Protein Alignment Ace and alpha-Est2

DIOPT Version :9

• Sequence 1: NP_001163600.1
• Gene: Ace / 41625
• FlyBaseID: FBgn0000024
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_001262345.1
• Gene: alpha-Est2 / 40908
• FlyBaseID: FBgn0015570
• Length: 566
• Species: Drosophila melanogaster
• Alignment Length: 625
• Identity: 171/625 - (27%)
• Similarity: 259/625 - (41%)
• Gaps: 155/625 - (24%)

  Fly    43 LVVQTSSGPVRG-RSVTVQGREVH-VYTGIPYAKPPVEDLRFRKPVPAEPWHGVLDATRLSATCV 105
            :::.|..|.||| :..||..:|.: .:.|||||||||.|||||.|.|.|||.|||:.|...:..:
  Fly    33 VILDTKYGQVRGLQRKTVYDKEPYFAFEGIPYAKPPVGDLRFRAPQPPEPWQGVLNCTTNRSKPM 97

  Fly   106 QERYEYFPGFSGEEIWNPNTNV---SEDCLYINVWAPAKARLRHGRGANGGEHPNGKQADTDHLI 167
            |.              |....:   |||||::||:..|..          .|.|
  Fly    98 QR--------------NMLLGIVEGSEDCLHLNVYVKALK----------SEKP----------- 127

  Fly   168 HNGNPQNTTNGLPILIWIYGGGFMTGSATLDIYNADIMAAVGNVIVASFQYRVGAFGFLHLA-PE 231
                       ||:::|||||||..|.|:.|||:.|.......|.|| ..||:.|.|||.|. |:
  Fly   128 -----------LPVIVWIYGGGFQKGEASRDIYSPDYFMKKPVVFVA-INYRLAALGFLSLKDPK 180

  Fly   232 MPSEFAEEAPGNVGLWDQALAIRWLKDNAHAFGGNPEWMTLFGESAGSSSVNAQLMSPVTRGLVK 296
            :      :.|||.||.||.:|:||:..|...|.|:|..:||.||||||:||:..:.:..||||..
  Fly   181 L------DVPGNAGLKDQVMALRWISQNIAHFNGDPNNITLMGESAGSASVHVMMTTEQTRGLFH 239

  Fly   297 RGMMQSGTMNAPW-----SHMTSEKAVEIG-KALINDCNCNASMLKTNPAHVMSCMR---SVDAK 352
            :.:||||...:.|     ::.....|..:| |....|.:..:.:.|.       |.|   ::|..
  Fly   240 KAIMQSGCALSEWVESPDNNWAFRLAQNLGYKGDEKDADVLSFLSKV-------CARQIAAIDQD 297

  Fly   353 TISVQQWNSYSGILSFPSAPTI-----DGAFLPADPMTLMKTADLKDYDILMGNVRDEGTYFLLY 412
            .|::.:..|:   |.|...|.|     |...:|.....|:..|...|..:::|....||.:  .|
  Fly   298 VINLDEVRSF---LLFAFGPVIEPYETDHCVVPKRHKDLLSEAWGNDIPVIVGGNSFEGLF--SY 357

  Fly   413 DFIDYFDKDDATALPRDKYLEIMNNIFGKATQAEREAIIFQYTSWEGNPGYQNQQQIGRAVGDHF 477
            ..:    :.|..||..      .:||..:..:        :.:|.||      |..:.|.:...:
  Fly   358 QLV----RKDPWALKN------FHNILPREVR--------ETSSLEG------QDLLVRRLKQLY 398

  Fly   478 FTCPTNEYAQALAERGASVH--YYYFTHR-----------TSTSLW-----------------GE 512
            |.....|..:.........|  .::.|||           |.|.|:                 |:
  Fly   399 FNNEMQESMEMFEALNIFSHRQIWHDTHRFILARQSYAPKTPTYLYRFDFDSPHFNQFRRLVCGD 463

  Fly   513 WM-GVLHGDEIEYFFGQPL-----NNSLQYRPVERELGKRMLSAVIEFAKTGN---PAQDGEEWP 568
            .: ||.|.||:.|.|...:     .:|::|:.:|     ||:.....||.:||   |.....:|.
  Fly   464 RIRGVAHADELSYLFYNIIASKLDKSSMEYKTIE-----RMVGMWTSFASSGNPNCPELGSAKWE 523

  Fly   569 NFS-KEDPVYYIFSTDDKIEKLARGPLAARCSFWNDYLPK 607
            ... ||:.|...|:....:| :...|.:...:.|:.:.|:
  Fly   524 AVQLKENAVEKCFNISHDLE-MRDLPESDCLAVWDTFYPR 562

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ace	NP_001163600.1	COesterase	41..601	CDD:278561	169/617 (27%)
alpha-Est2	NP_001262345.1	COesterase	32..523	CDD:278561	162/583 (28%)
		Aes	<117..>221	CDD:223730	49/142 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440445
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	1	1.000	-	-		otm46967
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.740