Protein Alignment CG8773 and Y67D8C.9

DIOPT Version :9

• Sequence 1: NP_650273.2
• Gene: CG8773 / 41634
• FlyBaseID: FBgn0038135
• Length: 994
• Species: Drosophila melanogaster
• Sequence 2: NP_001122826.1
• Gene: Y67D8C.9 / 177088
• WormBaseID: WBGene00022073
• Length: 1144
• Species: Caenorhabditis elegans
• Alignment Length: 1170
• Identity: 288/1170 - (24%)
• Similarity: 442/1170 - (37%)
• Gaps: 298/1170 - (25%)

  Fly     6 KLVAIGLGLALTAFTVSTIVLAV----------QKANLKSDLRDAQEKLDLLEAGY-TSTAAPTT 59
            |.:|:   :.|.|..:..|:.|:          ||.:.::.|.....:..|||..| ||||.|.:
 Worm    44 KCIAV---ILLHAIFLLAILAALIIGHWISEENQKLSNRTMLNITLAEAYLLEGIYTTSTATPES 105

  Fly    60 ASTAN----PGSTASPGSTAE--PGSTAEPGSTAEPGSTASPGSTVTPGSTAS-------TSEPG 111
            .|..:    ..|:|:.|.:.:  |....|.....|.....:......|.:...       .:...
 Worm   106 LSHHHTHLLTTSSAALGQSKKKTPPRVVERLIPLEKKRNFTISDVFPPPADGGFGIAEQLHAVRA 170

  Fly   112 TTASPEKIDYRLPGTLKPTHYDLYL-FPNIETGEFSGQETITITVE----EATDQIVLHSLNLNI 171
            ...|.:.:...||..:.|.||||.| |...:|..|. :..|:|.:|    ...|:|..| |..||
 Worm   171 NKLSTDALLVPLPLYILPYHYDLQLDFSQFDTHLFI-RANISIHLESYGNSTEDEIQFH-LGPNI 233

  Fly   172 SSVSIMNTGSDTLEILETTV--DAVREFLIFQLNEPLTKGRTVRLHIGFEGSMANKIV-GLYSSS 233
             .:..|....|..:....|.  :..::.....|.:||.||:.: |.:.:..::.::.| |:..|.
 Worm   234 -KMERMRLRKDGKKFYAKTFKREESKKLGRISLRDPLQKGKYI-LEMTYNMTICDEDVDGVRCSL 296

  Fly   234 YVKEDETRKWIA-TSKFEPTYARQAFPCFDEPALKAEFTITLVHPSGEDYHALSNM----NVDSS 293
            ..:.:.:.|..: |:|||||.||..|||:|||.:||.|.|::.|  .:.|..||||    :.|..
 Worm   297 DNQTNSSLKATSFTTKFEPTLARAFFPCWDEPGVKATFNISVRH--NKKYTVLSNMPPVESHDHK 359

  Fly   294 VSQGAFQEVTFAKSVPMSTYLACFIVSDFAYKQVSIDTKGIGETFSMSVYATPEQLDKVDLAVTI 358
            ..:..|:...|..:.||||||..|.:.:|. |..|...:||    .::|:..||.:..:...:..
 Worm   360 SWEDQFKTTVFQTTPPMSTYLLAFAIGEFV-KLESRTERGI----PVTVWTYPEDVMSMKFTLEY 419

  Fly   359 GKGVIEYYIDYFQIAYPLPKLDMAAIPDFVSGAMEHWGLVTYRETSLLY--------DEATSSAT 415
            ...:.:...|..:|.|||||:|:.|..:|..|.||:||||.:...|:.|        :|......
 Worm   420 APVIFDRLEDALEIPYPLPKVDLIAARNFHVGGMENWGLVVFEFASIAYTPPITDHVNETVDRMY 484

  Fly   416 NKQRIASVIAHEFAHMWFGNLVTMNWWNDLWLNEGFASFVEYLGVDAVYPEWKMRDQFTVSTLHS 480
            |:.||..:||||.||.||||||||..|::|:||||||:|..|   :.:..|..:..||......:
 Worm   485 NEFRIGKLIAHEAAHQWFGNLVTMRDWSELFLNEGFATFYVY---EMMSTERPVTAQFEYYDSLA 546

