DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ace and gas

DIOPT Version :9

Sequence 1:	NP_001163600.1	Gene:	Ace / 41625	FlyBaseID:	FBgn0000024	Length:	649	Species:	Drosophila melanogaster
Sequence 2:	NP_611678.1	Gene:	gas / 37572	FlyBaseID:	FBgn0034736	Length:	566	Species:	Drosophila melanogaster

Alignment Length:	578	Identity:	152/578 - (26%)
Similarity:	233/578 - (40%)	Gaps:	136/578 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 VIDRLVVQ------------TSSGPVRG--RSVTVQGREVHVYTGIPYAKPPVEDLRFRKPVPAE 89
            :|...|||            |..|.::|  |.....|...:.:.|||:|:|||.:||||.|.|..
  Fly    17 IIGHKVVQYKLGTGQTKELATKYGQLKGQQRRTLYDGEPYYSFEGIPFAQPPVGELRFRAPQPPS 81

  Fly    90 PWHGVLDATRLSATCVQERYEYFPGFSGEEIWNPNTNV---SEDCLYINVWAPAKARLRHGRGAN 151
            .|.||.|.|......:|.              |..||.   ||||||:||:|   .||
  Fly    82 SWQGVRDCTYAREKPMQR--------------NSITNAAEGSEDCLYLNVYA---KRL------- 122

  Fly   152 GGEHPNGKQADTDHLIHNGNPQNTTNGLPILIWIYGGGFMTGSATLDIYNADIMAAVGNVIVASF 216
              |.|                    ..||:::||:||||..|.|:.::|..|.... .::::.:.
  Fly   123 --ESP--------------------KPLPVMVWIFGGGFQVGGASRELYGPDYFMK-HDILLVTI 164

  Fly   217 QYRVGAFGFLHLAPEMPSEFAEEAPGNVGLWDQALAIRWLKDNAHAFGGNPEWMTLFGESAGSSS 281
            .||||..|||.|     .:...:.|||.||.||..|:||:|:|..:|.|:||.:|:||||||.:|
  Fly   165 NYRVGVLGFLSL-----KDKELKIPGNAGLKDQIQALRWVKENIASFNGDPESITVFGESAGGAS 224

  Fly   282 VNAQLMSPVTRGLVKRGMMQSGTMNAPWSHMTSEK-AVEIGKAL--INDCNCNASMLKTNPAHVM 343
            .:..:.:...|||..|.::|||:....|:.....| ...:||.|  ..:......:|:.......
  Fly   225 THILMQTEQARGLFHRAIVQSGSALCAWATQPDRKWPQRLGKELGYAGNLESEKELLEFFQQIPA 289

  Fly   344 SCMRSVDAKTISVQQWNSYSGILSFPSAPTI-----DGAFLPADPMTLMKTADLKDYDILMGNVR 403
            |.:.......::.::...|. ||:|  ||.|     |...:|......:.:|......:::|...
  Fly   290 SKLAQYCNSIVTQEEQRDYE-ILAF--APVIEPYVGDDCVIPKSQQEQLSSAWGNSIPMIIGGTS 351

  Fly   404 DEGTY----------FLLYDFIDYFDKDDATALPRDKYLEIMNNI----FGKATQAEREA----- 449
            .||.:          ::|..|.....|....|:.:::..|::..:    |....:|..|.
  Fly   352 FEGLFSYRTTLDDPLYMLSAFEAIIPKQVRDAIDKEELAEMVRRLKKSYFDDPDRASMELYECLH 416

  Fly   450 IIFQYTSWEGNPGYQNQQQIGRAVGDHFFTCPTNEYAQALAERGASVHYY-------YFTHRTST 507
            |:.....|         ..|.|.:           .|:.........:.|       :|.|....
  Fly   417 ILSIKNFW---------HDIHRTL-----------LARLAYATNLPTYLYRFDMDSPHFNHYRIL 461

  Fly   508 SLWGEWMGVLHGDEIEYFFGQPLN-----NSLQYRPVERELGKRMLSAVIEFAKTGNP 560
            ....:..||.|.|:|.|.|...|:     ||.:||.:||.:|  |.::   ||.||:|
  Fly   462 KCGKKVRGVCHADDISYMFYGILSSKLDKNSPEYRTIERLVG--MWTS---FATTGDP 514

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ace	NP_001163600.1	COesterase	41..601	CDD:278561	151/576 (26%)
gas	NP_611678.1	COesterase	28..534	CDD:278561	148/567 (26%)
gas	NP_611678.1	Aes	<117..>222	CDD:223730	48/142 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440443
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	1	1.000	-	-		otm46967
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.740