DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8630 and Scd3

DIOPT Version :9

Sequence 1:	NP_731781.1	Gene:	CG8630 / 41629	FlyBaseID:	FBgn0038130	Length:	408	Species:	Drosophila melanogaster
Sequence 2:	NP_077770.1	Gene:	Scd3 / 30049	MGIID:	1353437	Length:	359	Species:	Mus musculus

Alignment Length:	355	Identity:	165/355 - (46%)
Similarity:	226/355 - (63%)	Gaps:	14/355 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSPNIIGSTFILAETAIADGNNNKMAATPAASAAPSAATPSQKVAKKAEAKTP-----ENKPYEL 60
            |:|:...:|.|.|..:.:..|..:...|     .|.......:...|.:...|     |..|.:|
Mouse    10 MTPSYTTTTTITAPPSGSLQNGREKVKT-----VPLYLEEDIRPEMKEDIYDPTYQDEEGPPPKL 69

  Fly    61 EIVWRNVGLFVILHSMALYGLYLVFAESAYWELLP-VYATMFLGGLGITAGVHRLWSHKAYKAKL 124
            |.||||:.|..:||..||||:.||.:...|..|.. ||..:.:.|:|  |||||||||:.|||:|
Mouse    70 EYVWRNIILMALLHVGALYGITLVPSCKLYTCLFAFVYYVISIEGIG--AGVHRLWSHRTYKARL 132

  Fly   125 PLRIFLMLCQSLAFQNSIWEWTRDHRVHHKFTDTHADPHNSRRGFFFAHMGWLMCKKHPDVTSKG 189
            ||||||::..::||||.::||.||||.||||::||||||||||||||:|:|||:.:|||.|..||
Mouse   133 PLRIFLIIANTMAFQNDVYEWARDHRAHHKFSETHADPHNSRRGFFFSHVGWLLVRKHPAVKEKG 197

  Fly   190 KQISMEDIEQDPVVMFQKKMYFVVMPICCFALPMIFPYYVMGSSLRVCFFTCSMLRFCLSLHFTW 254
            .::.|.|::.:.:||||::.|...:.:.||.||.:.|:|..|.:....|:..::||:.:.|:.||
Mouse   198 GKLDMSDLKAEKLVMFQRRYYKPGILLMCFILPTLVPWYCWGETFLNSFYVATLLRYAVVLNATW 262

  Fly   255 LVNSAAHFYGMKPYDVNVSAMNNKLVSTLTIGEGWHNYHHVFPWDYKAAELGTYSFNWTTAFIDV 319
            |||||||.||.:|||.|:....|.|||..::|||:|||||.||:||.|:|. .:..|:||.|||.
Mouse   263 LVNSAAHLYGYRPYDKNIDPRQNALVSLGSMGEGFHNYHHAFPYDYSASEY-RWHINFTTFFIDC 326

  Fly   320 MAKIGQAYDLKFVSQEMVYKRVLRTGDGSH 349
            ||.:|.|||.|.||:..|..|:.|||||||
Mouse   327 MAALGLAYDRKRVSKATVLARIKRTGDGSH 356

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8630	NP_731781.1	Delta9-FADS-like	90..330	CDD:239582	126/240 (53%)
CG8630	NP_731781.1	FA_desaturase	91..297	CDD:278890	107/206 (52%)
Scd3	NP_077770.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..34		6/23 (26%)
		Delta9-FADS-like	97..337	CDD:239582	126/242 (52%)
		FA_desaturase	102..306	CDD:278890	108/205 (53%)
		Histidine box-1. /evidence=ECO:0000305	120..125		4/4 (100%)
		Histidine box-2. /evidence=ECO:0000305	157..161		2/3 (67%)
		Histidine box-3. /evidence=ECO:0000305	298..302		3/3 (100%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845370
Domainoid	1	1.000	56	1.000	Domainoid score	I10942
eggNOG	1	0.900	-	-		E1_COG1398
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG63267
OrthoDB	1	1.010	-	-		D296120at33208
OrthoFinder	1	1.000	-	-		FOG0000495
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100468
Panther	1	1.100	-	-	O	PTHR11351
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X207
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.720