DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8630 and fat-7

DIOPT Version :9

Sequence 1:	NP_731781.1	Gene:	CG8630 / 41629	FlyBaseID:	FBgn0038130	Length:	408	Species:	Drosophila melanogaster
Sequence 2:	NP_504814.1	Gene:	fat-7 / 179100	WormBaseID:	WBGene00001399	Length:	338	Species:	Caenorhabditis elegans

Alignment Length:	315	Identity:	151/315 - (47%)
Similarity:	199/315 - (63%)	Gaps:	17/315 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 PSAATPSQKVAKKAEAKTPENKPYELEIVWRNVGLFVILHSMALYGLY-LVFAESAYWELLPV-Y 97
            |:.....|:.:||.        ||::|||||||.||..||..|..||| |||  .|.|:.... :
Worm    27 PNEVLQVQEESKKI--------PYKMEIVWRNVALFAALHVAAAIGLYELVF--HAKWQTAVFSF 81

  Fly    98 ATMFLGGLGITAGVHRLWSHKAYKAKLPLRIFLMLCQSLAFQNSIWEWTRDHRVHHKFTDTHADP 162
            |.....|.|||||.|||||||:|||..|:||||||..::|.||.|.||.||||.|||:|||.|||
Worm    82 ALYVFSGFGITAGAHRLWSHKSYKATTPMRIFLMLLNNIALQNDIIEWARDHRCHHKWTDTDADP 146

  Fly   163 HNSRRGFFFAHMGWLMCKKHPDVTSKGKQISMEDIEQDPVVMFQKKMYFVVMPICCFALPMIFPY 227
            ||:.|||||.|||||:.:|||.|...|.::.:.|:..|||::||:|.||.::.:.||.||.|.|.
Worm   147 HNTTRGFFFTHMGWLLVRKHPQVKEHGGKLDLSDLFSDPVLVFQRKHYFPLVILFCFILPTIIPV 211

  Fly   228 YVMGSSLRVCFFTCSMLRFCLSLHFTWLVNSAAHFYGMKPYDVNVSAMNNKLVSTLTIGEGWHNY 292
            |....:..:.|:.....|:|.:||.||.:|||||::|.||||.:|||:.|...:.:.:|||.||:
Worm   212 YFWKETAFIAFYVAGTFRYCFTLHATWCINSAAHYFGWKPYDTSVSAVENVFTTVVAVGEGGHNF 276

  Fly   293 HHVFPWDYKAAELGTYS--FNWTTAFIDVMAKIGQAYDLKFVSQEMVYKRVLRTG 345
            ||.||.||:|:|   ||  :|||...||..|.:|..||.|.::.|.:.::|...|
Worm   277 HHTFPQDYRASE---YSLIYNWTRVLIDTAAVLGLVYDRKTIADEFISRQVANHG 328

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8630	NP_731781.1	Delta9-FADS-like	90..330	CDD:239582	122/242 (50%)
CG8630	NP_731781.1	FA_desaturase	91..297	CDD:278890	105/206 (51%)
fat-7	NP_504814.1	Delta9-FADS-like	73..313	CDD:239582	122/242 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160163580
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1398
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H136612
Inparanoid	1	1.050	342	1.000	Inparanoid score	I1385
Isobase	1	0.950	-	0.837287	Normalized mean entropy	S1208
OMA	1	1.010	-	-		QHG63267
OrthoDB	1	1.010	-	-		D296120at33208
OrthoFinder	1	1.000	-	-		FOG0000495
OrthoInspector	1	1.000	-	-		mtm4822
orthoMCL	1	0.900	-	-		OOG6_100468
Panther	1	1.100	-	-	O	PTHR11351
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X207
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.720