Protein Alignment TBC1D5 and Tbc1d22b

DIOPT Version :10

• Sequence 1: NP_731780.1
• Gene: TBC1D5 / 41628
• FlyBaseID: FBgn0038129
• Length: 654
• Species: Drosophila melanogaster
• Sequence 2: NP_001401270.1
• Gene: Tbc1d22b / 381085
• MGIID: 2681867
• Length: 514
• Species: Mus musculus
• Alignment Length: 366
• Identity: 89/366 - (24%)
• Similarity: 157/366 - (42%)
• Gaps: 72/366 - (19%)

  Fly    41 VERYRQEWQVLLENLDADPESLRQSAFAGDLKMSKFRSVHWALLLRVL--TSEHRSWTSQRLQQR 103
            :|::||    ||.:.:.|.:.||:.::.|..:  :.|.|.|.||...|  .:|.|..|.||  :|
Mouse   195 LEKFRQ----LLSSHNTDLDELRKWSWPGVPR--EVRPVTWRLLSGYLPANTERRKLTLQR--KR 251

  Fly   104 VRYDKFRADYV--RNPHQLAVDCNDDPLSQSTQSVWNQYFSDQDLFAVIRQDVVRTFPGVDFFRK 166
            ..|..|...|.  ||...                       .||.:..|..|:.||.|.:..|::
Mouse   252 EEYFGFIEQYYDSRNEEH-----------------------HQDTYRQIHIDIPRTNPLIPLFQQ 293

  Fly   167 PLVQNAMVNILFYYAREHPYMCYRQGMHEILAPIIFVVYSDHQSLLHFSELAKTDINPTLLDVLD 231
            ||||.....|||.:|..||...|.||:::::.|...|..|::..    .::...|:.....|:|
Mouse   294 PLVQEIFERILFIWAIRHPASGYVQGINDLVTPFFVVFLSEYVE----EDVENFDVTNLSQDML- 353

  Fly   232 PAYLEADTYSLFSRLMASVESYYRVSNLVSTPGGHIEQRAESPGDNETSTEAEVIGQLNFIRDKI 296
             ..:|||::...|:|:..::..|..:.    ||  |:::.::                   .:::
Mouse   354 -RSIEADSFWCMSKLLDGIQDNYTFAQ----PG--IQKKVKA-------------------LEEL 392

  Fly   297 LAKQDQHLHHYLQKMEIPLHIFGIRWLRLLFGREFMLLDLLLLWDAIFADSDRFD-LPNYILVAM 360
            :::.|:.:|.:.::.|:....|..||:..|..||..|...:.|||...::.:.|. ...|:..|.
Mouse   393 VSRIDEQVHSHFRRYEVEYLQFAFRWMNNLLMRELPLRCTIRLWDTYQSEPEGFSHFHLYVCAAF 457

  Fly   361 LVHIRDKLL-LSDYTTSLTYLMRYP----NNVDVHLVLRHA 396
            |:..|.::| ..|:...|..|...|    .|.::.|:|..|
Mouse   458 LIKWRKEILDEEDFQGLLMLLQNLPTIHWGNEEIGLLLAEA 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBC1D5	NP_731780.1	TBC	<150..369	CDD:214540	52/219 (24%)
Tbc1d22b	NP_001401270.1	TBC	216..466	CDD:214540	72/307 (23%)