Protein Alignment Ace and cest-31

DIOPT Version :10

• Sequence 1: NP_476953.1
• Gene: Ace / 41625
• FlyBaseID: FBgn0000024
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_504692.3
• Gene: cest-31 / 187304
• WormBaseID: WBGene00019653
• Length: 541
• Species: Caenorhabditis elegans
• Alignment Length: 627
• Identity: 158/627 - (25%)
• Similarity: 257/627 - (40%)
• Gaps: 162/627 - (25%)

  Fly    22 PLPLVLVLSLHLSGVCGVIDRLVVQTSSGPVRGRSVTVQGREVHVYTGIPYAKPPVEDLRFRKPV 86
            |.||:.||:                ::.|||:|........|||.|.|||||:||:..|||:|||
 Worm    10 PKPLLNVLN----------------STCGPVQGNLYRHGNEEVHGYLGIPYAQPPIGILRFKKPV 58

  Fly    87 PAEPWHGVLDATRLSATCVQERYEYFPGFSGEEIWNPNTNVSED--CLYINVWAP---AKARLRH 146
            .|:.|....|.|:....|...      |...|.:..|||::.::  ||.:||:.|   .|...:|
 Worm    59 SADVWTETRDCTKYGPRCPPS------GMLYENLQLPNTDIPDEANCLSLNVFCPQWEIKQSAKH 117

  Fly   147 GRGANGGEHPNGKQADTDHLIHNGNPQNTTNGLPILIWIYGGGFMTGSATLDI--YNADIMAAVG 209
                                             |::|:|:||||.. ||:.|.  |:......:.
 Worm   118 ---------------------------------PVMIFIHGGGFEL-SASKDYCDYSLSGTLPLK 148

  Fly   210 NVIVASFQYRVGAFGFLHLAPEMPSEFAEEAPGNVGLWDQALAIRWLKDNAHAFGGNPEWMTLFG 274
            :|||.:..|||||.|||....       :...||.||||..||::|:..:..:|||:|:.:||||
 Worm   149 DVIVVTVNYRVGALGFLTTGD-------DSCRGNFGLWDLTLALKWVSTHISSFGGDPKNVTLFG 206

  Fly   275 ESAGSSSVNAQLMSPVTRGLVKRGMMQSGTMNAPWSHMTSEK----AVEIGKALINDCNCNASML 335
            :|||:...:...:||.:|.|..:.::.||:.:.|::..|.|.    .:|..::.....:.:|.:|
 Worm   207 QSAGAVCADLLNLSPYSRDLFHKLIIMSGSAHVPFAIRTEENQALVCMEYARSRGFSGSGSAELL 271

  Fly   336 -------------KTNPAHVMSCMRSVDAKTISVQQWNSYSGILSFPSAPTIDGAFLPADPMTLM 387
                         ||...|           |:|:.        |||  ||.:||.|.| .|:..:
 Worm   272 EFFENLPIEKLLEKTGLKH-----------TVSID--------LSF--APNLDGDFFP-KPLEEL 314

  Fly   388 KTADLKDYDILMGNVRDEG--TYFLLYDF----------IDYFDKDDATALPRDKYLEIMNNIFG 440
            : .:.:...:::|.:.|||  |.|...||          ::...:.|....|.:....|||....
 Worm   315 R-RETRKKPVIVGMMEDEGLITAFADGDFTTCEENFKRRVESEYRGDVVENPENVQKNIMNFYTN 378

  Fly   441 KATQAEREAIIFQYTSWEGNPGYQNQQQIGRAVGDHFFTCPTNEYAQALAERGASVHYYYFTHRT 505
            ...::|...::               ..||.:|    :.......|::||..|..|::|.|
 Worm   379 YCDESEERKLV---------------DYIGHSV----YNAGVLLSAESLARAGNCVYFYVF---- 420

  Fly   506 STSLWG-----------EWMGVLHGDEIEYFFGQPLNNSLQYRPVERELGKRMLSAVIEFAKTGN 559
              ..|.           .:.|..|..|:.|..|:.:.:.......:.::.:.|.:....|||.||
 Worm   421 --DFWNPDGFGPVGSIVPFKGAAHCSELRYIIGEGVYSKFDANEKDLKMMEYMTTMFTNFAKYGN 483

  Fly   560 PAQDG-EEWPNFSKEDPVYYIFSTDDKIEKLARGPLAARCSF 600
            |...| ..|..:::....::|.|||.:::...:   ..||.|
 Worm   484 PNIPGVTNWETYTEGSRHFHIDSTDSEMKDSFQ---ENRCQF 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ace	NP_476953.1	COesterase	43..601	CDD:395084	153/606 (25%)
cest-31	NP_504692.3	COesterase	16..522	CDD:395084	154/619 (25%)