Protein Alignment Su(var)3-7 and Gpdh3

DIOPT Version :9

• Sequence 1: NP_524342.3
• Gene: Su(var)3-7 / 41627
• FlyBaseID: FBgn0003598
• Length: 1250
• Species: Drosophila melanogaster
• Sequence 2: NP_732726.2
• Gene: Gpdh3 / 42624
• FlyBaseID: FBgn0263048
• Length: 1304
• Species: Drosophila melanogaster
• Alignment Length: 1170
• Identity: 219/1170 - (18%)
• Similarity: 373/1170 - (31%)
• Gaps: 392/1170 - (33%)

  Fly    18 PDLKMA------SANSETLASATHELKIMDVEGGALVDPDHIEEVETSMVIVVDDDDGDVAMVVE 76
            |:|:.|      .|.:|.:    .:||:||         |..|         |:|.|      ||
  Fly   371 PELRTALDKILTEAGNENI----KQLKVMD---------DWTE---------VNDYD------VE 407

  Fly    77 EDKHP--MRDDPCIE-DIMDDEHAPLVAELQSALNN-----------------------PDDKQA 115
            |..|.  ...|.|:| :||....:...|:|.:.:.:                       .:|:.|
  Fly   408 ETYHEKVASRDSCLETEIMPSRLSVQAAQLYNDIRDGNVGVAFKMDIDEGNRQVRLLLEKEDEMA 472

  Fly   116 SEDPLL-----------EDQEREPDAMSTKTEPSSDAESSHSYHDPMGLLERIEIHDPGDSQDDD 169
            |:..|.           :|..|......|.|...||..||.|.  |.||..:       ||.|..
  Fly   473 SDAALTVISSRLTAGQEDDNARIGHGHITNTSAESDHMSSKSI--PSGLTTK-------DSPDVL 528

  Fly   170 DEDDESSNGGGVDGGMRRKMPRAQRWLLWMKRWPWILHEDSDGTLAFCLYCN-ISINVN------ 227
            |...||.       .:......:|            |.||::......|..| :...::
  Fly   529 DLSCESE-------PLHSSKQNSQ------------LMEDAETNFTERLKVNQLKEQIDKQEAAN 574

  Fly   228 -----NRSRHIQQHNVSLSHQERECNYLAFKKSEEETRGAISDNEIKHEFGTKSYVAAMKQKRIS 287
                 |..:.|:|...:|..:|:..|.:|..|.||:            .|..||.|.:.:.|...
  Fly   575 FKAQENLIKSIRQTIQALGDKEKMENLIAKSKMEED------------PFQLKSQVESSQLKSQV 627

  Fly   288 ETEAFNNFNWLRWLRWHPWLERSMPTGTIGTCRICSVRMNVEFVYLRKRHETTKGHMEALRNLDS 352
            |.|:....|.::...:.|                 ..:.:.|...:|.:.:.....:::|  :|.
  Fly   628 EGESSELKNQIQEEAYEP-----------------ISQADEEPSQIRSQLDEESAQLKSL--MDE 673

  Fly   353 DKRSRKRKRSKSNSVTNSGGDEAE----REKESEPEVGPEDAQDTPVVMMNGDVDSGDDPGKWCA 413
            :.|..:.:....:|:..|..|::|    ..:|.:|...|.|...                   ..
  Fly   674 ENRQLESEMQDESSLLKSSADKSEFVAYNAEEEQPIEEPTDNHQ-------------------YK 719

  Fly   414 LIPDTNPQQCRCTLCNCTMAITSFLRHCKTRAHCHMLSTPAEKGSSDIRGIWAVFADMHPWLIAD 478
            |..|||..:        .:..|....|.::..|                 |.....|.|.:.:
  Fly   720 LRSDTNKLK--------ELMFTDSREHLESEKH-----------------IEVKLQDEHDFDL-- 757

  Fly   479 PEDPSIGYCSVCRKRFMY--GNSEIKRK------------NHEKS----EKHTLALASAKAGIEV 525
            .|:|:||     :|...|  .|.|::.:            :|..|    |..|....:|:..||
  Fly   758 DEEPAIG-----KKDPTYTKENLELQERLEWQKLKQTDKPHHPYSSADLEDSTTNEGNARLPIE- 816

