Protein Alignment Ace and cest-7

DIOPT Version :10

• Sequence 1: NP_476953.1
• Gene: Ace / 41625
• FlyBaseID: FBgn0000024
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_001257187.1
• Gene: cest-7 / 182819
• WormBaseID: WBGene00007693
• Length: 606
• Species: Caenorhabditis elegans
• Alignment Length: 596
• Identity: 142/596 - (23%)
• Similarity: 235/596 - (39%)
• Gaps: 162/596 - (27%)

  Fly    44 VVQTSSGPVRG-RSVTVQGREVHVYTGIPYAKPPVEDLRFRKPVPAEPWHGVLDATRLSATCVQE 107
            |:.|:.|.||| ...:.:....:::.|||:||||:..|||..|.....|:||||.::.||.|:
 Worm    39 VLNTNYGKVRGITDFSDKRNHKYIFKGIPFAKPPLGLLRFALPEEPNTWNGVLDGSKYSAACL-- 101

  Fly   108 RYEYFPGFSGEEIWN-PNTNVSEDCLYINVWAPAKARLRHGRGANGGEHPNGKQADTDHLIHNGN 171
                    |...:.: ...|:||||||||::.....                       |.|.
 Worm   102 --------SNSSLASAQQENISEDCLYINIFTSEYC-----------------------LAHK-- 133

  Fly   172 PQNTTNGLPILIWIYGGGFMTGSATL--DIYNADIMAAVGNVIVASFQYRVGAFGFLHLAPEMPS 234
                   .|:|::.:||.|...|||:  |.:..:.....| ::.|...||:|.||..:|..:
 Worm   134 -------CPVLVYYHGGSFNLDSATMFPDKFILERYVDSG-IVFAIPAYRLGVFGQFYLGEQ--- 187

  Fly   235 EFAEEAPGNVGLWDQALAIRWLKDNAHAFGGNPEWMTLFGESAGSSSVNAQLMS---PVTRGLVK 296
               ...|.|:.:.|...::.::.||..:|||:|.::||.|.|:|...|||...|   ...:.|.:
 Worm   188 ---GIVPANLLIHDCIRSLNFVHDNIASFGGDPNYVTLMGHSSGGQLVNAMGFSNQIDPEKKLFQ 249

  Fly   297 RGMMQSGTMNAPWSHMTSEKAVEIGKA--LINDCNCNASMLKTNPAHVMSCMRSVDA-KTISVQQ 358
            :.::.|..      .|...:.::||.:  :....||.:.    |...::.|||::|| :.:..|.
 Worm   250 QFIVLSSI------GMYGFEDLQIGNSYEIARRHNCTSE----NSQEIVDCMRNIDALQLLQTQT 304

  Fly   359 WNSYSGILSFPSAPTIDGAFLPADPM--TLMKTADLKD----YDILMGNVRDEGT-------YFL 410
            ......:|.|.       |.:.|.|:  ...|.::.|:    .::|.|...:|.|       |::
 Worm   305 VMDDVDLLFFK-------AIIRAPPLMDVKQKLSEFKENVTARNMLCGVTDNEFTIFKYPDGYYI 362

  Fly   411 LYDFIDYFDKDDATALPRDKYLEIMNNIFGKATQAEREAIIFQYTSWEGNPGYQNQQQIGRAVGD 475
            ...|:|:.:..|...:.|:|:..|                         .|.:.|..  ..||
 Worm   363 SATFLDFENPVDTVNVYRNKFTNI-------------------------TPTFVNSD--SSAV-- 398

  Fly   476 HFFTCPTNEYAQALAERGASVHYYYFTHRTSTSLWGEWMGVLHGDEIEYFFGQPLNNSLQYRPVE 540
             |.:..|  |::||...|.:|  |.|..|....       .:|..:::||.|           :.
 Worm   399 -FVSAAT--YSEALTNAGGNV--YLFESRQKPF-------SMHVTDMQYFIG-----------IH 440

  Fly   541 RE---------LGKRMLSAVIEFAKTGNPAQDGEEWPNFSKEDPVYYIF-----STDDKIE-KLA 590
            ||         |.......::.|.|.|:|:      ||:.|.||....|     .|:..|| |:.
 Worm   441 REKNHTTDMDILDSFYSKLLVNFTKFGSPS------PNWEKYDPSKMNFMAMEIDTEQGIEPKME 499

  Fly   591 RGPLAARCSFW 601
            .|......:||
 Worm   500 NGFHEELVNFW 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ace	NP_476953.1	COesterase	43..601	CDD:395084	140/594 (24%)
cest-7	NP_001257187.1	alpha/beta hydrolases	38..510	CDD:473884	140/594 (24%)