Protein Alignment Ace and Est-6

DIOPT Version :10

• Sequence 1: NP_476953.1
• Gene: Ace / 41625
• FlyBaseID: FBgn0000024
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_788500.1
• Gene: Est-6 / 39392
• FlyBaseID: FBgn0000592
• Length: 544
• Species: Drosophila melanogaster
• Alignment Length: 579
• Identity: 147/579 - (25%)
• Similarity: 249/579 - (43%)
• Gaps: 116/579 - (20%)

  Fly    21 IPLPLVLVLS-LHL-SGVCGVIDRLVVQTSSGPVRGRSVTVQGREVHVYTGIPYAKPPVEDLRFR 83
            :.|.|::||| |.| |......|.|:||...|.:|||    .....:.|..||||:||..||||.
  Fly     4 VGLGLIIVLSCLWLGSNASDTDDPLLVQLPQGKLRGR----DNGSYYSYESIPYAEPPTGDLRFE 64

  Fly    84 KPVP-AEPWHGVLDATRLSATCVQERYEYF-PGFS---GEEIWNPNTNVSEDCLYINVWAPAKAR 143
            .|.| .:.|..:.|||:....|:|  ::.| ||.:   ||          ||||.::|:.|
  Fly    65 APEPYKQKWSDIFDATKTPVACLQ--WDQFTPGANKLVGE----------EDCLTVSVYKP---- 113

  Fly   144 LRHGRGANGGEHPNGKQADTDHLIHNGNPQNTTNGLPILIWIYGGGFMTGSATLDIYNADIMAAV 208
                        .|.|:                |..|::..|:||.||.|:|..:.:. ::|..
  Fly   114 ------------KNSKR----------------NSFPVVAHIHGGAFMFGAAWQNGHE-NVMRE- 148

  Fly   209 GNVIVASFQYRVGAFGFLHLAPEMPSEFAEEAPGNVGLWDQALAIRWLKDNAHAFGGNPEWMTLF 273
            |..|:....||:|..||:       |....:.|||.||.||.||::|:|.|..:|||.|:.:.|.
  Fly   149 GKFILVKISYRLGPLGFV-------STGDRDLPGNYGLKDQRLALKWIKQNIASFGGEPQNVLLV 206

  Fly   274 GESAGSSSVNAQLMSPVTRGLVKRGMMQSGTMNAPW--SHMTSEKAVEIGKALINDCNCNASMLK 336
            |.|||.:||:.|::......|.:.....||....||  ......:|.|:|:    :..|.::...
  Fly   207 GHSAGGASVHLQMLREDFGQLARAAFSFSGNALDPWVIQKGARGRAFELGR----NVGCESAEDS 267

  Fly   337 TNPAHVMSCMRSVDAKTI--SVQQWNSYSGILSFPSAPTID-----GAFLPADPMTLMKTADLKD 394
            |:   :..|::|..|..:  :|:::..:|.:...|.:|.::     .|.:..||..::|:.....
  Fly   268 TS---LKKCLKSKPASELVTAVRKFLIFSYVPFAPFSPVLEPSDAPDAIITQDPRDVIKSGKFGQ 329

  Fly   395 YDILMGNVRDEGTY---FLLYDFIDYFDKDDATALPRDKYLEIMNN-IFGKATQAEREAIIFQYT 455
            ....:..|.::|.|   .||.:.......||.    .:::||:... :|.:.|:.:::  :..|:
  Fly   330 VPWAVSYVTEDGGYNAALLLKERKSGIVIDDL----NERWLELAPYLLFYRDTKTKKD--MDDYS 388

  Fly   456 -----SWEGNPGY--QNQQQIGRAVGDHFFTCPTNEYAQALAERGASVHYYY------------- 500
                 .:.||..:  ::..::.|...|..|...|.|......:.|.|..|.|
  Fly   389 RKIKQEYIGNQRFDIESYSELQRLFTDILFKNSTQESLDLHRKYGKSPAYAYVYDNPAEKGIAQV 453

  Fly   501 FTHRTSTSLWGEWMGVLHGDEIEYFFGQPLNNSLQYRPVERELGKRMLSAVIEFAKTGN 559
            ..:||...     .|.:|||:....| :.....::.||.|:.:.:..::.:.:||.:.|
  Fly   454 LANRTDYD-----FGTVHGDDYFLIF-ENFVRDVEMRPDEQIISRNFINMLADFASSDN 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ace	NP_476953.1	COesterase	43..601	CDD:395084	138/555 (25%)
Est-6	NP_788500.1	Esterase_lipase	29..537	CDD:238191	137/554 (25%)