Protein Alignment TBC1D5 and Tbc1d1

DIOPT Version :10

• Sequence 1: NP_731780.1
• Gene: TBC1D5 / 41628
• FlyBaseID: FBgn0038129
• Length: 654
• Species: Drosophila melanogaster
• Sequence 2: NP_001414246.1
• Gene: Tbc1d1 / 360937
• RGDID: 1304562
• Length: 1257
• Species: Rattus norvegicus
• Alignment Length: 581
• Identity: 115/581 - (19%)
• Similarity: 201/581 - (34%)
• Gaps: 183/581 - (31%)

  Fly    20 LEHLPGNGAIRVIPEAGAMNSVE--------RYRQEW------QVLLENLDADPESLRQSAFAGD 70
            |..||....:..:.|.|....|:        ..|:.|      |:||..::.:.:.|:.|  ..|
  Rat   777 LGELPPRSPLEPVCEDGPFGPVQEEKKKTSRELRELWKKAILQQILLLRMEKENQKLQAS--END 839

  Fly    71 L--KMSKFRSVHWALLLRVLTSEHRSWTSQRLQQRVRYD---------------------KFRAD 112
            |  |..|.........|:.:|:......|...:.::::|                     ||.|:
  Rat   840 LLNKRLKLDYEEITPCLKEVTTVWEKMLSTPGRSKIKFDMEKVHSAVGQGVPRHHRGEIWKFLAE 904

  Fly   113 --YVRNPHQLAVDCNDDPLSQSTQSVWNQYFSDQDLFAVIRQDVVRTFPGVDFFRKPL--VQNAM 173
              ::::|........|.|..:..:.:.:|..:       |..|:.||||...:|...|  .|.::
  Rat   905 QFHLKHPFPSKQQPKDVPYKELLKKLTSQQHA-------ILIDLGRTFPTHPYFSAQLGAGQLSL 962

  Fly   174 VNILFYYAREHPYMCYRQGMHEILAPIIFVVYSDHQSLLHFSELAKTDINPTLLDVLDPAYLEAD 238
            .|||..|:.....:.|.||: ..:|.|:         |||.|                    |.:
  Rat   963 YNILKAYSLLDQEVGYCQGL-SFVAGIL---------LLHMS--------------------EEE 997

  Fly   239 TYSLFSRLM--ASVESYYRVSNLVSTPGGHIEQRAESPGDNETSTEAEVIGQLNFIR-DKILAKQ 300
            .:.:...||  ..:...||..                          .:|.|:...: .::|...
  Rat   998 AFKMLKFLMFDMGLRKQYRPD--------------------------MIILQIQMYQLSRLLHDY 1036

  Fly   301 DQHLHHYLQKMEIPLHIFGIRWLRLLFGREFMLLDLLLLWDAIFADSDRFDLPNYILVAMLVHIR 365
            .:.|:::|::.||...::...|...:|..:|.|..:..::|.||.....          ::..:.
  Rat  1037 HRDLYNHLEEYEIGPSLYAAPWFLTVFASQFPLGFVARVFDMIFLQGSE----------VIFKVA 1091

  Fly   366 DKLLLSDYTTSLTYLMRYPNNVDVH--LVLRHALFMLNPKQFEYPPNAFTCVSFANSSADKDVPP 428
            ..||.|                  |  |:|:|             .|..|.|.|.     |:..|
  Rat  1092 LSLLGS------------------HKPLILQH-------------ENLETIVDFI-----KNTLP 1120

  Fly   429 PAG--QRPRTNSENSSMATSGSQIDRQITFMQ------ERNAADSSALAKLQDTHRVAMDGYLEN 485
            ..|  |..:|.|:...|     .|.:|:...:      :....|||.|:   |..|  || .||.
  Rat  1121 NLGLVQMEKTISQVFEM-----DIAKQLQAYEVEYHVLQEELIDSSPLS---DNQR--MD-KLEK 1174

  Fly   486 SPELLRLELKNAQTVIKIARSKLQSYLSTVRHHVG-----KQANGSEELGRT--LDGIEEL 539
            :...||.:..:....:::|.:::||...||...:.     |||..:.|:.|:  |..:|||
  Rat  1175 TNSSLRKQNLDLLEQLQVANARIQSLEVTVEKLLTSESKLKQAVLTLEMERSALLQMVEEL 1235

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBC1D5	NP_731780.1	TBC	<150..369	CDD:214540	41/223 (18%)
Tbc1d1	NP_001414246.1	None