Protein Alignment Ace and alpha-Est4

DIOPT Version :10

• Sequence 1: NP_476953.1
• Gene: Ace / 41625
• FlyBaseID: FBgn0000024
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Alignment Length: 567
• Identity: 148/567 - (26%)
• Similarity: 234/567 - (41%)
• Gaps: 135/567 - (23%)

  Fly    41 DRLVVQTSSGPVRGRSV-TVQGREVHVYTGIPYAKPPVEDLRFRKPVPAEPWHGVLDATRLSATC 104
            |..||||:.|.|||..: ::...:.:.:.|||||.||:..|||::|...:||||:.|.::..:.|
  Fly     8 DAPVVQTTHGKVRGILLKSLYDEQFYAFDGIPYAVPPLGTLRFKEPHDLKPWHGIRDCSKPLSKC 72

  Fly   105 VQERYEYFPGFSGEEIWNPNTNVSEDCLYINVWAPAKARLRHGRGANGGEHPNGKQADTDHLIHN 169
            :|           ..........||||||:|:.....                           |
  Fly    73 LQ-----------VSTLTKEVEGSEDCLYLNISVKTL---------------------------N 99

  Fly   170 GNPQNTTNGLPILIWIYGGGFMTGSATLDIYNADIMAAVGNVIVASFQYRVGAFGFLHL-APEMP 233
            |:|      :|::::|:||.|..|.::...:..|.... .||:..|..:|:|..|||.| .|::
  Fly   100 GDP------MPVMVYIHGGAFKGGDSSRRAWGPDYFMK-ENVVYISIGHRLGPLGFLSLNDPDL- 156

  Fly   234 SEFAEEAPGNVGLWDQALAIRWLKDNAHAFGGNPEWMTLFGESAGSSSVNAQLMSPVTRGLVKRG 298
                 |.|||.||.|..||:||::.||..|.|:||.:|:||.|:||.:|...|.||.:.||..|.
  Fly   157 -----EVPGNAGLKDVILALRWIRANAANFNGDPERITIFGHSSGSMTVQLLLASPQSEGLFHRA 216

  Fly   299 MMQSG---TMNAPWSHMTSEKAVEIGKALIN-DCNCNASMLKTNPAHVMSCMRSVDAKT-ISVQQ 358
            ::.:|   .:|. ...|....|..:|....| |......:||.:||.::    |.|..| :..:|
  Fly   217 ILLAGFSMELNR-LPQMEYRLAKHLGYEGDNVDSQVLEFLLKADPALIV----SADFFTPLEKRQ 276

  Fly   359 WNSYSGILSFPSAPTID-----GAFLPADPMTLMKTADLKDYDILMGNVRDEGTYFLLYDFIDYF 418
            .:      :.|..|:|:     .|.|.|:|:.|.:|.......|::|....||  ..::.|:.
  Fly   277 GH------NMPFKPSIESYSTPNAVLLAEPIDLQRTTWSNRIPIILGANSGEG--MSIFSFVK-- 331

  Fly   419 DKDDATALPRDKYLEIMNNIFGKATQAEREAIIFQYTSW----EGNPGYQNQQQIGRAVGDHF-- 477
                            ||..:.|..|...|.::    .|    ..:||  .::|:|:|:..||
  Fly   332 ----------------MNPSWLKEFQCNPERVL----PWTLRNRCDPG--QRRQLGQALIHHFCE 374

  Fly   478 ---------------------FTCPTNEYAQALAERGASVHYYY--------FTHRTSTSLWGEW 513
                                 |....:...|:....|.:..|.|        |.......:..|.
  Fly   375 AHGHELTVDHTNGLVELFTHGFVHAMDRLIQSRLTYGQAPTYLYRFDFDSPDFNFYRIRFMGKEQ 439

  Fly   514 MGVLHGDEIEYFFGQPLNNSLQYRPVERELGKRMLSAVIEFAKTGNP 560
            .||.|.||:.|.|..|....|.....|....:|:::..::||.|.:|
  Fly   440 RGVGHVDELGYIFKLPATFKLDKSRPEFTAIRRLVAMFVQFAATSDP 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ace	NP_476953.1	COesterase	43..601	CDD:395084	147/565 (26%)
alpha-Est4	NP_524266.1	alpha/beta hydrolases	8..529	CDD:473884	148/567 (26%)