Protein Alignment Ace and LOC4576394

DIOPT Version :10

• Sequence 1: NP_476953.1
• Gene: Ace / 41625
• FlyBaseID: FBgn0000024
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: XP_001237725.3
• Gene: LOC4576394 / 4576394
• VectorBaseID: AGAMI1_012689
• Length: 580
• Species: Anopheles gambiae
• Alignment Length: 673
• Identity: 177/673 - (26%)
• Similarity: 278/673 - (41%)
• Gaps: 180/673 - (26%)

  Fly    20 TIPLPLVLVLSLHLSGVCGVIDRLVVQTSSGPVRGRSVT-VQGREVHVYTGIPYAKPPVEDLRFR 83
            ::.:.|:::....|..|.|.:....|.|..|.:.|.|:| .:......:.|||||||||..|||:
Mosquito     4 SVVMKLLVIFGAVLVTVGGQLKHPRVCTDDGCLLGTSMTDTKNLRFDAFVGIPYAKPPVGKLRFK 68

  Fly    84 KPVPAEPWHGVLDATRLSATCVQERYEYFPGFSGEEIWNPNTNVSEDCLYINVWAPAKARLRHGR 148
            ||:|.|||....:||.....|:|:.: ..||       .|... .|:|||:||:.|.
Mosquito    69 KPIPIEPWTEDYNATESKPACLQKSF-LLPG-------QPIVG-DENCLYLNVYRPK-------- 116

  Fly   149 GANGGEHPNGKQADTDHLIHNGNPQNTTNGLPILIWIYGGGFMTGSATLDIYNADIMAAVGNVIV 213
             .||...|                      ||::::|:|||:..|||...:|..:.:.|...||:
Mosquito   117 -GNGSAVP----------------------LPVMVFIHGGGYFFGSADPQLYGPERILATKQVIL 158

  Fly   214 ASFQYRVGAFGFLHLAPEMPSEFAEEAPGNVGLWDQALAIRWLKDNAHAFGGNPEWMTLFGESAG 278
            .:.|||:|..|||       |.....|.||.|:.||.||:||:..:..||||:|..:||||||||
Mosquito   159 VTLQYRLGVLGFL-------STGDAHATGNYGMLDQVLALRWVNRHIGAFGGDPHSVTLFGESAG 216

  Fly   279 SSSVNAQLMSPVTRGLVKRGMMQSGTMNAPWS-------HMTSEKAVEIGKALINDCNCNASMLK 336
            .:||...:|||::.||.:|.::.||:..|.||       .:..::|..:|.:       .|..|.
Mosquito   217 GASVQLHMMSPLSVGLFQRAIIMSGSALAVWSLPIQDPLALARKQAKLVGVS-------EADELT 274

  Fly   337 TNPAHVMSCMRSVDAKTIS-----VQQWNSYSGILSFPSAPTIDGA-------FLPADPMTLMKT 389
            |  |.::..::.:|||.::     ::.|..:..::   ..||:.||       |||.||..|...
Mosquito   275 T--AELVDVLQYLDAKVLTASMPHLRTWFEHPIVM---YRPTVQGASVPSEERFLPDDPRKLWAE 334

  Fly   390 ADLKDYDILMGNVRDEGTYFLL-----YDFIDYFDKDDATAL-------PRDKYLE-IMNNIFGK 441
            ....|..|::|.|.:||....|     ...::.|:::....|       ..|..|| :....|.|
Mosquito   335 GRYVDIPIMIGTVPNEGAVVSLAIVHNETILEQFNENLKELLVPVLAINGTDSVLEQLKGRYFPK 399

  Fly   442 ATQAEREAIIFQYTSWEGNPGYQNQQQIGRAVGDHFFTCPT----NEYAQA--LAERGASVHYYY 500
            ||.          ..|...   .|..|..:.:.|.|...||    .:||.:  .:.|..:::.:.
Mosquito   400 ATN----------NRWIKE---DNADQFTKMMSDAFIKYPTIKTLLQYANSNQTSCRDTTLYSFE 451

  Fly   501 FTHRTS-TSLW---GEWMGVLHGDEIEYFFGQPLNNSLQYRPVERELGKRMLSAVIEFAKTGNPA 561
            |..|.| :||:   ....||.|.||:.|.:                   ||:
Mosquito   452 FEGRHSFSSLYIQSNASHGVCHQDELLYLY-------------------RMI------------- 484

  Fly   562 QDGEEWPNFSKEDPVYYIFSTDDKIEKLARGPLAARCSFWNDYLPKVRS------WAGTCDGDS- 619
               :.:|:|..:.|     .|:             .|:.|.::|....|      .:.:||.::
Mosquito   485 ---DLFPDFPPDSP-----ETE-------------MCNAWTEFLVNFASNETRPDSSRSCDANNI 528

  Fly   620 -----GSASISPRLQLLGIAALI 637
                 |:|..||.......|.|:
Mosquito   529 QTVTFGNAKSSPESTSAASAVLV 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ace	NP_476953.1	COesterase	43..601	CDD:395084	162/600 (27%)
LOC4576394	XP_001237725.3	None