Protein Alignment Ace and LOC4576396

DIOPT Version :10

• Sequence 1: NP_476953.1
• Gene: Ace / 41625
• FlyBaseID: FBgn0000024
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: XP_315859.4
• Gene: LOC4576396 / 4576396
• VectorBaseID: AGAMI1_006793
• Length: 574
• Species: Anopheles gambiae
• Alignment Length: 667
• Identity: 169/667 - (25%)
• Similarity: 280/667 - (41%)
• Gaps: 173/667 - (25%)

  Fly    15 LPLPLTIPLPLVLVLSLHLSGVCGVIDRLVVQTSSGPVRGRSV-TVQGREVHVYTGIPYAKPPVE 78
            :|..:.:.|.:|.|::...:     :.|:.:|  .|.:||..: ::.|.....:.|||:|||||.
Mosquito     1 MPHRVVVILTVVFVVASAEN-----VPRVCIQ--DGCMRGSWMRSLHGERYEAFIGIPFAKPPVG 58

  Fly    79 DLRFRKPVPAEPW--HGVLDAT-RL-SATCVQERYEYFP--GFSGEEIWNPNTNVSEDCLYINVW 137
            .|||..|||.|||  ...|||: |: .|.|:|:.. :.|  |..|:          |||||:||:
Mosquito    59 PLRFANPVPNEPWADRQELDASGRIPRAPCLQKNL-FLPERGVEGK----------EDCLYLNVY 112

  Fly   138 APAKARLRHGRGANGGEHPNGKQADTDHLIHNGNPQNTTNGLPILIWIYGGGFMTGSATLDIYNA 202
            .|.|                         :.....:|.|..|..|::|:||||:.|      ||:
Mosquito   113 RPFK-------------------------VSKEGTENGTTPLATLVYIHGGGFLAG------YNS 146

  Fly   203 DIMAAV-----GNVIVASFQYRVGAFGFLHLAPEMPSEFAEEAPGNVGLWDQALAIRWLKDNAHA 262
            .::|..     ..||:.:..||:||||||       |...:.|.||.||.||..|:||::.|..|
Mosquito   147 PLVAGAEKLMDNAVILVTIAYRLGAFGFL-------STGDDAASGNFGLKDQREALRWVRRNIEA 204

  Fly   263 FGGNPEWMTLFGESAGSSSVNAQLMSPVTRGLVKRGMMQSGTMNAPWS-------HMTSEKAVEI 320
            |||:||.:|:.|.|||.:||:.|||.....||.:|.:..||....|||       .:..::|..:
Mosquito   205 FGGDPELVTVMGHSAGGASVHLQLMHLGNEGLFQRAISLSGNALTPWSAPRANPLQLAQQQARLL 269

  Fly   321 GKALINDCNCNASMLKTNPAHVMSCMRSVDAKTISVQQWNSYSGILSFP--------SAPTIDGA 377
            |         .....|.:...::..:|::|| .:.|..:..::....:|        .|.|:..|
Mosquito   270 G---------IKKPQKMSSGELVEALRAIDA-DLFVSSYKGFTNGSRYPVIVYGPVVEAATVPDA 324

  Fly   378 FLPADPMTLMKTADLKDYDILMGNVRDEGTYF---LLYDFIDYFDKDDATALPRDKYLE---IMN 436
            ||...|..|...........|.|.|.::|..|   :|.|          |...::.:.:   ::.
Mosquito   325 FLTEPPRELWARGAHLSVPWLTGIVPNDGFVFSAPILKD----------TDCSKETFAQQKTLLL 379

  Fly   437 NIFGKATQAEREAIIFQYTSWEGNPG-------YQNQQQIGRAVGDHFFTCP----TNEYAQALA 490
            |:.|.|.:.:...|:.:  .:.||..       ::|..::.:...:..|..|    ..::|....
Mosquito   380 NVLGGAKETDALPILME--RFFGNQSSIGECFTHENVDKLTKLFNEGLFVYPLTLSVRQHANHTG 442

  Fly   491 ERGASVHYYYFTHRTSTSLWGEWM---------GVLHGDEIEYFFGQPL------NNSLQYRPVE 540
            .: |.::.|.|.::...|....::         |::|.||:.|....|:      .||     .:
Mosquito   443 TK-APIYLYRFNYKGPHSYSSIFVPDRDELQNFGIVHCDELIYILRAPILFPDFRRNS-----PD 501

  Fly   541 RELGKRMLSAVIEFAKTGN-PAQDGE-------EWP-------NFSKEDPV---YYIFSTDDKIE 587
            .::.:.|...:::||:||. |..||:       |:|       :.|.|:||   |..|...|..:
Mosquito   502 AKVTQVMTKLIVDFARTGTAPTGDGDSDRVSDSEFPQALELTNSNSTEEPVLKKYINFYDADMFD 566

  Fly   588 KLARGPLAARCSFWNDY 604
                        ||..:
Mosquito   567 ------------FWTRF 571

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ace	NP_476953.1	COesterase	43..601	CDD:395084	162/634 (26%)
LOC4576396	XP_315859.4	None