Protein Alignment TBC1D5 and Rabgap1l

DIOPT Version :10

• Sequence 1: NP_731780.1
• Gene: TBC1D5 / 41628
• FlyBaseID: FBgn0038129
• Length: 654
• Species: Drosophila melanogaster
• Sequence 2: XP_063128419.1
• Gene: Rabgap1l / 304914
• RGDID: 1304620
• Length: 1066
• Species: Rattus norvegicus
• Alignment Length: 618
• Identity: 120/618 - (19%)
• Similarity: 222/618 - (35%)
• Gaps: 177/618 - (28%)

  Fly    42 ERYRQEWQVLL----ENLDADPESLRQSAFAGDLKMSKFRSVHWALLLRVLTSEHRSWTSQRLQQ 102
            |:....|..||    .||:|.|:.|.....:|         |..||...|       |
  Rat   522 EKILYSWGELLGRWHNNLNARPKGLPTLVKSG---------VPEALRAEV-------W------- 563

  Fly   103 RVRYDKFRADYVRNPHQLAVDCNDDPLSQSTQSVWNQY----FSDQDLFAVIRQDVVRTFPGVDF 163
                            ||...|:|:      |::.::|    ..|....:||.:|:.||||..|:
  Rat   564 ----------------QLLAGCHDN------QAMLDKYRILITKDSAQESVITRDIHRTFPAHDY 606

  Fly   164 FRKP--LVQNAMVNILFYYAREHPYMCYRQGMHEILAPIIFVVYSDHQSLLHFSELAKTDINPTL 226
            |:..  ..|.::..|...|:.....:.|.|| ...||.::         |||..|
  Rat   607 FKDTGGDGQESLYKICKAYSVYDEDIGYCQG-QSFLAAVL---------LLHMPE---------- 651

  Fly   227 LDVLDPAYLEADTYSLFSRLMASVESYYRVSNLVSTPGGHIEQRAESPGDNETSTEAEVIGQLNF 291
                :.|:.          ::.::...|::.:|..              :|......:.. ||
  Rat   652 ----EQAFC----------VLVNIMYKYKLRDLYK--------------NNFEDLHCKFY-QL-- 685

  Fly   292 IRDKILAKQDQHLHHYLQKMEIPLHIFGIRWLRLLFGREFML------LDLLLLWDAIFADSDRF 350
              :|::.:|...|:.:...:.:..|::..:|...||..:|.|      :||||        .:..
  Rat   686 --EKLMQEQLPDLYSHFCDLNLEAHMYASQWFLTLFTAKFPLCMVFHIIDLLL--------CEGL 740

  Fly   351 DLPNYILVAMLVHIRDKLLLSDYTTSLTYLMRYPNNVDVHLVLRHALFMLNPKQFEYPPNAFTCV 415
            ::..::.:|:|...::.||.:|:..:|.:..       |.|          ||::....||...:
  Rat   741 NIIFHVALALLKTSKEDLLQADFEGALKFFR-------VQL----------PKRYRAEENARRLM 788

  Fly   416 SFANSSADKDVPPPAGQRPRTNSENSSMATSGSQIDRQITFMQERNAADSSALAKLQD------- 473
            ..|     .::..|..:..:...|..:|..:..|.:..:...:..|.....|..:|:.
  Rat   789 EQA-----CNIKVPTKKLKKYEKEYQAMRENQLQQEDPMDRYKRENRRLQEASMRLEQENDDLAH 848

  Fly   474 ---THRVAMDGYL---ENSPELLRLEL---KNAQTVIKIARSKLQSYLSTVRHHVGKQANGSE-E 528
               |.::|:...|   |:..::|..||   |......:..:.|.:...:.::....||...:| |
  Rat   849 ELVTSKIALRNDLDQAEDKADVLSKELLFTKQRLVETEEEKRKQEEETAQLKEVFRKQLEKAEYE 913

  Fly   529 LGRTLDGIEE---LCSFLDVKFMFPLHQRSAPIDQALEANEQKQLNTVSKPPKPTASSTPANAPA 590
            :.:|...|.|   :||.|..:    |.::.|...:.|||.:.|.:  ..|......|...|..|.
  Rat   914 IKKTTAIIAEYKQICSQLSTR----LEKQQAASKEELEAVKGKMM--ACKHCSDIFSKEGAGKPV 972

  Fly   591 ALSATG-GYQMPENAFMHSSMRRLLGELREIEL 622
            |:|... |.:..:.   ..|:::   :|||:||
  Rat   973 AISREDQGLEADDE---KDSLKK---QLREMEL 999

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBC1D5	NP_731780.1	TBC	<150..369	CDD:214540	41/226 (18%)
Rabgap1l	XP_063128419.1	None