Protein Alignment Ace and ces2a

DIOPT Version :9

• Sequence 1: NP_001163600.1
• Gene: Ace / 41625
• FlyBaseID: FBgn0000024
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_001070720.1
• Gene: ces2a / 566132
• ZFINID: ZDB-GENE-061013-99
• Length: 555
• Species: Danio rerio
• Alignment Length: 646
• Identity: 173/646 - (26%)
• Similarity: 275/646 - (42%)
• Gaps: 170/646 - (26%)

  Fly    25 LVLVLSLHLSGVCGVIDRLVVQTSSGP--------VRGRSVTVQGRE--VHVYTGIPYAKPPVED 79
            ::|.|.|.|:.|...    .||..|||        |||:.|..:|..  |..|.|||:|:|||..
Zfish     5 VLLCLCLTLAPVWSA----PVQEDSGPVAVLKHGSVRGQYVKAKGSPAVVEQYLGIPFAQPPVGP 65

  Fly    80 LRFRKPVPAEPWHGVLDATRLSATCVQERYEYFPGFSGEEIWNPN---------------TNVSE 129
            .|...|.|.:.|.|:.:||.....|:|               ||:               ..|||
Zfish    66 HRLAAPQPVQGWEGIRNATEHPLMCLQ---------------NPDILPAIAKAIDLEVTAIGVSE 115

  Fly   130 DCLYINVWAPAKARLRHGRGANGGEHPNGKQADTDHLIHNGNPQNTTNGLPILIWIYGGGFMTGS 194
            ||||:||:.|:                  ::|:::.             ||::|||:|||...|.
Zfish   116 DCLYLNVYTPS------------------QRAESEK-------------LPVMIWIHGGGLAMGG 149

  Fly   195 A----TLDIYNADIMAAVGNVIVASFQYRVGAFGFLHLAPEMPSEFAEEAPGNVGLWDQALAIRW 255
            |    .|.:|:...:||...|:|...|||:|..|:.       |...:.|.||.|..||..|::|
Zfish   150 ACMFKELCLYDGTPLAAYEKVVVVVIQYRLGILGYF-------STGDQHAKGNWGFLDQIAALQW 207

  Fly   256 LKDNAHAFGGNPEWMTLFGESAGSSSVNAQLMSPVTRGLVKRGMMQSG--TMNAPWSHMTSEKAV 318
            ::.|..||||:|:.:|:.|||||..|.:...:||:|:||.:|.:.|||  |:...:....|..|.
Zfish   208 VQQNIEAFGGDPQSVTIAGESAGGISASLLTLSPMTKGLFQRAIFQSGVATVKGYFVKDPSTHAQ 272

  Fly   319 EIGKALINDCNCNASMLKTNPAHVMSCMRSVDAKTI--SVQQWNSYSGILSFPSAPTIDGAFLPA 381
            .|  |.|.:|:.::|.:      ::.|:|.:..:.|  :.|:    .||  ||.| .:||.|:.|
Zfish   273 VI--ANITECDFSSSEV------LVKCIREMTEEQIIKAAQK----KGI--FPGA-AVDGEFIKA 322

  Fly   382 DPMTLMKTADLKDYDILMGNVRDEGTYFLLYDFIDYFDKDDATALPRDKYLEIMNNIFGKATQAE 446
            .|..::|:.|.:...||:|....|..:.|...|           ||::.       :.|..|:|.
Zfish   323 QPEEILKSKDFQKVPILIGTTNHEFGWMLPQIF-----------LPKEW-------VKGMDTKAA 369

  Fly   447 REAI-IFQYTSWEGNPG------YQN---QQQIGRA----VGDHFFTCPTNEYAQALAERGASVH 497
            ::.: :.......|..|      ::|   .::|..|    :||.|...|:...|....|.|..|:
Zfish   370 KDRLGLLNADGASGANGIIADEYFKNAKTPEEIRDAFTELLGDIFMVIPSITVASYHREAGVPVY 434

  Fly   498 YYYFTHRTSTS--LWGEWMGVLHGDEIEYFFG--------QPLNNSLQYRPVERELGKRMLSAVI 552
            .|.|.|..||:  ....::...|.|::.:.||        :.|....:   .|.:|.:.::....
Zfish   435 MYEFQHGPSTANKFRPSFVKADHADDVGFVFGACFWDVHVKGLGTLTE---EENQLCRTVMKYRA 496

  Fly   553 EFAKTGNPAQDGEEWPNFS------------------KEDPVYYIFSTDDKIEKLARGPLA 595
            .|.:||:|......||.:.                  |:|.:  :|.|::..:|||..|.|
Zfish   497 NFIRTGSPNPAPVPWPVYDQSNKYLNLGLQQTEGQDLKKDKL--LFFTEELPKKLAAPPTA 555

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ace	NP_001163600.1	COesterase	41..601	CDD:278561	168/630 (27%)
ces2a	NP_001070720.1	COesterase	21..541	CDD:278561	161/610 (26%)
		Aes	<122..346	CDD:223730	82/276 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000