Protein Alignment Ace and LOC3291301

DIOPT Version :10

• Sequence 1: NP_476953.1
• Gene: Ace / 41625
• FlyBaseID: FBgn0000024
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: XP_554880.4
• Gene: LOC3291301 / 3291301
• VectorBaseID: AGAMI1_009894
• Length: 591
• Species: Anopheles gambiae
• Alignment Length: 631
• Identity: 138/631 - (21%)
• Similarity: 243/631 - (38%)
• Gaps: 150/631 - (23%)

  Fly     1 MAISCRQSRVLPMSLPLPLTIPLPLVLVLSLHLSGVCGV----IDRLVVQTSSGPVRGRSVTVQG 61
            ||||..::.:|....|..|   |.::...|...|.:.|.    ::.:|.....|.::|.:.....
Mosquito     1 MAISISRTLLLRSHRPSKL---LTVLCSSSKRYSTMAGPESTDLNPVVELPGLGKLKGSTTRGAW 62

  Fly    62 REVHV--YTGIPYAKPPVEDLRFRKPVPAEPWHGVLDAT----------RLSATCVQERYEYFPG 114
            ..|::  :..:.||:|...:.||:.|||.:||.||:|.:          |:.....::|.:..
Mosquito    63 TGVNILQFLNVRYAEPATGERRFKPPVPVQPWDGVMDVSEPKLGSPVYKRMKLLTEEQRAQNL-- 125

  Fly   115 FSGEEIWNPNTNVSEDCLYINVWAPAKARLRHGRGANGGEHPNGKQADTDHLIHNGNPQNTTNGL 179
                          |||:.::|:.      :..||..
Mosquito   126 --------------EDCINLSVFT------KDLRGRK---------------------------- 142

  Fly   180 PILIWIYGGGFMTGSATLDIYNAD---IMAAVGNVIVASFQYRVGAFGFLHLAPEMPSEFAEEAP 241
            |::::::||||..|:    |::..   ||..  :|::...|||:||.|||       ....::.|
Mosquito   143 PVIVYVHGGGFYDGA----IFHYPPNYIMEK--DVVLVVPQYRLGALGFL-------CSNTKQIP 194

  Fly   242 GNVGLWDQALAIRWLKDNAHAFGGNPEWMTLFGESAGSSSVNAQLMSPV--TRGLVKRGMMQSGT 304
            ||.|:.|..||..|::.....|||:|..:|...:|:|::.|::...||:  |..|.:|.::|||.
Mosquito   195 GNAGVMDVVLAFEWVQKYISHFGGDPGQVTAMAQSSGAAMVSSMTYSPLVDTERLFQRLILQSGN 259

  Fly   305 MNAPWSHMTSEKAVEIGKALINDCNCN-----ASMLKTNPA-HVMSCMRSVDAKTISVQQWNSYS 363
            .:..|....|.:.           ||.     |...:..|. .|...:..:|..:: ::.:..:.
Mosquito   260 CHGSWVWDRSPER-----------NCRDIAGFAGFDRKAPLDQVERFLMELDIFSL-MKAFTQHY 312

  Fly   364 GILSFPSAPTIDGA---------FLPADPMTLM-KTADLKDYDILMGNVRDEGTYFLLYDF-IDY 417
            .:.:.....||.||         ..|.:|..:| |....|:..:|.|..|.:||:..|..| |..
Mosquito   313 RLRTPNGTDTIGGARMVFNDPNGLFPENPYFIMRKGGGRKNMPLLTGVTRHDGTFAFLEVFNILL 377

  Fly   418 FDKDDATALPRDKYLEI------MNNIFG--KATQAEREAIIFQYTSWEGNPGYQNQQQIG---- 470
            |.|     |..|.::.|      :|.:.|  ..:...|...:.|:.:.|.......:|.:.
Mosquito   378 FKK-----LIGDPHITIHRMVDEVNQVLGVDDPSCTVRTLTMAQFFTHEQLASGDLRQLLAGFCD 437

  Fly   471 ------------RAVGDHFFTCPTNEYAQALAERGASVHYYYFTHRTSTSLWGEWMGVLHGDEIE 523
                        :...::....|...|..:....|....:.|....::....|   ||.|.:::.
Mosquito   438 HTADVLIKGPVLKMAQNNAMYLPDQTYLYSFDYAGEHTRFGYGGDTSAIPFDG---GVHHSNDLM 499

  Fly   524 YFFGQPLNNSLQYRPVERELGKRMLSAVIEFAKTGNP-AQDGEEWP 568
            |.|..| .|:.|....:..:.|||:.....||.:|.| |.|...||
Mosquito   500 YLFPYP-PNAAQLNERDTAVAKRMVDLWTSFAISGKPEANDVPAWP 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ace	NP_476953.1	COesterase	43..601	CDD:395084	127/585 (22%)
LOC3291301	XP_554880.4	None