Protein Alignment Ace and Nlg3

DIOPT Version :10

• Sequence 1: NP_476953.1
• Gene: Ace / 41625
• FlyBaseID: FBgn0000024
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_731170.2
• Gene: Nlg3 / 40912
• FlyBaseID: FBgn0083963
• Length: 1159
• Species: Drosophila melanogaster
• Alignment Length: 691
• Identity: 176/691 - (25%)
• Similarity: 276/691 - (39%)
• Gaps: 165/691 - (23%)

  Fly    44 VVQTSSGPVRGRSVTVQGRE---VHVYTGIPYAKPPVEDLRFRKPVPAEPWHGVLDATRLSATCV 105
            ::.|.:|.:.|..|.:.||.   |..|.|||||.|||.:|||..||.|..|.||..|.|.|..|.
  Fly   157 IINTRNGAISGVIVQLDGRHLDPVEAYRGIPYASPPVGNLRFMPPVSAAMWSGVKKADRFSPVCP 221

  Fly   106 QE-----------------RYEYFPGFSGEEIWNPNTNVSEDCLYINVWAPAKARLRHGRGA--- 150
            |.                 |.||.     :.:.....|.||||||:|::.|.:...|...|:
  Fly   222 QRLPDIHNETAALERMPKGRLEYL-----KRLLPYLQNQSEDCLYLNIYVPIQVGSRDSSGSSSS 281

  Fly   151 ---------NGGEHPNGKQADT-DHLIHNGNPQNTTNGLPILIWIYGGGFMTGSATLDIYNADIM 205
                     :||...:...:.| .....:|:|..    .|:|::::|..:...|.  :.|:..::
  Fly   282 SSAGSSSSGSGGSSSSSSSSSTSSSSAGSGSPAK----YPVLVFVHGESYEWNSG--NPYDGSVL 340

  Fly   206 AAVGNVIVASFQYRVGAFGFLHLAPEMPSEFAEEAPGNVGLWDQALAIRWLKDNAHAFGGNPEWM 270
            |:.|.::|.:..||:|..|||:...:..|:.    |.|.||.|...|:.|||:|..||||:|..:
  Fly   341 ASYGQILVVTINYRLGVLGFLNANTDRYSKL----PANYGLMDIIAALHWLKENIAAFGGDPNSI 401

  Fly   271 TLFGESAGSSSVNAQLMS-PVTRGLV-KRGMMQSGTMNAPWSHMTSEKAVEIGKALINDCNCNAS 333
            ||.|...|::.|:..:.| .|..||: .|.::.||:..|||| :.|..| :....:.:..||.:.
  Fly   402 TLAGHGTGAACVHFLISSMAVPEGLLFNRAILMSGSGLAPWS-LVSNPA-KYAAIVAHHVNCASD 464

  Fly   334 MLKTNP-AHVMSCMRSVDAKTISVQQWNSYSGILSFP---------SAPTIDGAFL--------- 379
            :    | ||:|.|:|.   ||:        ..:||.|         ..|:|||..:
  Fly   465 L----PHAHLMKCLRE---KTL--------DQLLSVPIRPPEFGFAFGPSIDGVVIDGGDYVPPA 514

  Fly   380 PADP-------------------------------------MTLMKTA--DLKDYDILMGNVRDE 405
            |..|                                     :.:.|||  .|..||::.|..|.|
  Fly   515 PGSPAAQAQAQASTAAGNGLGGEAGIAAAGGWGTPGQLENIVLMRKTAINKLSRYDLMAGVTRAE 579

  Fly   406 GTYFLLYDFIDYFDKDD-----ATALPRDKYLEIMNNIFGKATQAEREAIIFQYTSWE---GNPG 462
            ..:......:.|..:.|     ..|..|:.|...:|.||.        .|:.:||.||   .:|
  Fly   580 AFFSFNSGDVQYGIEADRRSRILKAYVRNTYTFHLNEIFA--------TIVNEYTDWERPVQHP- 635

  Fly   463 YQNQQQIGRAVGDHFFTCPTNEYAQALAERGASVHYYYFTHRTSTSLWGEWMGVLHGDEIEYFFG 527
            ...:.:...|:.|.....|..:.....:....:.:.|.|.::|....:.:..|.:||:::.|.||
  Fly   636 INIRDETLEALSDAQVVAPAAQTVDLHSADHRNSYLYVFDYQTRFGDYPQRQGCIHGEDLPYIFG 700

  Fly   528 QPL-----NNSLQYRPVERELGKRMLSAVIEFAKTGNPAQDGE---------------EWPNFSK 572
            .||     :.:..|...|..|.:.::.....|.:||||.:..|               ||..:..
  Fly   701 APLVGGFNHFTRNYTKTEISLSEVVMFYWSNFVRTGNPNEQMETEHGSRQERSRYKTIEWTAYES 765

  Fly   573 EDPVYYIFSTDDKIEKLARGPLAARCSFWNDYLPKVRSWAG 613
            ....|..|.|..|::...|   |.|.|||.:.:|.:....|
  Fly   766 VHKKYLNFDTKPKLKNHYR---AHRLSFWLNLIPDLHKPGG 803

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ace	NP_476953.1	COesterase	43..601	CDD:395084	172/677 (25%)
Nlg3	NP_731170.2	COesterase	154..791	CDD:395084	172/677 (25%)