Protein Alignment TBC1D5 and tbc1d5

DIOPT Version :10

• Sequence 1: NP_731780.1
• Gene: TBC1D5 / 41628
• FlyBaseID: FBgn0038129
• Length: 654
• Species: Drosophila melanogaster
• Sequence 2: XP_031759404.1
• Gene: tbc1d5 / 100380174
• XenbaseID: XB-GENE-1010688
• Length: 810
• Species: Xenopus tropicalis
• Alignment Length: 711
• Identity: 212/711 - (29%)
• Similarity: 333/711 - (46%)
• Gaps: 140/711 - (19%)

  Fly    44 YRQEWQVLLENLDADPESLRQSAFAGDLKMSKFRSVHWALLLRVLTSEHRSWTSQRLQQRVRYDK 108
            |.:||:.|..| :....::|.....|.|:.|:||||.|.|.|.||..:...|.|:..:.|..|.|
 Frog    53 YSKEWEELFVN-NNYLATIRLKGINGQLRSSRFRSVCWKLFLNVLPQDRSQWISKTEELRTLYKK 116

  Fly   109 FRADYVRNPHQLAVDCN---DDPLSQSTQSVWNQYFSDQDLFAVIRQDVVRTFPGVDFFRKPLVQ 170
            .:..::.||.:.|...:   ::||||...|:||::|.|::|.|:|.|||.||||.:.||::..|:
 Frog   117 IKEIHITNPRKAAGQQDLIINNPLSQDEGSLWNKFFQDKELRAMIEQDVKRTFPEMQFFQQEYVR 181

  Fly   171 NAMVNILFYYAREHPYMCYRQGMHEILAPIIFVVYSDHQSLLHFSELAKTDINPTLLDVLDPAYL 235
            |.:.:|||.||||:.::.|:|||||:||||:|:::.|||:..|.||.||.  :..:.::|:|.||
 Frog   182 NLLTDILFCYARENEHLLYKQGMHELLAPIVFILHCDHQAFSHASEAAKP--SEDMKELLNPEYL 244

  Fly   236 EADTYSLFSRLMASVESYYRVSNLVSTPGGHIEQRAESPGDNETSTEAE---------VIGQLNF 291
            |.|.::|||.||.|.|.::....       | :.|.|......|...|.         ::.::|:
 Frog   245 EHDAFALFSHLMRSAEPWFSTFE-------H-DSRKEKEAILSTMPFARPQDIGPSIAIVSKVNY 301

  Fly   292 IRDKILAKQDQHLHHYLQKMEIPLHIFGIRWLRLLFGREFMLLDLLLLWDAIFADSDRFDLPNYI 356
            |:|::|.|.|..|:.:|.::||...|:|:||:||||||||.|.|||::|||:||||...||.:||
 Frog   302 IQDQLLKKHDIELYMHLNRLEIAPQIYGLRWVRLLFGREFPLQDLLVVWDALFADSITLDLVDYI 366

  Fly   357 LVAMLVHIRDKLLLSDYTTSLTYLMRYPNNVDVHLVLRHALFMLNPKQFEYPPN----------- 410
            .:|||::|||.|:.|:|.|.|..||.||...|||.::..|||:.:||:...|.|
 Frog   367 FIAMLLYIRDALISSNYQTCLGLLMHYPPIGDVHSLILKALFLRDPKKNPRPVNYQFHQNLDYYK 431

  Fly   411 ------------------------AFTCVSFANSSADKDVPPPAGQRPRTNSENSS-MATSGSQI 450
                                    :.:.::|........||......|..:.:|:: ...|.|..
 Frog   432 ARGLDLLNKSRVNSKPGSSAMVKVSSSLMNFGRKLIGPTVPTGGAMSPMMSPQNNNGSGFSSSNN 496

  Fly   451 DRQIT----------FMQERNAADSSALAKLQDTHRVAMDGYLENSPELLRLELKNAQTVIKIAR 505
            .|.|:          |:.|.|.....::.::|.|.|:.       ..|.:.::|...|:...|:.
 Frog   497 SRSISSGLTKPLPNQFVDESNPHPFPSMQQMQQTQRMM-------KSESMPVQLSKGQSSKNISS 554

  Fly   506 S---------------------KLQSYLSTV---RHH---VGKQANGSEE--------LGRTLDG 535
            |                     |.:|:.|.:   |.|   .||:.|  ||        |...|:.
 Frog   555 SPSIESLPGGRDHTDSPPPSAGKKESFFSNISRSRSHSKSQGKKEN--EEDMEAQISFLQGQLND 617

  Fly   536 IEELCSFLDVKFMFPL--HQRSAPIDQALEANEQKQLN-TVSKPPKPTASST--------PANAP 589
            ::.:|.:. .|.|...  |.:...:::.||..::.|:: .|.|..|.....|        .|...
 Frog   618 LDAMCKYC-AKIMNTHLGHIQDVILEEKLEKEDKIQVSLAVLKQIKDILKGTLRFNQSLLEAEEN 681

  Fly   590 AALSATGGYQMPENAFMHSSMR---------RLLGELREIELSTITSD------EKPGNAV 635
            ..:|.|..:...........||         :.:.|..|...|:.:.|      |..||||
 Frog   682 EEISITDDHYCSTMLRKSEEMRGAQEEPRHQQAIAESSENAASSKSDDYILIPREDNGNAV 742

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBC1D5	NP_731780.1	TBC	<150..369	CDD:214540	99/227 (44%)
tbc1d5	XP_031759404.1	TBC	77..379	CDD:214540	130/311 (42%)