  Fly   481 VLTLDGTLGSH--PIIQTVENPDQITEIF-DTITYSKGSSLVRMLEDFLGETTFRQAVTNYLNEY 542
            .|.|..:...|  .:::.:....|:...| .|..|:||..|:|||.|.:.:..|:.||..||.:.
 Worm   547 SLILAQSEEDHRLSLVRELATESQVESSFHPTNLYTKGCVLIRMLRDLVSDFDFKAAVRRYLRKN 611

  Fly   543 KYSTAETGNFF----------TEIDKLELGYNVTEIMLTWTVQMGLPVVTIEKVSDTEYKLTQKR 597
            .|.:....:.|          .|.:||      :.::..|.|..|:|.:|:.:..|.|.....:|
 Worm   612 AYRSVSRDDLFASLPAYADHGAEQEKL------SHVLEGWFVNEGIPEITLIRNYDNEMMTISQR 670

  Fly   598 ------------------------------------------FLSNPNDYDADHEP--------- 611
                                                      ::....|....|.|
 Worm   671 KTVHHEYRSFLKDRKASASVRYRGSRSAEDGSTLFDDALFDGYIEKKKDRRRKHRPIRRKTSTPP 735

  Fly   612 --SEFNYR---------------WSIPITYF-----TSSDSVVQRLWFYH-----DQSEITVTVP 649
              |..:.|               |:|||||.     ||...|::..|..:     ..:||:....
 Worm   736 SISPISRRDELRKPRRVGASQDLWTIPITYMFGSLKTSEGQVIREFWLKNRTVSFGDAEISPNQA 800

  Fly   650 AAV--EWIKFNADQVGYYRVNYDTDLWNDLADQLVVQPSAFGSVDRAHLLNDAFALADSTQLPYA 712
            ..|  || |:.      ||||||...|..||..|...........|..|:.||.....::..|:.
 Worm   801 VLVNPEW-KYP------YRVNYDLLNWKLLARTLHQNHLEINEKSRMQLILDAEYFLSNSVNPHL 858

  Fly   713 TAFELTRYLDKET---------DYVPWSVAASRLTSL-KRTLYYTSTYAKYKKYATALIEPIYTA 767
            ..: |..||..||         |.|...:...:.|.| |..|.|              .||:.:.
 Worm   859 YLY-LLGYLAHETKMEVMLFGIDAVYKFIDVYKATQLNKAILVY--------------FEPVISQ 908

  Fly   768 LTWTVGEDHLDNRLRVTALSAA----------------CSLGLESCLTEAGEQFNAWLAKPEDRP 816
            :      |||.|..:|.|.:|:                |:.||.||..:...|  .|...|::..
 Worm   909 M------DHLLNESQVDAETASLWLVRPERLAKLYQMRCAAGLSSCKNDYYTQ--RWSRSPDEWT 965

  Fly   817 KADVRETVYYY---------------------GIQSVGSQEDWDAVWELFVNESDASEKSKLM-- 858
            : ||.:.|...                     .:||.|      |.|.|.|..:..|...||:
 Worm   966 E-DVHKQVTAVCHQLFTNTPDEVKTVQDLLDSRLQSSG------AKWALTVQLAACSHDQKLLRR 1023

  Fly   859 -------------YGLSAIQIPWIL------QRYIDLAWNEEYVRGQDYFTCLTYISAN-----P 899
                         |. ||:|..:.|      ::|:   |.|  :.....|......|.|     |
 Worm  1024 TARAIVSTKNAVVYA-SALQSDFSLHYNPTFRKYL---WAE--IAKMSTFEKTALFSTNSTDILP 1082

  Fly   900 VGESLVW-----DYVRE------NWQRLVD-RFGLNERYLGNLIPSITARFSTQTKLEEMEQFFA 952
            ....|:.     |.:::      ||..|:. .|...||||         .:.:......:.||||
 Worm  1083 ASRILLHSVKTIDELQQIRGLLTNWGPLLSLHFEYLERYL---------LWVSSVSQGVLHQFFA 1138

  Fly   953  952
             Worm  1139  1138

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8773	NP_650273.2	Peptidase_M1	122..515	CDD:279741	132/416 (32%)
		M1_APN_2	130..579	CDD:189008	149/482 (31%)
		ERAP1_C	655..969	CDD:288671	84/383 (22%)
Y67D8C.9	NP_001122826.1	Peptidase_M1	182..584	CDD:279741	132/415 (32%)
		M1_APN_2	190..652	CDD:189008	149/481 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D110058at2759
OrthoFinder	1	1.000	-	-		FOG0000044
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11533
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.020