Protein Alignment CG8773 and ltah-1.2

DIOPT Version :9

• Sequence 1: NP_650273.2
• Gene: CG8773 / 41634
• FlyBaseID: FBgn0038135
• Length: 994
• Species: Drosophila melanogaster
• Sequence 2: NP_500385.1
• Gene: ltah-1.2 / 177123
• WormBaseID: WBGene00022610
• Length: 625
• Species: Caenorhabditis elegans
• Alignment Length: 628
• Identity: 140/628 - (22%)
• Similarity: 226/628 - (35%)
• Gaps: 165/628 - (26%)

  Fly   147 GQETITITVEEATDQIVLHSLNLNISSVSIMNTGSDTLEILETTVDAVREFLIFQLNEPLTKGRT 211
            ||.|:.........::||...:|:|.||||.....| ..|...........:...|.....|..|
 Worm    42 GQATLRCRCLTDATKLVLDVRDLSIRSVSINGVDCD-FRIAPNVYTFFGSKMSVYLPPQFQKAGT 105

  Fly   212 VRLHIGFEGSMANKIVGLYSSS-------YVKEDET---RKWIATSKFEPTYARQAFPCFDEPAL 266
            :.           ::...|.:|       ::|:::|   |.....|:.:..:||...||.|.|::
 Worm   106 IL-----------QVTVAYGTSPDATALQWMKKEQTADKRMPYLFSQCQAIHARSIVPCMDTPSV 159

  Fly   267 KAEFTITLVHPSGEDYHALSNMNVDSSVSQGAFQEVTFAKSVPMS--TYLACFIVSDFAYKQVSI 329
            |:.:...:..|:|    ....|:.....|:|.....||....|::  :||...:|.....:.:|
 Worm   160 KSTYEAEVTVPTG----MTCLMSAIGQGSKGDDDTTTFFYKQPVAIPSYLIAIVVGCLEKRDIS- 219

  Fly   330 DTKGIGETFSMSVYATPEQLDKV--DLAVT----------IGKGVIEYYIDYFQIAYPLPKLDMA 382
                    ...:|:|.|..:||.  :.|.|          .||             |...:.||.
 Worm   220 --------DRCAVWAEPSVVDKAHWEFAETEDILASAEEIAGK-------------YIWGRYDMV 263

  Fly   383 AI-PDFVSGAMEHWGLVTYRETSLLYDEATSSATNKQRIASVIAHEFAHMWFGNLVTMNWWNDLW 446
            .: |.|..|.||:..|.....|.:..|.:         :.||||||.||.|.|||||.:.|...|
 Worm   264 CLPPSFPFGGMENPCLTFLTPTLIAGDRS---------LVSVIAHEIAHSWSGNLVTNSSWEHFW 319

  Fly   447 LNEGFASFVE-----------------YLG-----VDAVYPEWKMRDQFTVSTLHSVLTLDGTLG 489
            |||||..|:|                 :.|     :.|||.::....|||
 Worm   320 LNEGFTMFIERKICGRLVSEDYRQFMAFNGWTNSLIPAVYEQFTPTHQFT--------------- 369

  Fly   490 SHPIIQTVENPDQITEIFDTITYSKGSSLVRMLEDFLG-------------ETTFRQAVTNYL-- 539
              .:||...|.|. ...|..:.|.|||:|:..||..||             :|...||:.::.
 Worm   370 --KLIQDHTNVDP-DVAFSCVPYEKGSALLFYLEQKLGGSEIFEAYLKDYLKTFAHQAIDSWQWK 431

  Fly   540 -NEYKY-----STAETGNF---FTEI----DKLELGYNVTE----IMLTWTVQMGLPVVTIEKVS 587
             :.|||     ...:|.||   |..:    :|...|.::.|    ::..|   :.....|:..::
 Worm   432 DHLYKYFADQKEVLDTVNFDLWFNGVGMPPEKPNYGQSMVEACEVLLKKW---LAADESTVGDIT 493

  Fly   588 DTEY----KLTQKRFLSNPNDYDADHEPSEFNYRWSIPITYFTSSDSVVQRL---WF-YHDQSEI 644
            ..:|    .|.|...||..    ..|:|...:|:.......:..:||....|   |. ...:|:.
 Worm   494 SEDYYAMQPLQQIELLSQL----WQHDPPIEHYKLDALNKLYKLNDSQNSELLLNWLRLCIKSKW 554

  Fly   645 TVTVPAAVEWIKFNADQVGYYRVNYDTDLWNDLADQLVVQPSA 687
            ...:|.|::::....      |:.:...::.|||...:....|
 Worm   555 EECIPKALDFVNSQG------RLKFCRPIYRDLAQWPIANKKA 591

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8773	NP_650273.2	Peptidase_M1	122..515	CDD:279741	97/414 (23%)
		M1_APN_2	130..579	CDD:189008	119/510 (23%)
		ERAP1_C	655..969	CDD:288671	5/33 (15%)
ltah-1.2	NP_500385.1	M1_LTA4H	12..455	CDD:341062	114/477 (24%)
		Leuk-A4-hydro_C	500..614	CDD:378127	19/102 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910