Protein Alignment Ace and Nlg4

DIOPT Version :10

• Sequence 1: NP_476953.1
• Gene: Ace / 41625
• FlyBaseID: FBgn0000024
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_001369025.1
• Gene: Nlg4 / 42402
• FlyBaseID: FBgn0083975
• Length: 1437
• Species: Drosophila melanogaster
• Alignment Length: 795
• Identity: 181/795 - (22%)
• Similarity: 283/795 - (35%)
• Gaps: 250/795 - (31%)

  Fly    23 LPLVLVLSLHLSGVCGV-------IDRLVVQTSSGPVRGRSVTVQG----REVHVYTGIPYAKPP 76
            ||.||:..:|.:|....       :...:|||..|.:.|..:.:..    |.|.|:.|:|||.||
  Fly    15 LPTVLISWMHCAGASTADIYKGARLGHRIVQTRYGRLHGLILPLDSFRFLRSVEVFLGVPYATPP 79

  Fly    77 VEDLRFRKPVPAEPWHGVLDATRLSATCVQE-----------------RYEYFPGFSGEEIWNPN 124
            .:..||.......||.|:..:.:.|..|.|.                 |.||.     :.:....
  Fly    80 TKQNRFSPTRAPAPWDGIRISDKYSPVCPQRLPNIQNETAALEKMPKGRLEYL-----KRLLPFL 139

  Fly   125 TNVSEDCLYINVWAPAKARLRHGRGANGGEHPNGKQADTDHLIHNGNPQNTTNGLPILIWIYGGG 189
            .|.||||||:||::|..|      |||                        ...||::::|:|..
  Fly   140 ENQSEDCLYLNVFSPVNA------GAN------------------------EKKLPVIVFIHGES 174

  Fly   190 FMTGSATLDIYNADIMAAVGNVIVASFQYRVGAFGFLHLAPEMPSEFAEEAPGNVGLWDQALAIR 254
            |...|.  :.|:..::|:.|.|:|.:..||:|..|||:..|. |...|..|  |.||.||..|:.
  Fly   175 FEWSSG--NPYDGSVLASYGEVVVVTLNYRLGILGFLNANPN-PHAHARVA--NYGLMDQMAALH 234

  Fly   255 WLKDNAHAFGGNPEWMTLFGESAGSSSVNAQLMSP-VTRGLVKRGMMQSGTMNAPWSHMTSEKAV 318
            |::.|...|||:|..:||.|...|::.:|..:.|| :.|||..|.::.||:..:.|:.:  |..|
  Fly   235 WIQQNIQKFGGDPNSVTLAGHGTGAACINYLMTSPTMVRGLFHRAILMSGSAYSSWALV--EDPV 297

  Fly   319 EIGKALINDCNCN-ASMLKTNPAHVMSCMRSVDAKTISVQQWNSYSGILSFPSAPTIDGAFLPAD 382
            .....|..:.||. ...:..:...::.|:|.|..:.:.:....:.:.:.||  .|::||..:...
  Fly   298 LFAIKLAKEVNCTIPDDINRHHEQIVDCLRDVPLEDLYLADIQAPNFLTSF--GPSVDGVVIRPG 360

  Fly   383 PMTLMKTADLKD----------------------------------------------------- 394
            ...|    |:.|
  Fly   361 HSNL----DIDDLMARNSRRSSADSGFQSSAGGGGGQGGGAGGGGGGGSGSSFGGGYFGGSGAGT 421

  Fly   395 ------YDILMGNVRDEGTY-FLLYDFIDYF-----DKDDATALPRDKYLEIMNNIFGKATQAER 447
                  ||:|.|.|..|..: |..:|..:.|     ||...|.: |:.|...:|.||
  Fly   422 MNMGGHYDVLFGVVTGESIWRFSAHDIQNGFEGERRDKIIRTYV-RNAYNYHLNEIF-------- 477

  Fly   448 EAIIFQYTSWEGNPGYQNQQQIG------RAVGDHFFTCPTNEYAQALAER-------------- 492
            ..|:.:||.|:..    :|..|.      .|:.|..|..|.......||..
  Fly   478 YTIVNEYTDWDRT----SQHPINTRDTAVAALSDAQFVAPIVRAGDILAANSPPPVSSSSTAGSP 538

  Fly   493 GASV---------------HYYYFTHRTSTSLWGEWMGVLHGDEIEYFFGQPLNNSLQYRPVERE 542
            ||:.               ::|.|.::|....:.:.||.:||:::.|.||.||.:...:.|....
  Fly   539 GANAAASTSAGSTQPSGRCYFYVFDYQTKDGDYPQRMGTVHGEDLPYIFGAPLVDGFSHFPQNYT 603

  Fly   543 LGKRMLSAVI-----EFAKTGNP----AQDGE-------------EWPNFSKEDPVYYIFSTDDK 585
            ..:..||..:     .||:||||    .||..             .|.|:......|.......:
  Fly   604 KSETALSEAVMIFWTNFARTGNPNEHHRQDSSLPVSKERNRFRSITWENYDPLHQKYLEIGMKPR 668

  Fly   586 IEKLARGPLAARCSFWNDYLPKVR----------------------------------SWAGTCD 616
            |:...|   |.:.|.|...:|::.                                  |.|....
  Fly   669 IKNHFR---AHQLSIWLRLIPELHRAGMEDVIARHNLFRNHDDMDLYEGPVKPDPFGISTAAGAS 730

  Fly   617 GDSGSASISPRLQLL 631
            |.|.|:|.|.||.|:
  Fly   731 GSSSSSSSSSRLLLV 745

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ace	NP_476953.1	COesterase	43..601	CDD:395084	163/702 (23%)
Nlg4	NP_001369025.1	COesterase	43..681	CDD:395084	163/701 (23%)