Protein Alignment Ace and Ces1a

DIOPT Version :9

• Sequence 1: NP_001163600.1
• Gene: Ace / 41625
• FlyBaseID: FBgn0000024
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_001177304.1
• Gene: Ces1a / 679817
• RGDID: 1583671
• Length: 563
• Species: Rattus norvegicus
• Alignment Length: 587
• Identity: 158/587 - (26%)
• Similarity: 256/587 - (43%)
• Gaps: 95/587 - (16%)

  Fly    44 VVQTSSGPVRGRSVTVQG--REVHVYTGIPYAKPPVEDLRFRKPVPAEPWHGVLDATRLSATCVQ 106
            ||.|..|.|.|:.::::|  :.|.|:.|:|:||||:..|||..|.|||.|..|.:||.....|.|
  Rat    25 VVDTLQGKVLGKYISLEGFTQPVAVFLGVPFAKPPLGSLRFAPPQPAESWSFVKNATSYPPMCSQ 89

  Fly   107 ERYEYFPGFS---GEEIWNPNTNV----SEDCLYINVWAPAKARLRHGRGANGGEHPNGKQADTD 164
                 ..|..   .|...|...||    ||||||:|:::|                       ||
  Rat    90 -----ITGVGPVLSEVFTNQLENVPLEYSEDCLYLNIYSP-----------------------TD 126

  Fly   165 HLIHNGNPQNTTNGLPILIWIYGGGFMTGSATLDIYNADIMAAVGNVIVASFQYRVGAFGFLHLA 229
                    ..:.:.||:::|::|||.::|.|:  .::...::....|:|...|||:|.:|||
  Rat   127 --------LTSKDRLPVMVWVHGGGLLSGGAS--TFDGLALSTHEKVVVVVIQYRLGIWGFL--- 178

  Fly   230 PEMPSEFAEEAPGNVGLWDQALAIRWLKDNAHAFGGNPEWMTLFGESAGSSSVNAQLMSPVTRGL 294
                |...|.:.||.|.:||..|::|:::|...|||:|..:||||||||..||:..::||:|:.|
  Rat   179 ----STGDEHSRGNWGHFDQVAALQWVQNNIVNFGGDPNSVTLFGESAGGESVSVLVLSPLTKNL 239

  Fly   295 VKRGMMQSGTMNAPWSHMTSEKAVEIGKALINDCNCNASMLKTNPAHVMSCMRSVDAKTISVQQW 359
            ..|.:.:||....|.....:.:......|:...|      ..|..|.::.|:|....:.:.....
  Rat   240 FHRAISESGVALTPCLFRENTRLAAEQVAIATGC------AATTSADIVRCLREKTEEELLATTL 298

  Fly   360 NSYSGIL--------SFPSAPT-IDGAFLPADPMTLMKTADLKDYDILMGNVRDEGTYFLLYDFI 415
            ......|        |:|...| |||..||..|..::...:......::|..:.|..:| :...:
  Rat   299 KMKFFALDLHGDPRESYPFLTTVIDGVLLPKAPEEILSEKNFNTVPYIVGINKQEFGWF-IPTMM 362

  Fly   416 DY------FDKDDATALPRDKYLEIMNNIFGKATQAEREAIIFQYTSWEGNPGYQNQQQIGRAVG 474
            .|      .|:..||:|....|  .:.||..:.|....|    :|......|..:....:. .:|
  Rat   363 GYPLSESKLDQKTATSLLWKSY--PLTNISKELTPVATE----KYLGGSDCPDKKKDLFLD-MMG 420

  Fly   475 DHFFTCPTNEYAQALAERGASVHYYYFTHRTS--TSLWGEWMGVLHGDEIEYFFGQPLNNSLQYR 537
            |..|..|:...|:...:..|:.:.|.|.:..|  :.:..:.:...||||:...:|.|.   |:..
  Rat   421 DVLFAVPSVIVARYHRDARATTYVYEFKYHPSFVSDMRPKTVIADHGDEVYSVWGTPF---LKEG 482

  Fly   538 PVERE--LGKRMLSAVIEFAKTGNPAQDG-EEWPNFSKEDPVYYIFSTDDKIEKLARGPLAARCS 599
            ..|.|  |...|:.....||:.|||..:| ..||.:.:::....|.:|..:.:||....:|
  Rat   483 ASEEEINLSTMMMKFWGNFARNGNPNGEGLPHWPEYDEKESYLQIGTTIQQAQKLKYKEVA---- 543

  Fly   600 FW 601
            ||
  Rat   544 FW 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ace	NP_001163600.1	COesterase	41..601	CDD:278561	156/585 (27%)
Ces1a	NP_001177304.1	COesterase	24..545	CDD:278561	156/585 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810