Protein Alignment Ace and Ces2i

DIOPT Version :10

• Sequence 1: NP_476953.1
• Gene: Ace / 41625
• FlyBaseID: FBgn0000024
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: XP_008758816.2
• Gene: Ces2i / 292152
• RGDID: 1565045
• Length: 558
• Species: Rattus norvegicus
• Alignment Length: 614
• Identity: 175/614 - (28%)
• Similarity: 274/614 - (44%)
• Gaps: 113/614 - (18%)

  Fly    37 CGVIDRLVVQ-------------TSSGPVRGRSVTVQGRE--VHVYTGIPYAKPPVEDLRFRKPV 86
            ||::  |::|             |.:|.|||..|.|:..:  ||.:.|||:|||||..|.|..|.
  Rat    15 CGLL--LLLQHVHGQDSASPIRNTQTGQVRGSFVHVKDTKSGVHTFLGIPFAKPPVGPLHFAPPE 77

  Fly    87 PAEPWHGVLDATRLSATCVQERYEYFPGFSGEEIWNPNTNVSEDCLYINVWAPAKARLRHGRGAN 151
            ..|||.||.|.|.....|:|............::....|.:||||||:|::.||.||    .|:|
  Rat    78 DPEPWSGVRDGTSQPDMCLQTDIMKEDFIKEMKLTMHPTPMSEDCLYLNIYTPAHAR----EGSN 138

  Fly   152 GGEHPNGKQADTDHLIHNGNPQNTTNGLPILIWIYGGGFMTGSATLDIYNADIMAAVGNVIVASF 216
                                       ||:::||:|||.:.|||::::  |..:||...:::.:.
  Rat   139 ---------------------------LPVMVWIHGGGLVLGSASMNV--ASTLAATEEIVIVAI 174

  Fly   217 QYRVGAFGFLHLAPEMPSEFAEEAPGNVGLWDQALAIRWLKDNAHAFGGNPEWMTLFGESAGSSS 281
            |||:|..||.       |...|.|.||.|..||..|:.|::.|...||||...:|:||.|||.:|
  Rat   175 QYRLGILGFF-------STGDEHARGNWGYLDQVAALCWVQQNIAYFGGNHGKVTIFGVSAGGTS 232

  Fly   282 VNAQLMSPVTRGLVKRGMMQSGTMNAPWSHMTSEKAVEIGKALINDCNCNASMLKTNPAHVMSCM 346
            |::.::||:::||....:||||....|  .:.|:.:..:.|.:.|...|.||    :...::.|:
  Rat   233 VSSHVVSPMSKGLFHGAIMQSGVALLP--DLISDTSEVVYKTVANLSGCEAS----DSEALIRCL 291

  Fly   347 RSVDAKTISV--QQWNSYSGILSFPSAPTIDGAFLPADPMTLMKTADLKDYDILMGNVRDE-GTY 408
            |:...:.|..  |.:....|:        :||.|||..|..|:.:.|......::|...|| |..
  Rat   292 RAKSKQEILAINQVFKMIPGV--------VDGKFLPKHPQELLASGDFHPVPSIIGVNTDECGLG 348

  Fly   409 FLLYDFIDYFDKDDATALPRDKYLEIMNNIFGKATQAER-------EAIIFQYTSWEGNPGYQNQ 466
            ..::..:|:..|    .:.||....::     |:|.|:.       :.|:.:|.....:| ...|
  Rat   349 VPMFMGLDHIIK----KITRDTLPTVL-----KSTAAQMMLPPECIDLIMEEYMGDTEDP-ETLQ 403

  Fly   467 QQIGRAVGDHFFTCPTNEYAQALAERGASVHYYYFTHRTS--TSLWGEWMGVLHGDEI-----EY 524
            :|....:||..|..|..|.|. .....|.|::|.|.|..|  ..:....:...|||:|     .|
  Rat   404 EQFKEMLGDFMFVIPALEVAH-FQRSQAPVYFYEFQHLPSFIKQVRPSHVKADHGDDILFVFSSY 467

  Fly   525 FFGQPLNNSLQYRPVERE--LGKRMLSAVIEFAKTGNP-AQDGEEWPNFSKEDPVYYIFSTDDKI 586
            |:|      :.:...|.|  |.:|::.....||:.||| ::|...||.....:. |...:|...:
  Rat   468 FWG------MNFDITEEEELLKRRVMKYWANFARNGNPNSEDLPYWPVLDHNEQ-YLQLNTQPAV 525

  Fly   587 EKLARGPLAARCSFWNDYLP-KVRSWAGT 614
               .|...|.|..||...|| |::...|:
  Rat   526 ---GRALKARRLQFWTKTLPQKIQELKGS 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ace	NP_476953.1	COesterase	43..601	CDD:395084	167/592 (28%)
Ces2i	XP_008758816.2	COesterase	30..537	CDD:395084	165/581 (28%)