Protein Alignment CG8773 and pam-1

DIOPT Version :10

• Sequence 1: NP_650273.2
• Gene: CG8773 / 41634
• FlyBaseID: FBgn0038135
• Length: 994
• Species: Drosophila melanogaster
• Sequence 2: NP_001023210.1
• Gene: pam-1 / 177528
• WormBaseID: WBGene00003914
• Length: 948
• Species: Caenorhabditis elegans
• Alignment Length: 903
• Identity: 301/903 - (33%)
• Similarity: 462/903 - (51%)
• Gaps: 58/903 - (6%)

  Fly   111 GTTASPEKIDYRLPGTLKPTHYDLYLFPNIETGEFSGQETITITVEEATDQIVLHSLNLNISSVS 175
            |..::..|.: |||...:||||::.|.|.:....|.|..||.:|::||||.:.:|:.:|.|.|||
 Worm    69 GNPSAAVKFE-RLPTFAEPTHYNVRLSPCLNQFSFDGHATIDVTIKEATDVLKVHAQSLLIQSVS 132

  Fly   176 IMNTGSDTLEILETTVDAVREFLIFQLNEPLT-KGRTVRLHIGFEGSMANKIVGLYSSSYVKEDE 239
            ::....|..:.|||:.|.....|..:|  |.| :.:.|:|...|.|.:.:|:.|.|.|.|..::.
 Worm   133 LITQPGDASKSLETSYDDKLNILTIKL--PTTMQPQKVQLDFKFVGELNDKMRGFYRSQYKDKNG 195

  Fly   240 TRKWIATSKFEPTYARQAFPCFDEPALKAEFTITLVHPSGEDY-HALSNMNV--DSSVSQGAFQE 301
            |.|::|:::||.||||.||||||||..||.|.:||   ..|:: .|||||||  ::..:.|..:.
 Worm   196 TEKFLASTQFESTYARYAFPCFDEPIYKATFDVTL---EVENHLTALSNMNVISETPTADGKRKA 257

  Fly   302 VTFAKSVPMSTYLACFIVSDFAYKQVSIDTK-GIGETFSMSVYATPEQLDKVDLAVTIGKGVIEY 365
            ||||.|..||:||..|.|.:..|  :|..|| |:    .|.||..|.:.::...::.:....|::
 Worm   258 VTFATSPKMSSYLVAFAVGELEY--ISAQTKSGV----EMRVYTVPGKKEQGQYSLDLSVKCIDW 316

  Fly   366 YIDYFQIAYPLPKLDMAAIPDFVSGAMEHWGLVTYRETSLLYDEATSSATNKQRIASVIAHEFAH 430
            |.::|.|.|||||.|:.|||||..||||:||||||||.:||.|...:|...|.|:|.|:|||.||
 Worm   317 YNEWFDIKYPLPKCDLIAIPDFSMGAMENWGLVTYREIALLVDPGVTSTRQKSRVALVVAHELAH 381

  Fly   431 MWFGNLVTMNWWNDLWLNEGFASFVEYLGVDAVYPEWKMRDQFTVSTLHSVLTLDGTLGSHPIIQ 495
            :||||||||.||.||||.||||||:||:.|.|..||:|:...|....|.|.:.||....||||..
 Worm   382 LWFGNLVTMKWWTDLWLKEGFASFMEYMFVGANCPEFKIWLHFLNDELASGMGLDALRNSHPIEV 446

  Fly   496 TVENPDQITEIFDTITYSKGSSLVRMLEDFLGETTFRQAVTNYLNEYKYSTAETGNFFTEIDKLE 560
            .::||:::.||:|:|||:|.:|:.|||..:|.|..|::.:..||..::||.|.|.:.:|.:.:..
 Worm   447 EIDNPNELDEIYDSITYAKSNSVNRMLCYYLSEPVFQKGLRLYLKRFQYSNAVTQDLWTALSEAS 511

  Fly   561 LGYNVTEIMLTWTVQMGLPVVTIEKVSDTEYKL---TQKRFLSNPNDYDADHEPSEFNYRWSIPI 622
             |.||.|:|..||.|||.||:.:.:..|...::   .|:||:|     |...:|.  |.:|.:||
 Worm   512 -GQNVNELMSGWTQQMGFPVLKVSQRQDGNNRILTVEQRRFIS-----DGGEDPK--NSQWQVPI 568

  Fly   623 TYF--TSSDSVVQRLWFYHDQSEITVTVPAAVEWIKFNADQVGYYRVNYD----TDLWNDLADQL 681
            |..  :|...|..|......|.|.|:...|..||:|.|:...|:|||.|.    |.:..|:|.:
 Worm   569 TVAVGSSPSDVKARFLLKEKQQEFTIEGVAPGEWVKLNSGTTGFYRVEYSDEMLTAMLPDIASR- 632

  Fly   682 VVQPSAFGSVDRAHLLNDAFALADSTQLPYATAFELTRYLDKETDYVPWSV---AASRLTSLKRT 743
                 ....:||..|:||..||.::.::..|...::.....||.:||.|..   ..|:|.:..|.
 Worm   633 -----RMPVLDRFGLINDLSALLNTGRVSIAQFVQVAASSAKEDEYVVWGAIDEGMSKLLACARE 692

  Fly   744 LYYTSTYAKYKKYATALIEPIYTALTWT--VGEDHLDNRLRVTALSAACSLGLESCLTEAGEQFN 806
            : ...|....|:....:.|.....|.:.  .|||.....||....:.....|.:..:.:..:.||
 Worm   693 M-SEDTLKSAKQLVVKMFEQTGAELGFAEQAGEDSQKMMLRSLVQARLARAGHQPTIDKFTQMFN 756

  Fly   807 AWLAKPEDRP-KADVRETVYYYGIQS-VGSQEDWDAVWELFVNESDASEKSKLMYGLSAIQIPWI 869
            .:|.|  ..| ..|:|  :..:|:.: .|.:|.:|.:..|....:....:.:.|..:|......:
 Worm   757 DFLEK--GTPIHPDIR--LATFGVVARYGGKEGFDKLMNLRETTTFQEIERQTMVAMSQTPEESL 817

  Fly   870 LQRYIDLAWNEEYVRGQDYFTCLTYISANPVGESLVWDYVRENWQRLVDRF-GLNERYLGNLIPS 933
            |.:..:..:.:..||.||.........|..:|:...|.|..|:.:..:|:: |.|.......:..
 Worm   818 LAQLFEYGFEKNKVRPQDQLYLFLGTGATHMGQQYAWKYFCEHIKEFLDKYGGANSSLFQRCLKF 882

  Fly   934 ITARFSTQTKLEEMEQFFAK---YPEAGAGTAARV--RALETVKNNIVWLAENLEGVD 986
            ....|..:.:..|.:.||..   ..:....|.||.  :.:|.::.|...|..|.:.::
 Worm   883 AGESFGNEKRAVEFQDFFCNCNVLSDTDRQTLARPIGQTVEAIRLNARLLESNRQIIE 940

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8773	NP_650273.2	KLF9_13_N-like	<17..118	CDD:425361	1/6 (17%)
		M1_APN-Q_like	130..573	CDD:341064	193/447 (43%)
		ERAP1_C	654..973	CDD:463368	72/335 (21%)
pam-1	NP_001023210.1	M1_APN-Q_like	87..524	CDD:341064	194/448 (43%)
		ERAP1_C	602..927	CDD:463368	72/335 (21%)