Protein Alignment CG8773 and T16G12.1

DIOPT Version :10

• Sequence 1: NP_650273.2
• Gene: CG8773 / 41634
• FlyBaseID: FBgn0038135
• Length: 994
• Species: Drosophila melanogaster
• Sequence 2: NP_499230.2
• Gene: T16G12.1 / 176416
• WormBaseID: WBGene00011803
• Length: 1890
• Species: Caenorhabditis elegans
• Alignment Length: 958
• Identity: 226/958 - (23%)
• Similarity: 392/958 - (40%)
• Gaps: 175/958 - (18%)

  Fly   131 HYDLYLFPNI---------ETGEFSGQETITITVEEATDQIVLHSLNLNISSVSI---------- 176
            :|.|.|..||         |...||...|:|..:...|..|.:::..|....|||
 Worm  1004 YYKLDLQVNIPGSGPYQWYENMTFSATSTVTFQLVSPTSSITINAHRLMFDPVSIRLYNENDENA 1068

  Fly   177 --------------MNTGSDTLEILETTVDAVREFLIFQLNEPLTKGRTVRLHIGFEGSM-ANKI 226
                          .:.|:.|:..:..||....::.:|               |.:.|.: .|..
 Worm  1069 HTPIPIDFSKVMKDYDKGTVTIPTMNNTVLYPNQYSLF---------------IEYTGFIFQNPD 1118

  Fly   227 VGLYSSSYVKEDETRK-WIATSKFE--PTYARQAFPCFDEPALKAEFTITLVHPSGEDYHALSN- 287
            .|..|::|:.....|| ||.|:.||  |. ||...||:|||:.|.:|.:::.||:  |..||||
 Worm  1119 EGDASNTYLGGLNNRKGWIFTTDFEGGPG-ARSLLPCWDEPSYKGQFEVSVFHPT--DMIALSNE 1180

  Fly   288 MNVDSSVSQGAFQEVTFAKSVPMSTYLACFIVSDFAYKQVSIDTKGIGETFSMSVYATPEQLDKV 352
            :::..::....:....||.:..|||||....|..|:.......|   |....:..::..||..:.
 Worm  1181 VDIQRTIYDNGWTTTKFATTNQMSTYLLALCVGHFSNLATVTRT---GVLTRVWTWSGMEQYGEF 1242

  Fly   353 DLAVTIGKGVIEYYIDYFQIAYPLPKLDMAAIPDFV--SGAMEHWGLVTYRETSLLYDEATSSAT 415
            .|.||  .|.|::..:||...:||.|||:.|:|::.  :||||:|||:....:..::|...::..
 Worm  1243 ALNVT--AGTIDFMENYFSYDFPLKKLDVMALPEYTMNAGAMENWGLIIGEYSLFMFDPDYATTR 1305

  Fly   416 NKQRIASVIAHEFAHMWFGNLVTMNWWNDLWLNEGFASFVEYLGVDAVYPEWKM----RDQFTVS 476
            :...:|...|||..|.|||::||::||||::||||||.:....|:|..:||...    .::|.::
 Worm  1306 DITEVAETTAHEVVHQWFGDIVTLDWWNDIFLNEGFAQYWFANGIDNTFPEQHAYSIDYNRFYMN 1370

  Fly   477 TLHSVLTLDGTLG-SHPIIQTVENPDQITEIFDTITYSKGSSLVRMLEDFLGETTFRQAVTNYLN 540
              |..|..|...| :.|:|.  :.|    .:|....|.|||:|:.:|.:.|....|::.:::||.
 Worm  1371 --HIALKYDCIPGVAKPVIS--DTP----PVFGIEPYYKGSALLNLLNNVLTPAVFQEGLSSYLT 1427

  Fly   541 EYKYSTAETGNFFTEIDKLELGYNVTE----------IMLTWTVQMGLPVVTIEKVSDTEYKLTQ 595
            :|.|..|...|.:|.:......:|:|:          .|..:|:|...|::|:.....:..:..|
 Worm  1428 QYGYVNASPRNLWTSLTVAAQRHNITDWNGQPLDVSSFMDPYTLQTSYPIITLTLRGTSTVQANQ 1492

  Fly   596 KRFLSNPNDYDADHEPSEFNYRWSIPITYFTSSDSVVQRLWF--YHDQSEITVTVPAAVEWIKFN 658
            :..:|:..             .|::|:  ||.:...:...||  :...::.|...|....:...|
 Worm  1493 QSCMSDET-------------LWNVPL--FTQTPGALDFNWFVNFTGGNDATWLRPLPTGYRVDN 1542

  Fly   659 ADQVGYYRVNYDTDLWNDLADQLVVQPSAFGSVDRAHLLNDAFALADSTQLPYATAFELTRYLDK 723
            |....:.|:|||...|..:..||:...:...|..||.||:||.....|.:.......:||.||..
 Worm  1543 AGSTSFARINYDDKSWYSIQAQLLSNMNTMSSTTRAMLLDDANFFYQSGRWEMTKFLDLTLYLVN 1607

  Fly   724 ETDYVPWSVAASRLTSLKRTLYYTSTYAKYKKYATALIEPIYTALTWTV----GEDHL------D 778
            |....||..|....|.:.....|.......:.|...:.:...:...|..    ..|.:      .
 Worm  1608 EDSLAPWEQAIEFFTEMLNRFQYQPEIDTVRNYVIQITKNAVSKFQWNTNGLWANDRIVQLLVNV 1672

  Fly   779 NRLRVTALSAACSLGLESCLTEAGEQFNAWLAK---------------PEDRPKADVRETVYYYG 828
            |.|.|...|...:|.|          ||.::.|               |      ::|:..|.||
 Worm  1673 NNLAVNRQSRQVALTL----------FNNFVLKCKYSLSGTGKCSGIHP------NLRQPTYCYG 1721

  Fly   829 IQSVGSQEDWDAV---WELFVNESD--ASEKSKLMYGLSAIQIPWILQRYIDLAWNEEYVR---G 885
            ::...:.:|:..|   :..||..:.  .::.|.|:..|..:|         :|...:..:|   .
 Worm  1722 LRQSNNIDDFTTVNNLYSWFVQNAGYLQTDGSNLLNALGCVQ---------NLDLQKTMLRSILS 1777

  Fly   886 QDY-FTCLTYISANPVGESLVWDYVRENWQRLVDR---FGLNERYLGNLIPSITARFSTQTKLEE 946
            .|| .:.|..|:.:.....::::::.:|.|.:::.   |.|       .:.::...:||..:||.
 Worm  1778 GDYPPSLLNSIAVHDDSSDVLYNFLLDNTQDILNAPFDFSL-------YVKAMFQNWSTSNQLEL 1835

  Fly   947 MEQF--FAKYPEAGAGTA-ARVRALETVKNNIVWLAENLEGVDAWLDK 991
            .:.|  .:.|....|... ...:.:.||.:|..|:.........|:.|
 Worm  1836 AKDFQNSSNYNLLNAAQKNIYKQGILTVNSNANWMLIYKTPFLEWIQK 1883

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8773	NP_650273.2	KLF9_13_N-like	<17..118	CDD:425361
		M1_APN-Q_like	130..573	CDD:341064	137/496 (28%)
		ERAP1_C	654..973	CDD:463368	71/358 (20%)
T16G12.1	NP_499230.2	M1_APN-Q_like	90..544	CDD:341064
		ERAP1_C	639..931	CDD:463368
		M1_APN-Q_like	1005..1471	CDD:341064	137/496 (28%)
		ERAP1_C	1542..1839	CDD:463368	66/328 (20%)