Protein Alignment TBC1D5 and Tbc1d14

DIOPT Version :10

• Sequence 1: NP_731780.1
• Gene: TBC1D5 / 41628
• FlyBaseID: FBgn0038129
• Length: 654
• Species: Drosophila melanogaster
• Sequence 2: NP_001106833.1
• Gene: Tbc1d14 / 100855
• MGIID: 1098708
• Length: 714
• Species: Mus musculus
• Alignment Length: 400
• Identity: 82/400 - (20%)
• Similarity: 146/400 - (36%)
• Gaps: 98/400 - (24%)

  Fly    20 LEHLPGNGAIRVIPEAGAMNSVERYRQEWQVLLENLDADPESL-----RQSAFAGDLKMSKFRSV 79
            ||..|.|...:...||      :::||:::.::  |.|....|     |:.......|:.:  |:
Mouse   337 LEDRPANLPAKPAEEA------QKHRQQYEEMV--LQAKKRELKEAQRRRKQLEERCKVEE--SI 391

  Fly    80 HWALLL---RVLTSEHRSWTSQRLQQ--------RVR---YDKFRADYVRNPHQLAVDC------ 124
            ..|:|.   .:|.:....|.|::::.        .||   :.....:.:...|:|...|
Mouse   392 GNAVLTWNNEILPNWETMWCSKKVRDLWWQGIPPSVRGKVWSLAIGNELNITHELFDICLARAKE 456

  Fly   125 NDDPLSQSTQSVWNQ--YFSDQDLFA---VIRQDVVRTFPGVDFFRKPLVQNAMV-NILFYYARE 183
            ....||.....|.|:  .||..|..|   :|:.|:.||||.:..|::....:.|: :||..|...
Mouse   457 RWRSLSTGGSEVENEDAGFSAADREASLELIKLDISRTFPNLCIFQQGGPYHDMLHSILGAYTCY 521

  Fly   184 HPYMCYRQGMHEILAPIIFVVYSDHQSLLHFSELAKTDINPTLLDVLDPAYLEADTYSLFSRLMA 248
            .|.:.|.||| ..:|.::.:......:.:.||.|..   .|..:     |:...| :.|.....|
Mouse   522 RPDVGYVQGM-SFIAAVLILNLDTADAFIAFSNLLN---KPCQM-----AFFRVD-HGLMLTYFA 576

  Fly   249 SVESYYRVSNLVSTPGGHIEQRAESPGDNETSTEAEVIGQLNFIRDKILAKQDQHLHHYLQKMEI 313
            :.|.::. .||                                  .|:.|        :.:|..:
Mouse   577 AFEVFFE-ENL----------------------------------PKLFA--------HFKKNNL 598

  Fly   314 PLHIFGIRWLRLLFGREFMLLDLLL-LWDAIFADSDRFDLPNYILVAMLVHIRDKLLLSDYTTSL 377
            ...|:.|.|:..|:.:. :.|||.. :||....|.:.|.....:.:..|  ..|.|...|:..|.
Mouse   599 TADIYLIDWIFTLYSKS-LPLDLACRIWDVFCRDGEEFLFRTALGILKL--FEDILTRMDFIHSA 660

  Fly   378 TYLMRYPNNV 387
            .:|.|.|.::
Mouse   661 QFLTRLPEDL 670

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBC1D5	NP_731780.1	TBC	<150..369	CDD:214540	44/220 (20%)
Tbc1d14	NP_001106833.1	ARGLU	<350..>389	CDD:405931	9/46 (20%)
		TBC	419..651	CDD:214540	57/287 (20%)