Protein Alignment wntD and WNT10B

DIOPT Version :10

• Sequence 1: NP_650272.1
• Gene: wntD / 41633
• FlyBaseID: FBgn0038134
• Length: 309
• Species: Drosophila melanogaster
• Sequence 2: NP_003385.2
• Gene: WNT10B / 7480
• HGNCID: 12775
• Length: 389
• Species: Homo sapiens
• Alignment Length: 335
• Identity: 81/335 - (24%)
• Similarity: 123/335 - (36%)
• Gaps: 95/335 - (28%)

  Fly    38 DITG---KGLKQALDSCQQSFQWQRWNC---------PSQDFVQKNSKPEENSPNREDVYVAAIS 90
            |:|.   :||..|:..||...:.|||||         |....:.|..       .||..:..::.
Human    67 DVTASALQGLHIAVHECQHQLRDQRWNCSALEGGGRLPHHSAILKRG-------FRESAFSFSML 124

  Fly    91 MAAIVHTLTKDCANGVIAGCGC--------------------------TENALNVP--------- 120
            .|.::|.:...|:.|.:..|||                          ..::|..|
Human   125 AAGVMHAVATACSLGKLVSCGCGWKGSGEQDRLRAKLLQLQALSRGKSFPHSLPSPGPGSSPSPG 189

  Fly   121 ---------CAHEPTKALEQYEKHFGSGSGAIG--------HNRRVVGALLQRSLEQECRCKQPG 168
                     |.|:.... |::.:.|.....|..        ||.||...::..:|:::|:|.
Human   190 PQDTWEWGGCNHDMDFG-EKFSRDFLDSREAPRDIQARMRIHNNRVGRQVVTENLKRKCKCH--- 250

  Fly   169 AVQGECQEEECVAVLKPFEAIAQDLLQMYDDAIQLEGASSNLKIMWQNIP----LDSLVFMQDSP 229
            ...|.||.:.|......|.|:...|.:....||.::..:.|.......:.    ...||:.:.||
Human   251 GTSGSCQFKTCWRAAPEFRAVGAALRERLGRAIFIDTHNRNSGAFQPRLRPRRLSGELVYFEKSP 315

  Fly   230 NYCERDATGLWKGTRGRQCSK-----DGSGSLEERLSCQQLCRVCGYRVRSQHVRTERRCNCKLV 289
            ::||||.|....|||||.|:|     ||.||         ||...|:.|..| .|.| ||:|:..
Human   316 DFCERDPTMGSPGTRGRACNKTSRLLDGCGS---------LCCGRGHNVLRQ-TRVE-RCHCRFH 369

  Fly   290 WGFRLQCDVC 299
            |...:.||.|
Human   370 WCCYVLCDEC 379

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wntD	NP_650272.1	Wnt_Wnt8	28..309	CDD:381714	81/335 (24%)
WNT10B	NP_003385.2	Wnt_Wnt10b	45..389	CDD:381730	81/335 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	171..197		2/25 (8%)