Protein Alignment CG8773 and LOC1273751

DIOPT Version :10

• Sequence 1: NP_650273.2
• Gene: CG8773 / 41634
• FlyBaseID: FBgn0038135
• Length: 994
• Species: Drosophila melanogaster
• Sequence 2: XP_003436384.2
• Gene: LOC1273751 / 1273751
• VectorBaseID: AGAMI1_009321
• Length: 1054
• Species: Anopheles gambiae
• Alignment Length: 1037
• Identity: 471/1037 - (45%)
• Similarity: 631/1037 - (60%)
• Gaps: 78/1037 - (7%)

  Fly     1 MIVTAKLVAIGLGLALTAFTVSTIVLAVQKANLKSDLRDAQEKLDLLEAGYTSTAAPTTAST--- 62
            :::.:.|.|......|:...::.:||..:  ||.:|            ||  |.:..|.||.
Mosquito    41 IVILSLLAACAFLFVLSLCLLTALVLVGR--NLSAD------------AG--SHSQLTVASDDKQ 89

  Fly    63 ---ANPGSTASPGSTAEPGSTAEPGSTAEPGSTASPGSTVTPGSTASTS---------EPGT--- 112
               .|.......|...:.....|...|.||....|  :...|.|..:||         .|||
Mosquito    90 HLFINNNHIDHDGDDGDDAGEEERERTNEPQYNRS--TIFLPNSVFNTSAAPPPPVAVSPGTGPT 152

  Fly   113 ----------TASPEKIDYRLPGTLKPTHYDLYLFPNIETGEFSGQETITITVEEATDQIVLHSL 167
                      |...|::.:|||..::|.||:|:|.|:::...|||:..|.:.|.|:|:.|||||.
Mosquito   153 GRMNRVFKMGTQVAERLGFRLPRHIRPVHYELWLQPDLQRETFSGRVGIELNVSESTNYIVLHSK 217

  Fly   168 NLNISSVSI--MNTGSDTLEILETTVDAVREFLIFQLNEPLTKGRTVRLHIGFEGSMANKIVGLY 230
            .|:|:...:  :.||.:.:.|.........|:.:.:....:..| ..||.:.|.||:|::|:|.|
Mosquito   218 KLSITETVLRTLGTGPEEVTIARAYELPEHEYWVIETQGEIGAG-AYRLSVQFNGSLADRIIGFY 281

  Fly   231 SSSYVKEDETR-KWIATSKFEPTYARQAFPCFDEPALKAEFTITLVHPSGEDYHALSNMNVDSSV 294
            ||.|:.:...| :.|||||||||:|||||||||||.||||:||.:|||||:.|.|||||||..:|
Mosquito   282 SSKYLDKTTNRTRTIATSKFEPTFARQAFPCFDEPHLKAEYTIHMVHPSGDGYAALSNMNVKETV 346

  Fly   295 S---QGAFQEVTFAKSVPMSTYLACFIVSDFAYKQVSIDTKGIGETFSMSVYATPEQLDKVDLAV 356
            :   .......||.:||.|||||..||||||.:::|.|..:. |.:|.:.|||||.|.:....|:
Mosquito   347 ADKPSAGLSTTTFERSVSMSTYLVVFIVSDFLHQEVLIVPEH-GSSFPLRVYATPFQQENTAYAL 410

  Fly   357 TIGKGVIEYYIDYFQIAYPLPKLDMAAIPDFVSGAMEHWGLVTYRETSLLYDEATSSATNKQRIA 421
            ...:.:|:||:.||.||||||||||||||||||||||.||||||||||:||:..|||..||||:|
Mosquito   411 ATARTIIQYYVKYFGIAYPLPKLDMAAIPDFVSGAMETWGLVTYRETSILYNSVTSSTANKQRVA 475

  Fly   422 SVIAHEFAHMWFGNLVTMNWWNDLWLNEGFASFVEYLGVDAVYPEWKMRDQFTVSTLHSVLTLDG 486
            .|||||.|||||||||||.|||:|||||||||::||.|:||.:|:|.:.:||.:..||.||.||.
Mosquito   476 GVIAHELAHMWFGNLVTMKWWNELWLNEGFASYIEYKGMDAAHPDWGIEEQFIIDDLHGVLNLDA 540