  Fly   526 GSADGRGGDNMD--EEEAAASDQAQSSQTDD----------SEDNDDDNWSEIQKLGKGFAHKSS 578
              .|.| ..|:|  ::......:|:..:|..          ||...|.|..|:..  :..:|..:
  Fly   817 --HDNR-FQNVDRYQDRELVQVRAELKETSGAESEKEINLISEQRPDQNQDEVNL--RPHSHIKT 876

  Fly   579 SEPRKATVRAGVRFYPWLCYSKDRKTQICKFCRVRFHNEAAKARHELSARHVKLVKQFKMRQAKL 643
            .|       .|...:.||..::...:...||    :.||..:...|..             |.||
  Fly   877 EE-------TGHHEWDWLMNNEKIDSDEQKF----YANERMETLSESD-------------QDKL 917

  Fly   644 HQGTNTQTKHNAQDDEESQEQDEEYGEEEEDAEEDSQSNFDLGTVQARKTAR-----ADNKLFVK 703
             |..|.|.|...|.|.:...........|..:||||...      .|:|...     ..|::...
  Fly   918 -QNLNYQLKEALQHDLDVMSASRGNDSNEVLSEEDSNPE------AAKKITEQPLNPTPNQIPAV 975

  Fly   704 PIPATMKGKVMVWKGRFPWLSYKKNEQRGNYAWCKLCEVSLYLPSSKWASKHQRTSRHIRLRIDR 768
            |:|.||..|....:...|..   :|:.|.             :|.....:|.|....      .:
  Fly   976 PLPVTMPSKQSHIREGSPQF---QNQPRS-------------VPPPSPQTKPQSPKE------QQ 1018

  Fly   769 KRNGGNPLKTSNKNSGEISTVVATASALASAEARQKAAMAELQAKYDWLDPDANDENHCHCRVCD 833
            .|....|::..||:  |...:..:||   ..|..::..:::.:|.   ::|.|.|.:...
  Fly  1019 PRRTNAPVEFGNKD--EAMDLNESAS---DQEVPKRKKISKTEAV---IEPVAKDVSMAE----- 1070

  Fly   834 SRLPIKVFYLRQH--DASRKHVENKERQRANAAAAANAPSVSPTSTVDAERQESGMDKESENDMS 896
               |.:..:.::.  .||....|:|.:|:.:..        .|:|..|:.:..:..:|:.:   .
  Fly  1071 ---PNESLHSKKETSPASLSKQESKRKQKRSLR--------RPSSDSDSTKTTNEFEKQRQ---I 1121

  Fly   897 VRSDGSTAEPLAKRSRRSMEVRRIIRALRDSMGKR--------------QEERSQMDMARDMICS 947
            :.:..:..|.:.|:          |..:|....:|              .|.|..||       :
  Fly  1122 IENQKAQLEKMGKK----------ISVMRQGQDRRVSYKGHNPYSADPDLESRPPMD-------T 1169

  Fly   948 SFDIVTRLRTLERESVAH-NESMAQAPP-SVTVSP-IKPPEP------------------RHVMD 991
            ||:   :.||.:.:.:.| ...:..||| ...::| ::.|.|                  ||
  Fly  1170 SFE---KDRTGDYQGLGHQRRKVVVAPPFHPPINPRVRVPRPPFDGRDHEFHTMTTAPVDRH--- 1228

  Fly   992 LFFDSISPTMK--SLPPDLAAEGKSKIMQLVCSLELRAMQRNATTPTPATVSASSKWPSSTTVTP 1054
                 ::|..|  |||..|.....|    ||.:::::..   |..|..|......|.|.....||
  Fly  1229 -----LAPAAKWSSLPTTLKLNRNS----LVANIQVKHF---AALPCQALPKPILKLPMGVPRTP 1281

  Fly  1055  1054
              Fly  1282  1281

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(var)3-7	NP_524342.3	BESS	991..1021	CDD:281011	8/31 (26%)
Gpdh3	NP_732726.2	glycerol3P_DH	6..342	CDD:274551
		NADB_Rossmann	6..174	CDD:304358
		NAD_Gly3P_dh_C	195..336	CDD:284817
		BCOR	<961..1109	CDD:292436	33/193 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11728
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100