Protein Alignment Ace and Ces2b

DIOPT Version :9

• Sequence 1: NP_001163600.1
• Gene: Ace / 41625
• FlyBaseID: FBgn0000024
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_937814.1
• Gene: Ces2b / 234669
• MGIID: 2448547
• Length: 556
• Species: Mus musculus
• Alignment Length: 598
• Identity: 163/598 - (27%)
• Similarity: 266/598 - (44%)
• Gaps: 93/598 - (15%)

  Fly    26 VLVLSLHLSGVCGVIDRLVVQTSSGPVRGRSVTVQGRE--VHVYTGIPYAKPPVEDLRFRKPVPA 88
            :|:|..|:.|........:..|.:|.|||..|.|:..:  ||.:.|||:|||||..|||..|...
Mouse    17 LLLLLGHVQGQDSPEASPIRNTHTGQVRGSLVHVKDTKAGVHTFLGIPFAKPPVGPLRFAPPEAP 81

  Fly    89 EPWHGVLDATRLSATCVQERYEYFPGFSGE-EIWNPNTNVSEDCLYINVWAPAKARLRHGRGANG 152
            |||.||.|.|...|.|:|..     |...| ::..|..:.||||||:|::.||.|
Mouse    82 EPWSGVRDGTAHPAMCLQNL-----GVMKEIKLKLPPVSTSEDCLYLNIYTPAHA---------- 131

  Fly   153 GEHPNGKQADTDHLIHNGNPQNTTNGLPILIWIYGGGFMTGSATLDIYNADIMAAVGNVIVASFQ 217
                           |.|      :.||:::||:|||.:.|.|::  |:..::||:.:::|.:.|
Mouse   132 ---------------HEG------SNLPVMVWIHGGGLVAGMASM--YDGSLLAAIEDLVVVTIQ 173

  Fly   218 YRVGAFGFLHLAPEMPSEFAEEAPGNVGLWDQALAIRWLKDNAHAFGGNPEWMTLFGESAGSSSV 282
            ||:|..||.       |...:.|.||.|..||..|:||::.|...|||.|:.:|:||||||.:||
Mouse   174 YRLGVLGFF-------STGDQHARGNWGFLDQVAALRWIQQNIAHFGGKPDRVTIFGESAGGTSV 231

  Fly   283 NAQLMSPVTRGLVKRGMMQSGTMNAPWSHMTSEKAVEIGKALINDCNCNASMLKTNPAHVMSCMR 347
            ::.::||:::||....:|:||....|:....:.:.|....|.::.|....|      ..::.|:|
Mouse   232 SSHVVSPMSKGLFHGAIMESGVALLPYLITDTSEMVSTTVAKLSGCEAMDS------EALVRCLR 290

  Fly   348 -SVDAKTISVQQWNSYSGILSFPSAPTIDGAFLPADPMTLMKTADLKDYDILMGNVRDEGTYFL- 410
             ..:|:.:::.:.     :...|:  .:||.|.|..|..|:.:.|......::|...||..:.:
Mouse   291 GKSEAEILAINKL-----VQMIPA--VVDGEFFPRHPKELLASEDFHPVPSIIGVNNDEFGWTIP 348

  Fly   411 ----LYDFIDYFDKDDATALPRDKYLEIMNNIFGKATQAEREAIIFQYTSWEGNPGYQNQQQIGR 471
                ....|....:::..|:.::...::|       ...|...::.:....:.......|.|...
Mouse   349 VVMGSAQTIKEITRENLQAVLKNTTAQLM-------LPPECSDLLMEEYMGDTEDAQTLQIQFTE 406

  Fly   472 AVGDHFFTCPTNEYAQALAERGASVHYYYFTHRTS-------TSLWGEWMGVLHGDEIEYFFGQP 529
            .:.|..|..|..:.|. .....|||::|.|.|:.:       |.:..:     |.|||.:.||..
Mouse   407 MMEDFMFVIPALQVAY-FQRSHASVYFYEFQHQIASLKDVRPTHVKAD-----HADEIPFVFGYF 465

  Fly   530 L-NNSLQYRPVERELGKRMLSAVIEFAKTGNPAQDG-EEWPNFSKEDPVYYIFSTDDKIEKLARG 592
            . :..|.:...|:.|.:||:.....||:.|||..:| ..|| ....|..|....|...:   .|.
Mouse   466 FWDMKLDFTEGEKLLSRRMMKYWANFARHGNPNSEGLPYWP-VMDHDEQYLQLDTQPAV---GRA 526

  Fly   593 PLAARCSFWNDYL 605
            ..:.|..||...|
Mouse   527 LKSRRLQFWTKTL 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ace	NP_001163600.1	COesterase	41..601	CDD:278561	156/577 (27%)
Ces2b	NP_937814.1	COesterase	34..535	CDD:365897	156/575 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810