  Fly   487 TLGSHPIIQTVENPDQITEIFDTITYSKGSSLVRMLEDFLGETTFRQAVTNYLNEYKYSTAETGN 551
            |||||||:.:||||:||||||||||||||:|::||||||:....|:|.|..||.:..|:.:.:.:
Mosquito   541 TLGSHPIVMSVENPNQITEIFDTITYSKGASVIRMLEDFVTPPVFQQGVKRYLEKLAYANSVSED 605

  Fly   552 FFTEIDKLELGYNVTEIMLTWTVQMGLPVVTIEKVSDTEYKLTQKRFLSNPNDYDADH-EPSEFN 615
            ...|:|:|....:||.:|.|:|.|.||||||:.: :..:|.|.|:|||:   |.||:. |.|.:.
Mosquito   606 LMRELDELVPDVSVTGVMDTFTRQKGLPVVTVAE-NALQYVLRQQRFLA---DQDANETEESPYG 666

  Fly   616 YRWSIPITYFTSSD----SVVQRLWFYHDQS--EITVTVPAAVEWIKFNADQVGYYRVNYDTDLW 674
            |||.|||||..|:|    :..:|:||.:|.|  |:.:..||...|||.|..|:|||||||...:|
Mosquito   667 YRWYIPITYLASTDDPATAAPRRIWFPNDASRPELVIDKPAGSSWIKLNYRQIGYYRVNYPIAMW 731

  Fly   675 NDLADQLVVQPSAFGSVDRAHLLNDAFALADSTQLPYATAFELTRYLDKETDYVPWSVAASRLTS 739
            ....:.|..:.:.|...||..||||||||||::.|.|..|.||||||..||:|||||..||:|.:
Mosquito   732 QQFGEALRKEVNTFTIGDRTGLLNDAFALADASLLAYNHALELTRYLSGETEYVPWSAIASKLKN 796

  Fly   740 LKRTLYYTSTYAKYKKYATALIEPIYTALTWTVGED--HLDNRLRVTALSAACSLGLESCLTEAG 802
            ::..||...:|.....|...|::....::.|.|..:  |:.|.||.|.|..|||.|..:||.||.
Mosquito   797 IRNLLYNYQSYDDITTYTQTLVDAAVKSVGWDVPAEGGHMTNLLRTTILDLACSFGHPACLEEAS 861

  Fly   803 EQFNAWL-----AKPEDRPKADVRETVYYYGIQSVGSQEDWDAVWELFVNESDASEKSKLMYGLS 862
            :||..||     ..|      |:|..||.|||||..:..|||.|.|.|..|:||:||:|||..|:
Mosquito   862 KQFRGWLNDGAVIHP------DLRSVVYTYGIQSGVTVADWDKVLERFRQENDANEKTKLMVALA 920

  Fly   863 AIQIPWILQRYIDLAWNEEYVRGQDYFTCLTYISANPVGESLVWDYVRENWQRLVDRFGLNERYL 927
            :......::|::||:|:...||.||..:|:.||:||..||...|::|||||.|||.|||:.||.|
Mosquito   921 SYPDQRTMRRFLDLSWDTALVRTQDQLSCIQYIAANRAGEQAAWEHVRENWPRLVARFGIGERNL 985

  Fly   928 GNLIPSITARFSTQTKLEEMEQFFAKYPEAGAGTAARVRALETVKNNIVWLAENLEGVDAWL 989
            |.:|||:|.||:||.:|.|:|.|||:|||:|||..||.:|||.::|||.||..|...|.|||
Mosquito   986 GRMIPSVTGRFTTQARLTELEDFFARYPESGAGATARRQALENIQNNISWLERNEANVAAWL 1047

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8773	NP_650273.2	KLF9_13_N-like	<17..118	CDD:425361	26/128 (20%)
		M1_APN-Q_like	130..573	CDD:341064	238/448 (53%)
		ERAP1_C	654..973	CDD:463368	152/325 (47%)
LOC1273751	XP_003436384.2	None