Protein Alignment Ace and Ces1c

DIOPT Version :10

• Sequence 1: NP_476953.1
• Gene: Ace / 41625
• FlyBaseID: FBgn0000024
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: XP_006255234.2
• Gene: Ces1c / 24346
• RGDID: 2571
• Length: 551
• Species: Rattus norvegicus
• Alignment Length: 607
• Identity: 170/607 - (28%)
• Similarity: 272/607 - (44%)
• Gaps: 136/607 - (22%)

  Fly    44 VVQTSSGPVRGRSVTVQG--REVHVYTGIPYAKPPVEDLRFRKPVPAEPWHGVLDATRLSATCVQ 106
            ||.|:.|.|.|:.|:::|  :.|.|:.|:|:||||:..|||..|.|||||..|.:.|.....|.|
  Rat    27 VVDTTKGKVLGKYVSLEGFTQPVAVFLGVPFAKPPLGSLRFAPPEPAEPWSFVKNTTTYPPMCSQ 91

  Fly   107 ERYEYFPGF----------SGEEIWNPNTNVSEDCLYINVWAPAKARLRHGRGANGGEHPNGKQA 161
            :      |.          :|:|  |.....||||||:|:::||..
  Rat    92 D------GVVGKLLADMLSTGKE--NIPLEFSEDCLYLNIYSPADL------------------- 129

  Fly   162 DTDHLIHNGNPQNTTNG-LPILIWIYGGGFMTGSATLDIYNADIMAAVGNVIVASFQYRVGAFGF 225
                         |.|. ||:::||:|||.:.|.|:  .|:...::|..||:|.:.|||:|.:|.
  Rat   130 -------------TKNSRLPVMVWIHGGGLIIGGAS--PYSGLALSAHENVVVVTIQYRLGIWGL 179

  Fly   226 LHLAPEMPSEFAEEAPGNVGLWDQALAIRWLKDNAHAFGGNPEWMTLFGESAGSSSVNAQLMSPV 290
            .       |...|.:.||....||..|:||::||...|||||:.:|:||||||..||:..::||:
  Rat   180 F-------STGDEHSRGNWAHLDQLAALRWVQDNIANFGGNPDSVTIFGESAGGVSVSVLVLSPL 237

  Fly   291 TRGLVKRGMMQSGTMNAPWSHMTSEKAVEIGKALINDCNCNASMLKTNPAHVMSCMR---SVDAK 352
            .:.|..|.:.:||.:........:.:||....|.::.||      .|:.|.::.|:|   ..:..
  Rat   238 AKNLFHRAISESGVVLTTNLDKKNTQAVAQMIATLSGCN------NTSSAAMVQCLRQKTEAELL 296

  Fly   353 TISVQQWNSYSGILSFPSAPTIDGAFLPADPMTLM--KTADLKDYDI-------------LMGNV 402
            .::|:..|:       ..:..|||..||..|..::  |:.:...|.:             :|||:
  Rat   297 ELTVKLDNT-------SMSTVIDGVVLPKTPEEILTEKSFNTVPYIVGFNKQEFGWIIPTMMGNL 354

  Fly   403 RDEGTYFLLYDFIDYFDKDDATALPR--DKYLEIMNNIFGKATQAEREAIIFQYTSWEGNPGYQN 465
            ..||.          .::..|::|.|  ...|.|..::.        .|||.:|.....:|. :.
  Rat   355 LSEGR----------MNEKMASSLLRRFSPNLNISESVI--------PAIIEKYLRGTDDPA-KK 400

  Fly   466 QQQIGRAVGDHFFTCPTNEYAQALAERGASVHYYYFTHRTS-------TSLWGEWMGVLHGDEIE 523
            ::.:.....|.||..|....:::|.:.||..:.|.|.:|.|       .::.|:     |||||.
  Rat   401 KELLLDMFSDVFFGIPAVLMSRSLRDAGAPTYMYEFQYRPSFVSDQRPQTVQGD-----HGDEIF 460

  Fly   524 YFFGQPLNNSLQYRPVERE--LGKRMLSAVIEFAKTGNPAQDG-EEWPNFSKEDPVYYIFSTDDK 585
            ..||.|.   |:....|.|  |.|.::.....||:.|||..:| ..||.:.:::....|.:|..:
  Rat   461 SVFGTPF---LKEGASEEETNLSKLVMKFWANFARNGNPNGEGLPHWPEYDQKEGYLQIGATTQQ 522

  Fly   586 IEKLARGPLAARCSFWNDYLPK 607
            .:||....:|    ||.:.|.|
  Rat   523 AQKLKGEEVA----FWTELLAK 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ace	NP_476953.1	COesterase	43..601	CDD:395084	166/599 (28%)
Ces1c	XP_006255234.2	COesterase	24..534	CDD:395084	166/599 (28%)