Protein Alignment TBC1D5 and Tbc1d5

DIOPT Version :10

• Sequence 1: NP_731780.1
• Gene: TBC1D5 / 41628
• FlyBaseID: FBgn0038129
• Length: 654
• Species: Drosophila melanogaster
• Sequence 2: XP_008764990.1
• Gene: Tbc1d5 / 501088
• RGDID: 1561626
• Length: 827
• Species: Rattus norvegicus
• Alignment Length: 803
• Identity: 214/803 - (26%)
• Similarity: 331/803 - (41%)
• Gaps: 254/803 - (31%)

  Fly    25 GNGAIRVIPEAGAMNSVERYRQEWQVLLEN---LDADPESLRQSAFAGDLKMSKFRSVHWALLLR 86
            |.||...:...|..:|   |.:||..|..|   |.|    :||....|.|:.|:|||:.|.|.|.
  Rat    39 GRGANSNLDCDGTFSS---YMREWDDLFVNNNYLAA----VRQKGINGQLRSSRFRSICWKLFLC 96

  Fly    87 VLTSEHRSWTSQRLQQRVRYDKFRADYVRNPHQLAVDCN---DDPLSQSTQSVWNQYFSDQDLFA 148
            ||..:...|.|:..:.|..|...:..::.||.::....:   ::||||...|:||::|.|::|.:
  Rat    97 VLPQDKSQWISRIKELRSWYSNIKEIHITNPRKVVGQQDLMINNPLSQDEGSLWNKFFQDKELRS 161

  Fly   149 VIRQDVVRTFPGVDFFRKPLVQNAMVNILFYYAREHPYMCYRQGMHEILAPIIFVVYSDHQSLLH 213
            :|.|||.||||.:.||::..|:..:.::||.||||:..:.|:|||||:||||||.::.|||:.||
  Rat   162 MIEQDVRRTFPEMQFFQQENVRKILTDVLFCYARENEQLLYKQGMHELLAPIIFTLHCDHQAFLH 226

  Fly   214 FSELAKTDINPTLLDVLDPAYLEADTYSLFSRLMASVESYYRVSNLVSTPGGHIEQRAES----- 273
            .||.|:.  :..:..:|:|.|||.|.|::||:||.:.|.::....       |..|:.:.
  Rat   227 ASESAQP--SEEMKTLLNPEYLEHDAYAMFSQLMETAEPWFSTFE-------HDGQKGKETLMPP 282

  Fly   274 -----PGDNETSTEAEVIGQLNFIRDKILAKQDQHLHHYLQKMEIPLHIFGIRWLRLLFGREFML 333
                 |.|  ......::.::|.|:|.:|.|.|..|:.:|.::|||..|:|:||:||||||||.|
  Rat   283 IPFARPQD--LGPTVAIVTKVNQIQDHLLKKHDTELYMHLNRLEIPPQIYGLRWVRLLFGREFPL 345

  Fly   334 LDLLLLWDAIFADSDRFDLPNYILVAMLVHIRDKLLLSDYTTSLTYLMRYPNNVDVHLVLRHALF 398
            .|||::|||:|||.....|.:|:..|||::|||.|:.|:|.|.|..||.||...|:|.::..|||
  Rat   346 QDLLVVWDALFADGLHLSLVDYVFTAMLLYIRDALISSNYQTCLGLLMHYPLIGDIHSLILKALF 410

  Fly   399 MLNPKQ------FEYPPN-----------------------------AFTCVSF----------- 417
            :.:||:      :::.||                             :.:.::|
  Rat   411 LRDPKRNPRPVTYQFHPNLDYYKARGADLMNKSRTNARGAPLNIHKVSNSLINFGRKLIAPASAP 475

  Fly   418 ---------ANSS---------------------------------------------------- 421
                     :|||
  Rat   476 GSMGGPVPGSNSSSSFSAAVPFRTSAEAPRHHSQQQRQQQQQQQQQQQQQQQQQQQRLMKSESMP 540

  Fly   422 -------------ADKDVPPPA-----GQRPRTNSENSSMAT----------------------- 445
                         |...||..|     ||.|:|.|.:.||.:
  Rat   541 VQLNKGDVVTGSDAQVSVPVQALTDLQGQSPKTISSSPSMESLPGGREPPGSPPSSATKRDSFFS 605

  Fly   446 ----------------SGSQIDRQITFMQ-ERNAADSSA--LAKLQDTH-----RVAMDGYLENS 486
                            |..:::.||:|:| :.|..|:..  .||:.|.|     .|.:...||..
  Rat   606 HIARSRSHSKAMGRKESEEELEAQISFLQGQLNDLDAMCKYCAKVMDMHLVNIQDVVLQENLEKE 670

  Fly   487 PELL--RLELKNAQTVIK----IARSKLQS------------YLS------TVRHHVGKQANGSE 527
            .::|  ...||..:.::|    ..:|:|::            |.|      |......|||  |.
  Rat   671 DQILVSLAGLKQIKDILKGSLRFNQSQLEAEENEQITIADDHYCSSGQDQGTQGPRAAKQA--SS 733

  Fly   528 EL-----GRTLDGIEELCSFLDVKFMFPLHQRSAPIDQALEANEQKQL---NTVSKPPKPTAS-- 582
            |:     |.|.|..          .:...........:|.....|..|   ||..|...||.|
  Rat   734 EMPGCTGGATSDDF----------ILVSKEDEGRRAKEAFSGQAQPLLTLRNTSGKSRVPTCSPL 788

  Fly   583 --STPANAPAALSATGGYQMPEN 603
              |.|...||:.|::.....|::
  Rat   789 VFSDPLMGPASASSSNPSSSPDD 811

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBC1D5	NP_731780.1	TBC	<150..369	CDD:214540	94/228 (41%)
Tbc1d5	XP_008764990.1	TBC	79..381	CDD:214540	121/312 (39%)