FQSDEQNVSISHWNVQTESQFLTFYLNNTVKVQSSAGIQINFQGKVRTDGLGLFATNSTREDGTV 158

  Fly   242 KWIATSKFEPTYARQAFPCFDEPALKAEFTITLVHPSGEDYHALSN-MNVDSSVSQGAFQEVTFA 305
            .....::||..:||...||||||..||.:.::|.||:|..  |||| :.|:|.|:.. ::..|:.
 Worm   159 MTNFATQFETIFARNMIPCFDEPEFKATWNVSLEHPTGST--ALSNGIEVESKVNDD-WKTTTYK 220

  Fly   306 KSVPMSTYLACFIVSDFAYKQVSIDTKGIGETFSMSVYATPEQLDKVDLAVTIGKGVIEYYIDYF 370
            |::.||:|:....:.|..:|: :|...|:    .:.||..|..:|:||.|:.|.:.|:|.:...|
 Worm   221 KTLKMSSYILALFIGDIQFKE-TILNNGV----RIRVYTDPVNIDRVDHALNISRIVLEGFERQF 280

  Fly   371 QIAYPLPKLDMAAIPDFVSGAMEHWGLVTYRETSLLYDEATSSATNKQRIASVIAHEFAHMWFGN 435
            .|.||:.|||..::.:|..||||:||||.:...||:.|        ...:..::.||.||.||||
 Worm   281 GIRYPMEKLDFVSVQNFKFGAMENWGLVIHNAYSLIGD--------PMDVTEIVIHEIAHQWFGN 337

  Fly   436 LVTMNWWNDLWLNEGFASFVEYLGVDAVYPEWKMRDQFTVSTLHSVLTLDGTLGSHPIIQTVENP 500
            ||||.:|:.:||||||||::...|:..:.|::: ||.|.::...:....||.:.    :...:|.
 Worm   338 LVTMKYWDHIWLNEGFASYMTSYGLTFLDPDYQ-RDTFYLNCQFNPQINDGGVS----LNFGKNL 397

  Fly   501 DQITEIFDTITYSKGSSLVRMLEDFLGETTFRQAVTNYLNEYKYSTAETGN----FFTEIDKLEL 561
            ..:.....|: |.||.|.|||||:..|...|.:|:..||.:.:|...:..:    |.|..:.|:.
 Worm   398 SSVMNNAATV-YMKGCSFVRMLENIFGTEYFNEAIKFYLEKNQYDNVDDNDLYEAFRTSSETLDT 461

  Fly   562 G---YNVTEIMLTWTVQMGLPVVTIEKVSDTEY-KLTQKRFLSNPNDYDADHEP----SEFNYRW 618
            .   :::.:....||.|.|.|  ||:..:|... .|||...          :||    :|.:|:|
 Worm   462 NGKPFDIEKFARCWTHQNGFP--TIQVSNDNGIATLTQSHL----------YEPQLMLNECDYKW 514

  Fly   619 SIPITYFTSSDSVVQRLWFYHDQSEITVTVPAAVEWIKFNADQVGYYRVNYDTDLWNDLADQLVV 683
            .|||.|....::.||..|...:.:.:.:   .|.:.:..||:.:|||.|.|...::..:|:|:.:
 Worm   515 DIPIWYQEPGEARVQMAWLNRNSTSLEL---VADDSVIINANSIGYYEVLYSDKMYEKIAEQVAI 576

  Fly   684 QPSAFGSVDRAHLLNDAFALADSTQLPYATAF 715
            ..|.:........|:|.|..:.....|:..||
 Worm   577 NVSRYSVNSLRRTLHDVFRYSRDGLTPFHNAF 608

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8773	NP_650273.2	Peptidase_M1	122..515	CDD:279741	130/402 (32%)
		M1_APN_2	130..579	CDD:189008	147/465 (32%)
		ERAP1_C	655..969	CDD:288671	16/61 (26%)
R03G8.6	NP_510175.1	Peptidase_M1	31..389	CDD:279741	127/375 (34%)
		M1_APN_2	39..482	CDD:189008	147/465 (32%)
		ERAP1_C	548..>622	CDD:288671	16/61 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160164021
Domainoid	1	1.000	101	1.000	Domainoid score	I4343
eggNOG	1	0.900	-	-		E1_COG0308
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D110058at2759
OrthoFinder	1	1.000	-	-		FOG0000044
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11533
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.850