Protein Alignment TBC1D5 and Tbc1d15-17

DIOPT Version :10

• Sequence 1: NP_731780.1
• Gene: TBC1D5 / 41628
• FlyBaseID: FBgn0038129
• Length: 654
• Species: Drosophila melanogaster
• Sequence 2: NP_608503.1
• Gene: Tbc1d15-17 / 33184
• FlyBaseID: FBgn0031233
• Length: 715
• Species: Drosophila melanogaster
• Alignment Length: 510
• Identity: 102/510 - (20%)
• Similarity: 182/510 - (35%)
• Gaps: 127/510 - (24%)

  Fly     8 AITLNGSSARESLEHLPGNGAIRVI---PEAGAMNSVERYRQE---------WQVLLENLD---A 57
            |.:.||.|...|.|..|.:..:..:   .|....|..:|.|.|         | :..:..|   :
  Fly   296 ACSSNGQSRGGSAEKSPADSELETLNAQDEKIVNNLPDRQRVERGHPLTETQW-LEFQTPDGRIS 359

  Fly    58 DPESLRQSAFAGDLKMSKFRSVHWALLLR--VLTSEHRSWTSQRLQQRVRYDKFRADYVRNPHQL 120
            |...:::..|.|.:..| .|...|..||.  :.:..|.....:|.|:.:.|...:|.:
  Fly   360 DSARIKELIFRGGVVQS-LRPEVWKFLLNYYLWSDTHVERIERRKQKSIEYYNMKAQW------- 416

  Fly   121 AVDCNDDPLSQSTQSVWNQYFSDQDLFAVIRQDVVRT------FPGVDFFRKPLVQNAMVNILFY 179
                    |:.:|....| :...::....|.:||.||      |.|.|.....|:|    .||..
  Fly   417 --------LAMTTTQEAN-FCGYRERKCQIEKDVKRTDRSLQFFAGEDNPNLTLLQ----GILMT 468

  Fly   180 YAREHPYMCYRQGMHEILAPIIFVVYSDHQSLLHFSELAKTDINPTLLDVLDPAYLEADTYSLFS 244
            |...:..:.|.|||.::||||:                 :..:|            |.||:..|.
  Fly   469 YVMYNFDLGYVQGMSDLLAPIL-----------------EIQVN------------EVDTFWCFV 504

  Fly   245 RLMASVESYYRVSNLVSTPGGHIEQRAESPGDNETSTEAEVIGQLNFIRDKILAKQDQHLHHYLQ 309
            ..|..|.:.:.:.                        :|.:..|...|| :::...:..|.:|::
  Fly   505 GFMELVFTNFDID------------------------QAGMKTQFAQIR-RLIEFANAPLFNYMR 544

  Fly   310 KMEIPLHIFGIRWLRLLFGREFMLLDLLLLWDAIFADSDRFDLPNY-ILVAMLVHIRDKLLLSDY 373
            ..:.....|..|||.:.:.||....|:|.||:.::.   |...||: :|.::.:..::..::.|.
  Fly   545 SHDSDNMYFCFRWLLVWYKRELNSEDVLKLWECLWT---RLPCPNFHLLFSVAILDQETRVIIDS 606

  Fly   374 TTSLTYLMRYPN----NVDVHLVLRHAL-FMLNPKQFEYPPNAFTCVSFANSSADKDVPPPAGQR 433
            ....|.::::.|    |:||...|:.|. ..|..|..|..||....:     ..:..:|..||:.
  Fly   607 QYEFTEILKHVNELSGNIDVQKTLQVAEGIYLQLKGSETLPNDIRSI-----IGEPLLPAAAGEE 666

  Fly   434 PRTNSENSSMATSGSQIDRQITFMQERNAADSSALAKLQDTHRVAMDGYLENSPE 488
                       ..|..:|.:.|:..:   .....:.:|....:|.....||.:.|
  Fly   667 -----------IDGGMVDEEPTYSDD---GFDELVKELTPEEKVRQQALLEEACE 707

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBC1D5	NP_731780.1	TBC	<150..369	CDD:214540	48/225 (21%)
Tbc1d15-17	NP_608503.1	TBC	369..598	CDD:214540	63/306 (21%)