Protein Alignment wntD and WNT7A

DIOPT Version :9

• Sequence 1: NP_650272.1
• Gene: wntD / 41633
• FlyBaseID: FBgn0038134
• Length: 309
• Species: Drosophila melanogaster
• Sequence 2: NP_004616.2
• Gene: WNT7A / 7476
• HGNCID: 12786
• Length: 349
• Species: Homo sapiens
• Alignment Length: 310
• Identity: 84/310 - (27%)
• Similarity: 128/310 - (41%)
• Gaps: 62/310 - (20%)

  Fly    39 ITGKGLKQALDSCQQSFQWQRWNCPSQDFVQKNSKPEENSPNREDVYVAAISMAAIVHTLTKDCA 103
            :.|:|.:..||.||..|:..||||.:........| |....:||..:..||..|.:.|.:|..|.
Human    61 VIGEGSQMGLDECQFQFRNGRWNCSALGERTVFGK-ELKVGSREAAFTYAIIAAGVAHAITAACT 124

  Fly   104 NGVIAGCGCTENALNVPCAHEPTKALEQYEKHFG---SGSGA-----IG---------------- 144
            .|.::.|||.:....            ||.:..|   .|..|     ||
Human   125 QGNLSDCGCDKEKQG------------QYHRDEGWKWGGCSADIRYGIGFAKVFVDAREIKQNAR 177

  Fly   145 -----HNRRVVGALLQRSLEQECRCKQPGAVQGECQEEECVAVLKPFEAIAQDLLQMYDDAIQLE 204
                 ||......:|:.:::.||:|.   .|.|.|..:.|...|..|..:...|...|::|:.:|
Human   178 TLMNLHNNEAGRKILEENMKLECKCH---GVSGSCTTKTCWTTLPQFRELGYVLKDKYNEAVHVE 239

  Fly   205 --GASSNLKIMWQNI--------PLDS-LVFMQDSPNYCERDATGLWKGTRGRQCSKDGSGSLEE 258
              .||.|.:..:..|        |:|: ||:::.||||||.|......||:||.|:|    :..:
Human   240 PVRASRNKRPTFLKIKKPLSYRKPMDTDLVYIEKSPNYCEEDPVTGSVGTQGRACNK----TAPQ 300

  Fly   259 RLSCQQLCRVCGYRVRSQHVRTERRCNCKLVWGFRLQCDVCVQLERQYSC 308
            ...|..:|...||... |:.|. .:||||..|...::|:.|.:....|:|
Human   301 ASGCDLMCCGRGYNTH-QYARV-WQCNCKFHWCCYVKCNTCSERTEMYTC 348

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wntD	NP_650272.1	wnt	41..308	CDD:302926	83/306 (27%)
WNT7A	NP_004616.2	Wnt_Wnt7a	32..349	CDD:381723	84/310 (27%)
		Disordered linker. /evidence=ECO:0000269|PubMed:30026314	238..266		6/27 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3913
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810