Protein Alignment CG8773 and trhde.1

DIOPT Version :10

• Sequence 1: NP_650273.2
• Gene: CG8773 / 41634
• FlyBaseID: FBgn0038135
• Length: 994
• Species: Drosophila melanogaster
• Sequence 2: XP_001345457.3
• Gene: trhde.1 / 100006808
• ZFINID: ZDB-GENE-170406-2
• Length: 994
• Species: Danio rerio
• Alignment Length: 1025
• Identity: 315/1025 - (30%)
• Similarity: 504/1025 - (49%)
• Gaps: 98/1025 - (9%)

  Fly     2 IVTAKLVAIGLGLA-LTAFTVSTIVLAVQKANLKSDLRDAQEKLDLLEAGYTSTAAPTTASTANP 65
            |...|.:.:|..:: ||...|:.|.:.                   |...:...||.::.:.|..
Zfish    33 ITVHKRLVLGFAISILTLIIVTAIAIT-------------------LSVSFERCAAESSGALAAN 78

  Fly    66 GSTASPGSTAEPGSTAEPGSTAEPGSTASPGSTVTPGSTASTSEPGTTASPEKIDYRLPGTLKPT 130
            ||:.|....:..|:.:.                       ..||.|  ..|.: ..|||.||:|.
Zfish    79 GSSNSKWKQSRDGNISH-----------------------RDSEDG--QQPWR-HLRLPATLRPR 117

  Fly   131 HYDLYLFPNIETGEFSGQETITITVEEATDQIVLHSLNLNISSVSIMNTG--SDTLEILETTVDA 193
            ||||.|..::|...|||:..|......:|..|||||..|.:..|.:.:..  :..:.|.......
Zfish   118 HYDLRLTVHMENFSFSGEVNIEFECVNSTKLIVLHSDRLELDKVLVFSDSKKAGAMRIQRRFHYQ 182

  Fly   194 VREFLIFQLNEPLTKGRTVRLHIGFEGSMANKIVGLYSSSYVKEDETRKWIATSKFEPTYARQAF 258
            .::..:..|:..:...||.:::|.|...:.::::|.:.|||:...| |:::|.::|.||:||:||
Zfish   183 PKQVYVIALHREMKPLRTYKINITFTAHIEHELLGFFRSSYMLNGE-RRFLAVTQFSPTHARKAF 246

  Fly   259 PCFDEPALKAEFTITLVHPSGEDYHALSNMNVDSSVS-QGAFQEVTFAKSVPMSTYLACFIVSDF 322
            ||||||..||.|.::|.|.|  .|.:||||.|:::.| :..:....|:::..||||...:.|.:|
Zfish   247 PCFDEPIYKATFRVSLKHES--SYQSLSNMPVEATTSDEDGWVTNHFSRTPRMSTYYLAWAVCNF 309

  Fly   323 AYKQVSIDTKGIGETFSMSVYATPE--QLDKVDLAVTIGKGVIEYYIDYFQIAYPLPKLDMAAIP 385
            .||:...| .|:    .:.:||.|:  |....|.|:.|.|.::::|.|||::.|.|||||:.|:|
Zfish   310 TYKEAVAD-NGV----LIRLYARPDAIQSGSGDYALRITKRLLQFYQDYFKVKYSLPKLDLLAVP 369

  Fly   386 DFVSGAMEHWGLVTYRETSLLYDEATSSATNKQRIASVIAHEFAHMWFGNLVTMNWWNDLWLNEG 450
            .....|||:|||..:.|..:|.|...||.:.:..:..|:.||..|.|||:|||..||.|:||.||
Zfish   370 KHPYSAMENWGLSVFVEQKILLDPEVSSFSYQMELTVVVVHEICHQWFGDLVTPVWWEDVWLKEG 434

  Fly   451 FASFVEYLGVDAVYPEWKMRDQ-FTVSTLHSVLTLDGTLGSHPIIQTVENPDQITEIFDTITYSK 514
            ||.:.||:|.|.::|:|.|..| |....||.|:.|||...||||.|.|.....|..:||.|.|.|
Zfish   435 FAHYFEYIGADFLFPKWNMEKQRFLTDVLHEVMLLDGLASSHPISQQVFEATDIDRVFDWIAYKK 499

