Protein Alignment CG8773 and mnp-1

DIOPT Version :9

• Sequence 1: NP_650273.2
• Gene: CG8773 / 41634
• FlyBaseID: FBgn0038135
• Length: 994
• Species: Drosophila melanogaster
• Sequence 2: NP_497878.1
• Gene: mnp-1 / 175564
• WormBaseID: WBGene00007139
• Length: 781
• Species: Caenorhabditis elegans
• Alignment Length: 762
• Identity: 146/762 - (19%)
• Similarity: 284/762 - (37%)
• Gaps: 192/762 - (25%)

  Fly     7 LVAIGLGLALTAFTVSTIVLAVQKAN-LKSDLRDAQEKLDLLEAGYTSTAAPTTASTANPG---- 66
            |:|:.:|:.|.|..::.:.|..:..: ...|.::|.| :.|......:.:..||.|...|.
 Worm    21 LIAVIIGIILCAGVITFLTLFNKNGDGPDMDWQNATE-VPLTTTSKATVSTTTTQSATTPSTTTT 84

  Fly    67 -----STASPGSTAEPGSTAEPGSTAEPGSTASPGSTVT-------PGSTASTSEPGT------- 112
                 :|.:.|:..|....:|..::..|.:.|.|.:|.|       |...||..:..|
 Worm    85 RIEETTTTTSGAFDESVKNSEASTSTIPTTEAVPTTTATDAPEIVMPVDVASILKDKTKDFEIVE 149

  Fly   113 --------------TASPEKIDYRLPGTLKPTHYDLYL-FPNIETGEFSGQETITITVEEATDQI 162
                          :.||...|   |...:|.||.|.: ..::......|...:..:.::....|
 Worm   150 KCAEIQALPVSCTPSQSPLTSD---PSKFQPIHYVLNITIRDVRKPVLEGHMQLFASTKDQVQAI 211

  Fly   163 VLHSLNL----NISSVSIM--NTGSDTLEILETTVDAVREFLIFQLNEPLTKGRTVRLHIGFEGS 221
            .|||:.:    |...:.::  |||.   .|..:.|..:.:.:..:|.:.::.|  |.|.:..:|
 Worm   212 SLHSVKIHNLENRDRIHVVNCNTGE---TICVSRVHQIDDLIHLELAQSISSG--VNLRVDIDG- 270

  Fly   222 MANKIVGLYSSSYV-KEDETRKW----IATSKFEPTYARQAFPCFDEPALKAEFTITLVHPSGED 281
                .:...|..:| |:..|.||    :..|.||||.||..||.||....|:.|.:.|.|  |..
 Worm   271 ----FISADSGPHVFKQIPTAKWRVPQMIGSVFEPTSARHVFPSFDLHNQKSTFNLCLNH--GPS 329

  Fly   282 YHALSNMNVDSSVSQGAFQEVTFAKSVPMSTYLACFI----VSDFAYKQVSIDTKGIGETFSMSV 342
            ..|::|..::.:||.....  .|.|:||:......|:    .:...|...::|          ..
 Worm   330 MSAIANSLINPNVSTSGIS--CFEKTVPLIAQQLSFVAFEKTNPLFYNTTTMD----------GA 382

  Fly   343 YATPEQLDKVDLAVTI-GKGVIEYYIDYFQI-------------AYPLPKLDMAAIPDFVSGAME 393
            |     |.::|:...: .|...:|...:.::             :|||.:|::...|  |.....
 Worm   383 Y-----LPEIDMIFNLNAKNFKQYEWIHSEVSKVMALMSKWSGFSYPLTRLEIVVAP--VQAGHS 440

  Fly   394 HWGLVTYRETSLLYDEATSSATNKQRIASVIAHEFAHMWFGNLVTMNWWNDLWLNEGFASFVEYL 458
            ..|::|....::.|.:.||  |::..|..||.     .|...:||..          ...|.:.|
 Worm   441 ALGVITLPAQAIAYQKHTS--THETLIKEVIG-----QWMEGVVTTE----------HTCFEKAL 488

  Fly   459 GVDAVYPEWKMRDQ---------FTVSTLHSVLTLDGTLGSHPIIQTVENPD------QITEIFD 508
               ..|.|||:.::         ..||.:.. ..|:.|..|..:::.:::..      :..|:|.
 Worm   489 ---IAYVEWKINEELQIVKKTRKMEVSKIRP-RNLNETADSVRVLRQIKSQSSNLCSPRFVEVFY 549

  Fly   509 TITYSKGSSLVRMLEDFLGETTFRQAVTNYLNEYKYSTAETGNFFTEID-----KLELGYNVTEI 568
            |            |::..|:.|....:....:::.:|||...::.:..:     :.|.|    .:
 Worm   550 T------------LDETYGQETVIGMIRVIFDKFAFSTATISDWASAAETATGGRPEAG----AL 598

  Fly   569 MLTW---TVQMGLPVV-TIEKVSDTEY-KLTQKRFLSNPNDYDADHEPSEFNYRWSIPITYFTSS 628
            :..|   :..:..||: .:...:..|: :||::                    .|::|:....|:
 Worm   599 IHQWYRPSSTISRPVLRAVVSSNSVEFNQLTEE--------------------TWTVPLEISGSA 643

  Fly   629 DSVVQRLWFYHDQSEITVTVP-AAVEWIKFNADQVGYYRVNYDTDLW 674
            .:.:..:      ||....:| .:.:::..:|.:..:..|.||.|.:
 Worm   644 GTQLAVI------SEKKQAIPFVSSDYVVVDAGRKSHAFVVYDADTY 684

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8773	NP_650273.2	Peptidase_M1	122..515	CDD:279741	91/437 (21%)
		M1_APN_2	130..579	CDD:189008	98/501 (20%)
		ERAP1_C	655..969	CDD:288671	5/20 (25%)
mnp-1	NP_497878.1	Peptidase_M1	172..556	CDD:279741	92/447 (21%)
		GluZincin	<294..>480	CDD:301352	50/213 (23%)
		GluZincin	<547..602	CDD:301352	10/70 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0308
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11533
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910