DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8630 and SPCC1281.06c

DIOPT Version :9

Sequence 1:	NP_731781.1	Gene:	CG8630 / 41629	FlyBaseID:	FBgn0038130	Length:	408	Species:	Drosophila melanogaster
Sequence 2:	NP_588170.1	Gene:	SPCC1281.06c / 2538753	PomBaseID:	SPCC1281.06c	Length:	479	Species:	Schizosaccharomyces pombe

Alignment Length:	370	Identity:	126/370 - (34%)
Similarity:	189/370 - (51%)	Gaps:	46/370 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 PAASAAPSAAT---------------------PSQKVAKKAEAKTPENKPYELEIVWRNVGLFVI 72
            |:|:|..||.|                     |.:|...|| .|..:.:|:.::..||::..
pombe     4 PSATAFSSATTQPTTEGNASMRKRTIPVVPSVPERKWDPKA-PKHIQEQPWTMQNWWRHLNW--- 64

  Fly    73 LHSMALYGL-----YLVFAESAYWELLPVYATMF--LGGLGITAGVHRLWSHKAYKAKLPLRIFL 130
            ||.|.::||     |.||......:.| ::|.::  ..|||||||.||||||:|||||.||..||
pombe    65 LHCMLIFGLPMIAIYGVFTTPLQTKTL-IFAIIYYAYSGLGITAGYHRLWSHRAYKAKKPLEYFL 128

  Fly   131 MLCQSLAFQNSIWEWTRDHRVHHKFTDTHADPHNSRRGFFFAHMGWLMCKKHPDVTSKGKQISME 195
            ....:.||:.||..|:||||.||::|||..||:|.::||::||:||::..::|....:.   .:.
pombe   129 AAGGAAAFEGSIRWWSRDHRAHHRYTDTDKDPYNVKKGFWYAHVGWMIILQNPRRIGRS---DVS 190

  Fly   196 DIEQDPVVMFQKKMYFVVMPICCFALPMIFPYYVMGSSLRVCFFTCSMLRFCLSLHFTWLVNSAA 260
            |:..||.|||..:.:..:.....|..|.:|...:.| ..|..:|...:.|.....|.|:.|||.|
pombe   191 DLNSDPFVMFNHRHFLPIASFMAFIFPSLFCGLLWG-DYRGGYFYAGVCRLVFVHHATFCVNSLA 254

  Fly   261 HFYGMKPYDVNVSAMNNKLVSTLTIGEGWHNYHHVFPWDYKAAELGTYSFNWTTAFIDVMAKIGQ 325
            |..|.:|:|...||.|:.:.:.:|:|||.|||||.||.||:.. |..|.::.|..||.:.:..|.
pombe   255 HLIGSQPFDDTNSARNHFITALVTLGEGNHNYHHAFPNDYRNG-LRWYEYDPTKIFIYIASLFGL 318

  Fly   326 AYDLKFVSQEMVYKRVLRTGDGSHIAALLD---ANNNSAIPTSEL 367
            ||:|.......:.|.:::...     .:||   |..|..||..:|
pombe   319 AYNLNTFPDNEIQKGIVQQKQ-----KVLDRWRAKLNWGIPLEQL 358

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8630	NP_731781.1	Delta9-FADS-like	90..330	CDD:239582	95/241 (39%)
CG8630	NP_731781.1	FA_desaturase	91..297	CDD:278890	83/207 (40%)
SPCC1281.06c	NP_588170.1	OLE1	43..334	CDD:224316	111/300 (37%)
		FA_desaturase	91..304	CDD:278890	89/218 (41%)
		CYB5	345..474	CDD:227599	5/14 (36%)
		Cyt-b5	360..432	CDD:278597
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	180	1.000	Domainoid score	I809
eggNOG	1	0.900	-	-		E1_COG1398
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H136612
Inparanoid	1	1.050	207	1.000	Inparanoid score	I967
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000495
OrthoInspector	1	1.000	-	-		otm47019
orthoMCL	1	0.900	-	-		OOG6_100468
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X207
TreeFam	1	0.960	-	-
	11	10.720