  Fly   515 GSSLVRMLEDFLGETTFRQAVTNYLNEYKYSTAETGNFFTEIDKL----ELGYNVTEIMLTWTVQ 575
            |::|:|||.:.:|:|.|::|:.:||..:.|..|...:.:.::.:.    ....|:|::|..||:|
Zfish   500 GAALIRMLANVMGQTLFQRALNDYLMTHMYGNAARDDLWNKLSEAMQREGKDINITQVMDRWTLQ 564

  Fly   576 MGLPVVTIEKVS--DTEYKLTQKRFLSNPNDYDAD---HEPSEFN--YRWSIPITYFTSSDSVVQ 633
            ||.|||||.|..  |....::|:.|:     ||.|   ..|..||  ::|.||:|....:.|.:.
Zfish   565 MGYPVVTISKNDSLDNSITISQEHFV-----YDTDAKIQNPELFNKSFQWQIPLTLAVGNASHIS 624

  Fly   634 R---LWFYHDQSEITVTVPAAVEWIKFNADQVGYYRVNYDTDLWNDLADQLVVQPSAFGSVDRAH 695
            .   :|..:......|.......|:..|.:|.||:|||||...|..|..||:..|:.....:||.
Zfish   625 TETIIWVTNKSEAHRVGHMVGETWLLGNINQTGYFRVNYDLHNWKLLIQQLMSNPTIISVGNRAG 689

  Fly   696 LLNDAFALADSTQLPYATAFELTRYLDKETDYVPWSVAASRLTSLKRTLYYTSTYAKYKKYATAL 760
            |::|.|.||.:..||.....::..||.:|.:::||..|:..|..|.:.|..|..::.:..|....
Zfish   690 LIDDVFNLARAGYLPQNVPLQMISYLSQEPEFLPWHAASRALYQLDKLLDRTLDHSLFSDYVLRQ 754

  Fly   761 IEPIYTALTWT--------VGEDHLDNRLRVTALSAACSLGLESCLTEAGEQFNAWLAKPEDRPK 817
            :||.|..|.|.        :...:....|:...:..|||.|.:.|..:|....:.|::..::|..
Zfish   755 VEPKYHKLGWPATSPDGSFMHSAYQTEELQREVIMLACSFGNKHCHRQAVSLISDWISSNKNRIP 819

  Fly   818 ADVRETVYYYGIQSVGSQEDWDAVWELFVNESDASEKSKLMYGLSAIQIPWILQRYIDLAWNEEY 882
            .:||:.||..|: |:..::.|:.:|..|.:.:..|||..|:..|:.....::|.|.::|:...:.
Zfish   820 PNVRDIVYCTGV-SLMDEDVWEFIWMKFHSSTAVSEKKVLLEALTCSDNIFLLNRLLNLSLTSDL 883

  Fly   883 VRGQDYFTCLTYISANPVGESLVWDYVRENWQRLVDRFG----LNERYLGNLIPSITARFSTQTK 943
            |..||....:.:::.||:|..|.|.|.||.|..|..|:|    :|.:    ||..:|...:|:.:
Zfish   884 VPDQDVIDVIIHVARNPLGRHLAWRYFREKWDILNSRYGEALFMNSK----LISGVTEFLNTEAE 944

  Fly   944 LEEMEQFFAKYPEAGAGTAARVRALETVKNNIVWLAENLEGVDAWLDKQP 993
            |.|:::|.  ....|....|..||:|.|:.|:.|.....|....||.|.|
Zfish   945 LNELKEFI--LTSGGESAPAFARAVEIVQANVKWHILFQEQFYQWLRKAP 992

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8773	NP_650273.2	KLF9_13_N-like	<17..118	CDD:425361	15/100 (15%)
		M1_APN-Q_like	130..573	CDD:341064	161/452 (36%)
		ERAP1_C	654..973	CDD:463368	95/330 (29%)
trhde.1	XP_001345457.3	M1_APN-Q_like	118..563	CDD:341064	162/452 (36%)
		ERAP1_C	648..975	CDD:463368	96/333 (29%)